Alzheimer's disease

Diagnosis and management of dementia with Lewy bodies: Third report of the DLB consortium

McKeith, I. G., Dickson, D. W., Lowe, J., Emre, M., O'Brien, J. T., Feldman, H., Cummings, J., Duda, J. E., Lippa, C., Perry, E. K., et al. (2005) · Neurology · doi:10.1212/01.wnl.0000187889.17253.b1 · Cited by 5,069 · see citing works

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

Harold, D., Abraham, R., Hollingworth, P., Sims, R., Gerrish, A., Hamshere, M. L., Pahwa, J. S., Moskvina, V., Dowzell, K., Williams, A., et al. (2009) · Nature Genetics · doi:10.1038/ng.440 · Cited by 3,326 · see citing works

Immunization with amyloid-β attenuates Alzheimer-disease-like pathology in the PDAPP mouse

Schenk, D., Barbour, R., Dunn, W., Gordon, G., Grajeda, H., Guido, T., Hu, K., Huang, J., Johnson-Wood, K., Khan, K., et al. (1999) · Nature · doi:10.1038/22124 · Cited by 3,160 · see citing works

Candidate gene for the chromosome 1 familial Alzheimer’s disease locus

Levy-Lahad, E., Wasco, W., Poorkaj, P., Romano, D. M., Oshima, J., Pettingell, W. H., Yu, C.-E., Jondro, P. D., Schmidt, S. D., Wang, K., et al. (1995) · Science · doi:10.1126/science.7638622 · Cited by 2,577 · see citing works

Transmission and spreading of tauopathy in transgenic mouse brain

Clavaguera, F., Bolmont, T., Crowther, R. A., Abramowski, D., Frank, S., Probst, A., Fraser, G., Stalder, A. K., Beibel, M., Staufenbiel, M., et al. (2009) · Nature Cell Biology · doi:10.1038/ncb1901 · Cited by 1,803 · see citing works

Long-term effects of Aβ42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial

Holmes, C., Boche, D., Wilkinson, D., Yadegarfar, G., Hopkins, V., Bayer, A., Jones, R. W., Bullock, R., Love, S., Neal, J. W., et al. (2008) · The Lancet · doi:10.1016/s0140-6736(08)61075-2 · Cited by 1,416 · see citing works

CSF Biomarkers and Incipient Alzheimer Disease in Patients With Mild Cognitive Impairment

Mattsson, N. (2009) · JAMA · doi:10.1001/jama.2009.1064 · Cited by 1,176 · see citing works

Putting brain training to the test

Owen, A. M., Hampshire, A., Grahn, J. A., Stenton, R., Dajani, S., Burns, A. S., Howard, R. J., & Ballard, C. G. (2010) · Nature · doi:10.1038/nature09042 · Cited by 1,056 · see citing works

Physical activity and risk of neurodegenerative disease: a systematic review of prospective evidence

Hamer, M., & Chida, Y. (2009) · Psychological Medicine · doi:10.1017/s0033291708003681 · Cited by 988 · see citing works

Metal-Protein Attenuation With Iodochlorhydroxyquin (Clioquinol) Targeting Aβ Amyloid Deposition and Toxicity in Alzheimer Disease: A Pilot Phase 2 Clinical Trial

Ritchie, C. W., Bush, A. I., Mackinnon, A., Macfarlane, S., Mastwyk, M., MacGregor, L., Kiers, L., Cherny, R., Li, Q.-X., Tammer, A., et al. (2003) · Archives of Neurology · doi:10.1001/archneur.60.12.1685 · Cited by 988 · see citing works

Brain reserve and dementia: a systematic review

VALENZUELA, M. J., & SACHDEV, P. (2006) · Psychological Medicine · doi:10.1017/s0033291705006264 · Cited by 932 · see citing works

Fibrillar amyloid-β burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease

Reiman, E. M., Chen, K., Liu, X., Bandy, D., Yu, M., Lee, W., Ayutyanont, N., Keppler, J., Reeder, S. A., Langbaum, J. B. S., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0900345106 · Cited by 785 · see citing works

