The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Acne Scars: Pathogenesis, Classification and Treatment
Open accessAbstract
Acne has a prevalence of over 90% among adolescents and persists into adulthood in approximately 12%–14% of cases with psychological and social implications. Possible outcomes of the inflammatory acne lesions are acne scars which, although they can be treated in a number of ways, may have a negative psychological impact on social life and relationships. The main types of acne scars are atrophic and hypertrophic scars. The pathogenesis of acne scarring is still not fully understood, but several hypotheses have been proposed. There are numerous treatments: chemical peels, dermabrasion/microdermabrasion, laser treatment, punch techniques, dermal grafting, needling and combined therapies for atrophic scars: silicone gels, intralesional steroid therapy, cryotherapy, and surgery for hypertrophic and keloidal lesions. This paper summarizes acne scar pathogenesis, classification and treatment options.
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“Clinically, efficient keratinocyte migration is essential for re-epithelialization and barrier restoration, and impaired migration has been associated with delayed healing and the development of atrophic acne scarring [55].”
From Dissolvable silk microneedles delivering minocycline-loaded ZIF-8 nanoparticles for targeted modulation of sebocyte metabolism and improved acne therapy (2026) · cites this paper as [55]
In the citing paper
“Clinically, efficient keratinocyte migration is essential for re-epithelialization and barrier restoration, and impaired migration has been associated with delayed healing and the development of atrophic acne scarring [55].”
From Dissolvable silk microneedles delivering minocycline-loaded ZIF-8 nanoparticles for targeted modulation of sebocyte metabolism and improved acne therapy (2026) · cites this paper as [55]
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Citations
Cites
Inflammatory cells during wound repair: the good, the bad and the ugly
Martin, P., & Leibovich, S. J. (2005) · Trends in Cell Biology · doi:10.1016/j.tcb.2005.09.002 · Cited by 1,340 · cited 1×
“A variety of blood cells, including granulocytes, macrophages, neutrophils lymphocytes, fibroblasts, and platelets, are activated and release inflammatory mediators, which ready the site for granulation tissue formation [14].”
BackgroundTissue repair and the dynamics of the extracellular matrix
Midwood, K. S., Williams, L. V., & Schwarzbauer, J. E. (2004) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2003.12.003 · Cited by 919
New developments in our understanding of acne pathogenesis and treatment
Kurokawa, I., Danby, F. W., Ju, Q., Wang, X., Xiang, L. F., Xia, L., Chen, W., Nagy, I., Picardo, M., Suh, D. H., et al. (2009) · Experimental Dermatology · doi:10.1111/j.1600-0625.2009.00890.x · Cited by 584
Acne and sebaceous gland function
Zouboulis, C. C. (2004) · Clinics in Dermatology · doi:10.1016/j.clindermatol.2004.03.004 · Cited by 561 · cited 1×
“Neutral and polar lipids produced by sebaceous glands serve a variety of roles in signal transduction and are involved in biological pathways [7].”
BackgroundNagy, I., Pivarcsi, A., Kis, K., Koreck, A., Bodai, L., McDowell, A., Seltmann, H., Patrick, S., Zouboulis, C. C., & Kemény, L. (2006) · Microbes and Infection · doi:10.1016/j.micinf.2006.04.001 · Cited by 375
Alestas, T., Ganceviciene, R., Fimmel, S., Müller-Decker, K., & Zouboulis, C. C. (2006) · Journal of Molecular Medicine · doi:10.1007/s00109-005-0715-8 · Cited by 269
Makrantonaki, E., & Zouboulis, C. C. (2007) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2006.07671.x · Cited by 117
Cited by
Why Topical Retinoids Are Mainstay of Therapy for Acne
Leyden, J., Stein-Gold, L., & Weiss, J. (2017) · Dermatology and Therapy · doi:10.1007/s13555-017-0185-2 · Cited by 164
Heng, A. H. S., Say, Y.-H., Sio, Y. Y., Ng, Y. T., & Chew, F. T. (2022) · Dermatology · doi:10.1159/000516232 · Cited by 48
Dal Belo, S. E., Kanoun‐Copy, L., Lambert, C., Cornillon, C., Muller, B., Jouni, H., Moreau, M., Palamarchuk, I., Kerob, D., & Aguilar, L. (2024) · Journal of Cosmetic Dermatology · doi:10.1111/jocd.16052 · Cited by 17
Yang, X., Ruan, D., Ye, F., Qiu, X., Li, S., Huang, L., Zouboulis, C. C., Mo, X., Jiang, X., & Ju, Q. (2026) · Journal of Nanobiotechnology · doi:10.1186/s12951-026-04221-8 · Cited by 4
Metadata
- Authors
- Fabbrocini, G., Annunziata, M. C., D′Arco, V., De Vita, V., Lodi, G., Mauriello, M. C., Pastore, F., & Monfrecola, G.
- Venue
- Dermatology Research and Practice
- Publisher
- Wiley
- Published
- 2010-01
- Volume
- 2010
- Issue
- 1
- Pages
- 893080-893080
- ISSN
- 1687-6105 (ISSN-L)
- 1687-6113
- OpenAlex
- W2142384367
- Cited by
- 440
- References
- 7
- FWCI
- 9.98
- Type
- journal article
- Language
- en
- Open access
- gold
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- Fabbrocini, G., Annunziata, M. C., D′Arco, V., De Vita, V., Lodi, G., Mauriello, M. C., Pastore, F., & Monfrecola, G. (2010). Acne Scars: Pathogenesis, Classification and Treatment. Dermatology Research and Practice. https://doi.org/10.1155/2010/893080
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
