Enhancement of Neocortical-Medial Temporal EEG Correlations during Non-REM Sleep
Open accessAbstract
Interregional interactions of oscillatory activity are crucial for the integrated processing of multiple brain regions. However, while the EEG in virtually all brain structures passes through substantial modifications during sleep, it is still an open question whether interactions between neocortical and medial temporal EEG oscillations also depend on the state of alertness. Several previous studies in animals and humans suggest that hippocampal-neocortical interactions crucially depend on the state of alertness (i.e., waking state or sleep). Here, we analyzed scalp and intracranial EEG recordings during sleep and waking state in epilepsy patients undergoing presurgical evaluation. We found that the amplitudes of oscillations within the medial temporal lobe and the neocortex were more closely correlated during sleep, in particular during non-REM sleep, than during waking state. Possibly, the encoding of novel sensory inputs, which mainly occurs during waking state, requires that medial temporal dynamics are rather independent from neocortical dynamics, while the consolidation of memories during sleep may demand closer interactions between MTL and neocortex.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Compared with wakefulness or SWS, EEG activity during REM sleep shows reduced coherence between limbic-hippocampal and neocortical circuitry in a wide range of frequencies including theta and gamma.
“Compared with wakefulness or SWS, EEG activity during REM sleep shows reduced coherence between limbic-hippocampal and neocortical circuitry in a wide range of frequencies including theta and gamma (51,174,293).”
From About Sleep's Role in Memory (2013) · cites this paper as [51]
The Discussion (page unavailable) reports that hippocampal theta activity during REM sleep was independent of neocortical theta activity, and the Results find a REM–NREM difference in delta-band correlations. But the Results find no significant wake–REM difference in delta and only trends for REM–NREM differences in alpha and gamma; they do not establish reduced REM coherence versus wakefulness or SWS across a wide range of frequencies. The paper also measures correlations of EEG power rather than coherence. (LLM, conf=0.88)
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
The citation lists haven’t been fetched yet
References 39 · Cited by 22
Research works printed but not linked: 3
- [10]Klopp J Marinkovic K Chauvel P Nenov V Halgren E Early widespread cortical distribution of coherent fusiform face selective activity Human Brain Mapping 2000 11 4 286 293 11144757 PMC6871879
- [21]Steriade M Neuronal Substrates of Sleep and Epilepsy 2003 Cambridge, UK Cambridge University Press
- [36]Lachaux J-P Rodriguez E Martinerie J Varela FJ Measuring phase synchrony in brain signals Human Brain Mapping 1999 8 4 194 208 10619414 PMC6873296
- Authors
- Axmacher, N., Helmstaedter, C., Elger, C. E., & Fell, J.
- Affiliations
- University of Bonn (DE)
- Corresponding author
- Axmacher, Nikolai
- Venue
- Neural Plasticity
- Publisher
- Wiley
- Published
- 2008
- Volume
- 2008
- Pages
- 1-7
- ISSN
- 1687-5443 (ISSN-L)
- 2090-5904
- PMC
- PMC2430382
- OpenAlex
- W1985952920
- Cited by
- 22
- References
- 39
- Citations by year
- 2022: 2 · 2020: 1 · 2018: 1 · 2016: 3 · 2015: 2 · 2014: 2 · 2013: 2 · 2012: 1
- FWCI
- 1.38
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Neural Plasticity (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Deutsche Forschungsgemeinschaft (DFG El-122-8)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Keywords
- neocortex, medial temporal lobe, EEG oscillations, NREM sleep, hippocampal-neocortical interaction, memory consolidation, epilepsy, preoperative assessment, intracranial EEG
- MeSH terms
- Adult, Electroencephalography, Female, Humans, Male, Sleep, Sleep Stages, Sleep, REM, Polysomnography, Neocortex
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
