The DOI matches its Crossref record; 209 of the 209 references it cites were found in a registry or an index.
Membrane Transport in the Malaria-Infected Erythrocyte
Open accessAbstract
The malaria parasite is a unicellular eukaryotic organism which, during the course of its complex life cycle, invades the red blood cells of its vertebrate host. As it grows and multiplies within its host blood cell, the parasite modifies the membrane permeability and cytosolic composition of the host cell. The intracellular parasite is enclosed within a so-called parasitophorous vacuolar membrane, tubular extensions of which radiate out into the host cell compartment. Like all eukaryote cells, the parasite has at its surface a plasma membrane, as well as having a variety of internal membrane-bound organelles that perform a range of functions. This review focuses on the transport properties of the different membranes of the malaria-infected erythrocyte, as well as on the role played by the various membrane transport systems in the uptake of solutes from the extracellular medium, the disposal of metabolic wastes, and the origin and maintenance of electrochemical ion gradients. Such systems are of considerable interest from the point of view of antimalarial chemotherapy, both as drug targets in their own right and as routes for targeting cytotoxic agents into the intracellular parasite.
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Items 201–209 of 209
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Characterization of peptide fluxes into human erythrocytes. A proton-n.m.r. study
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Plasmodium falciparum:Transport of Entantiomers of Nucleosides into Sendai-Treated Trophozoites
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Macromolecular Transport in Malaria‐Infected Erythrocytes
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Erythrocyte programmed cell death
Föller, M., Huber, S. M., & Lang, F. (2008) · IUBMB Life · doi:10.1002/iub.106 · Cited by 314
Pentamidine uptake and resistance in pathogenic protozoa: past, present and future
Bray, P. G., Barrett, M. P., Ward, S. A., & de Koning, H. P. (2003) · Trends in Parasitology · doi:10.1016/s1471-4922(03)00069-2 · Cited by 261
Human cerebral malaria and the blood–brain barrier
Medana, I. M., & Turner, G. D. H. (2006) · International Journal for Parasitology · doi:10.1016/j.ijpara.2006.02.004 · Cited by 255
Nutrient acquisition by intracellular apicomplexan parasites: staying in for dinner
Saliba, K. J., & Kirk, K. (2001) · International Journal for Parasitology · doi:10.1016/s0020-7519(01)00258-2 · Cited by 68
Self-citationAdaptation of targeted nanocarriers to changing requirements in antimalarial drug delivery
Marques, J., Valle-Delgado, J. J., Urbán, P., Baró, E., Prohens, R., Mayor, A., Cisteró, P., Delves, M., Sinden, R. E., Grandfils, C., et al. (2017) · Nanomedicine: Nanotechnology, Biology and Medicine · doi:10.1016/j.nano.2016.09.010 · Cited by 64
Metadata
- Authors
- Kirk, K.
- Venue
- Physiological Reviews
- Publisher
- American Physiological Society
- Published
- 2001-04-01
- Volume
- 81
- Issue
- 2
- Pages
- 495-537
- ISSN
- 0031-9333 (ISSN-L)
- 1522-1210
- OpenAlex
- W2136690044
- Cited by
- 405
- References
- 209
- FWCI
- 3.73
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