Effect of Tarenflurbil on Cognitive Decline and Activities of Daily Living in Patients With Mild Alzheimer Disease<subtitle>A Randomized Controlled Trial</subtitle>

Green, R. C. (2009) · JAMA · doi:10.1001/jama.2009.1866 · Cited by 643 · see citing works

Caring for Aged Dementia Care Resident Study (CADRES) of person-centred care, dementia-care mapping, and usual care in dementia: a cluster-randomised trial

Chenoweth, L., King, M. T., Jeon, Y.-H., Brodaty, H., Stein-Parbury, J., Norman, R., Haas, M., & Luscombe, G. (2009) · The Lancet Neurology · doi:10.1016/s1474-4422(09)70045-6 · Cited by 528 · see citing works

Diabetes and the Risk of Multi-System Aging Phenotypes: A Systematic Review and Meta-Analysis

Lu, F.-P., Lin, K.-P., & Kuo, H.-K. (2009) · PLoS ONE · doi:10.1371/journal.pone.0004144 · Cited by 398 · see citing works

Overexpression of Dyrk1A contributes to neurofibrillary degeneration in down syndrome

Liu, F., Liang, Z., Wegiel, J., Hwang, Y., Iqbal, K., Grundke‐Iqbal, I., Ramakrishna, N., & Gong, C. (2008) · The FASEB Journal · doi:10.1096/fj.07-104539 · Cited by 272 · see citing works

Long-term effects of the concomitant use of memantine with cholinesterase inhibition in Alzheimer disease

Lopez, O. L., Becker, J. T., Wahed, A. S., Saxton, J., Sweet, R. A., Wolk, D. A., Klunk, W., & DeKosky, S. T. (2009) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.2008.158964 · Cited by 266 · see citing works

Epidemiological Studies of the Effect of Stroke on Incident Dementia: A Systematic Review

Savva, G. M., Stephan, B. C. M., & the Alzheimer’s Society Vascular Dementia Systematic Review Group (2010) · Stroke · doi:10.1161/strokeaha.109.559880 · Cited by 257 · see citing works

Midlife Dietary Intake of Antioxidants and Risk of Late-Life Incident Dementia: The Honolulu-Asia Aging Study

Laurin, D. (2004) · American Journal of Epidemiology · doi:10.1093/aje/kwh124 · Cited by 231 · see citing works

Statins for the prevention of dementia

McGuinness, B., Craig, D., Bullock, R., & Passmore, P. (2009) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd003160.pub2 · Cited by 193 · see citing works

Combined CSF tau, p-tau181 and amyloid-β 38/40/42 for diagnosing Alzheimer’s disease

Welge, V., Fiege, O., Lewczuk, P., Mollenhauer, B., Esselmann, H., Klafki, H.-W., Wolf, S., Trenkwalder, C., Otto, M., Kornhuber, J., et al. (2009) · Journal of Neural Transmission · doi:10.1007/s00702-008-0177-6 · Cited by 152 · see citing works

Lithium treatment arrests the development of neurofibrillary tangles in mutant tau transgenic mice with advanced neurofibrillary pathology.

Leroy, K., Ando, K., Héraud, C., Yilmaz, Z., Authelet, M., Boeynaems, J.-M., Buée, L., De Decker, R., & Brion, J.-P. (2010) · Journal of Alzheimer's Disease · doi:10.3233/jad-2010-1276 · Cited by 103 · see citing works

Plasma tocopherols and risk of cognitive impairment in an elderly Italian cohort

Ravaglia, G., Forti, P., Lucicesare, A., Pisacane, N., Rietti, E., Mangialasche, F., Cecchetti, R., Patterson, C., & Mecocci, P. (2008) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/87.5.1306 · Cited by 59 · see citing works

Systematic review: blood pressure lowering in patients without prior cerebrovascular disease for prevention of cognitive impairment and dementia

McGuinness, B., Todd, S., Passmore, A. P., & Bullock, R. (2008) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.2007.118505 · Cited by 57 · see citing works

A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease

Keren-Shaul, H., Spinrad, A., Weiner, A., Matcovitch-Natan, O., Dvir-Szternfeld, R., Ulland, T. K., David, E., Baruch, K., Lara-Astaiso, D., Toth, B., et al. (2017) · Cell · doi:10.1016/j.cell.2017.05.018 · Cited by 5,493 · see citing works

The amyloid state and its association with protein misfolding diseases.

