The DOI matches its Crossref record; 213 of the 213 references it cites were found in a registry or an index.
The Adverse Effects of Air Pollution on the Nervous System
Open accessAbstract
Exposure to ambient air pollution is a serious and common public health concern associated with growing morbidity and mortality worldwide. In the last decades, the adverse effects of air pollution on the pulmonary and cardiovascular systems have been well established in a series of major epidemiological and observational studies. In the recent past, air pollution has also been associated with diseases of the central nervous system (CNS), including stroke, Alzheimer’s disease, Parkinson’s disease, and neurodevelopmental disorders. It has been demonstrated that various components of air pollution, such as nanosized particles, can easily translocate to the CNS where they can activate innate immune responses. Furthermore, systemic inflammation arising from the pulmonary or cardiovascular system can affect CNS health. Despite intense studies on the health effects of ambient air pollution, the underlying molecular mechanisms of susceptibility and disease remain largely elusive. However, emerging evidence suggests that air pollution-induced neuroinflammation, oxidative stress, microglial activation, cerebrovascular dysfunction, and alterations in the blood-brain barrier contribute to CNS pathology. A better understanding of the mediators and mechanisms will enable the development of new strategies to protect individuals at risk and to reduce detrimental effects of air pollution on the nervous system and mental health.
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Cites
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Cited by
Environmental and Health Impacts of Air Pollution: A Review
Manisalidis, I., Stavropoulou, E., Stavropoulos, A., & Bezirtzoglou, E. (2020) · Frontiers in Public Health · doi:10.3389/fpubh.2020.00014 · Cited by 5,269
Lifestyle medicine for depression
Sarris, J., O’Neil, A., Coulson, C. E., Schweitzer, I., & Berk, M. (2014) · BMC Psychiatry · doi:10.1186/1471-244x-14-107 · Cited by 450
Recent Advances in Electrochemical Sensors for Detecting Toxic Gases: NO2, SO2 and H2S
Khan, M. A. H., Rao, M. V., & Li, Q. (2019) · Sensors · doi:10.3390/s19040905 · Cited by 417
Exposure to ambient air pollution and the incidence of dementia: a population-based cohort study
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Is there a link between air pollution and mental disorders?
Buoli, M., Grassi, S., Caldiroli, A., Carnevali, G. S., Mucci, F., Iodice, S., Cantone, L., Pergoli, L., & Bollati, V. (2018) · Environment International · doi:10.1016/j.envint.2018.05.044 · Cited by 370
Metadata
- Authors
- Genc, S., Zadeoglulari, Z., Fuss, S. H., & Genc, K.
- Venue
- Journal of Toxicology
- Publisher
- Hindawi Limited
- Published
- 2012
- Volume
- 2012
- Pages
- 1-23
- ISSN
- 1687-8191 (ISSN-L)
- 1687-8205
- OpenAlex
- W2031605875
- Cited by
- 717
- References
- 213
- FWCI
- 11.80
- Type
- journal article
- Language
- en
- Open access
- gold
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