Knowles, T. P. J., Vendruscolo, M., & Dobson, C. M. (2014) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3810 · Cited by 2,382 · see citing works

Defeating Alzheimer's disease and other dementias: a priority for European science and society

Winblad, B., Amouyel, P., Andrieu, S., Ballard, C., Brayne, C., Brodaty, H., Cedazo-Minguez, A., Dubois, B., Edvardsson, D., Feldman, H., et al. (2016) · The Lancet Neurology · doi:10.1016/s1474-4422(16)00062-4 · Cited by 1,676 · see citing works

Education and cognitive functioning across the life span

Lövdén, M., Fratiglioni, L., Glymour, M. M., Lindenberger, U., & Tucker-Drob, E. M. (2020) · Psychological Science in the Public Interest · doi:10.1177/1529100620920576 · Cited by 1,224 · see citing works

Timing of onset of cognitive decline: results from Whitehall II prospective cohort study

Singh-Manoux, A., Kivimaki, M., Glymour, M. M., Elbaz, A., Berr, C., Ebmeier, K. P., Ferrie, J. E., & Dugravot, A. (2012) · BMJ · doi:10.1136/bmj.d7622 · Cited by 836 · see citing works

Probing and regulating dysfunctional circuits using deep brain stimulation

Lozano, A. M., & Lipsman, N. (2013) · Neuron · doi:10.1016/j.neuron.2013.01.020 · Cited by 665 · see citing works

The Alzheimer’s Disease Clinical Spectrum

Atri, A. (2019) · Medical Clinics of North America · doi:10.1016/j.mcna.2018.10.009 · Cited by 623 · see citing works

The probabilistic model of Alzheimer disease: the amyloid hypothesis revised

Frisoni, G. B., Altomare, D., Thal, D. R., Ribaldi, F., van der Kant, R., Ossenkoppele, R., Blennow, K., Cummings, J., van Duijn, C., Nilsson, P. M., et al. (2022) · Nature Reviews Neuroscience · doi:10.1038/s41583-021-00533-w · Cited by 513 · see citing works

Role of gut-brain axis, gut microbial composition, and probiotic intervention in Alzheimer's disease

Kesika, P., Suganthy, N., Sivamaruthi, B. S., & Chaiyasut, C. (2021) · Life Sciences · doi:10.1016/j.lfs.2020.118627 · Cited by 479 · see citing works

Benzodiazepine use and risk of dementia: prospective population based study

Billioti de Gage, S., Begaud, B., Bazin, F., Verdoux, H., Dartigues, J.-F., Peres, K., Kurth, T., & Pariente, A. (2012) · BMJ · doi:10.1136/bmj.e6231 · Cited by 436 · see citing works

Astrocytes in Neurodegenerative Disease: Table 1.

Phatnani, H., & Maniatis, T. (2015) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a020628 · Cited by 420 · see citing works

Modifiable pathways in Alzheimer’s disease: Mendelian randomisation analysis

Larsson, S. C., Traylor, M., Malik, R., Dichgans, M., Burgess, S., & Markus, H. S. (2017) · BMJ · doi:10.1136/bmj.j5375 · Cited by 382 · see citing works

Regulation of blood-brain barrier integrity by microglia in health and disease: A therapeutic opportunity

Ronaldson, P. T., & Davis, T. P. (2020) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x20951995 · Cited by 392 · see citing works

Tau Aggregation and Its Interplay with Amyloid-β

Nisbet, R. M., Polanco, J.-C., Ittner, L. M., & Götz, J. (2015) · Acta Neuropathologica · doi:10.1007/s00401-014-1371-2 · Cited by 359 · see citing works

Microglia in the Neuroinflammatory Pathogenesis of Alzheimer’s Disease and Related Therapeutic Targets

Cai, Y., Liu, J., Wang, B., Sun, M., & Yang, H. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.856376 · Cited by 351 · see citing works

Genetics of dementia

Loy, C. T., Schofield, P. R., Turner, A. M., & Kwok, J. B. (2014) · The Lancet · doi:10.1016/s0140-6736(13)60630-3 · Cited by 342 · see citing works

Dual-drug loaded nanoparticles of Epigallocatechin-3-gallate (EGCG)/Ascorbic acid enhance therapeutic efficacy of EGCG in a APPswe/PS1dE9 Alzheimer's disease mice model

Cano, A., Ettcheto, M., Chang, J.-H., Barroso, E., Espina, M., Kühne, B. A., Barenys, M., Auladell, C., Folch, J., Souto, E. B., et al. (2019) · Journal of Controlled Release · doi:10.1016/j.jconrel.2019.03.010 · Cited by 337 · see citing works

Wnt signaling in the nervous system and in Alzheimer's disease

Inestrosa, N. C., & Varela-Nallar, L. (2014) · Journal of Molecular Cell Biology · doi:10.1093/jmcb/mjt051 · Cited by 324 · see citing works

Alzheimer’s disease: analyzing the missing heritability

Ridge, P. G., Mukherjee, S., Crane, P. K., Kauwe, J. S. K., & Alzheimer’s Disease Genetics Consortium (2013) · PLoS ONE · doi:10.1371/journal.pone.0079771 · Cited by 328 · see citing works

Chronic stress and glucocorticoids: From neuronal plasticity to neurodegeneration

Vyas, S., Rodrigues, A. J., Silva, J. M., Tronche, F., Almeida, O. F. X., Sousa, N., & Sotiropoulos, I. (2016) · Neural Plasticity · doi:10.1155/2016/6391686 · Cited by 297 · see citing works

The dual roles of cytokines in Alzheimer’s disease: update on interleukins, TNF-α, TGF-β and IFN-γ

Zheng, C., Zhou, X.-W., & Wang, J.-Z. (2016) · Translational Neurodegeneration · doi:10.1186/s40035-016-0054-4 · Cited by 292 · see citing works

Molecular Pathogenesis of the Tauopathies

Götz, J., Halliday, G., & Nisbet, R. M. (2019) · Annual Review of Pathology: Mechanisms of Disease · doi:10.1146/annurev-pathmechdis-012418-012936 · Cited by 276 · see citing works

Comorbidity of dementia: a cross-sectional study of primary care older patients

Poblador-Plou, B., Calderón-Larrañaga, A., Marta-Moreno, J., Hancco-Saavedra, J., Sicras-Mainar, A., Soljak, M., & Prados-Torres, A. (2014) · BMC Psychiatry · doi:10.1186/1471-244x-14-84 · Cited by 256 · see citing works

Neuroinflammation and neurodegeneration in overnutrition-induced diseases

Cai, D. (2013) · Trends in Endocrinology & Metabolism · doi:10.1016/j.tem.2012.11.003 · Cited by 256 · see citing works

Alzheimer’s disease and gut microbiota modifications: The long way between preclinical studies and clinical evidence

Mancuso, C., & Santangelo, R. (2018) · Pharmacological Research · doi:10.1016/j.phrs.2017.12.009 · Cited by 232 · see citing works

Genetically engineered pigs as models for human disease

Perleberg, C., Kind, A., & Schnieke, A. (2018) · Disease Models & Mechanisms · doi:10.1242/dmm.030783 · Cited by 222 · see citing works

Friends or foes: matrix metalloproteinases and their multifaceted roles in neurodegenerative diseases

Brkic, M., Balusu, S., Libert, C., & Vandenbroucke, R. E. (2015) · Mediators of Inflammation · doi:10.1155/2015/620581 · Cited by 205 · see citing works

Viral vectors for therapy of neurologic diseases

Choudhury, S. R., Hudry, E., Maguire, C. A., Sena-Esteves, M., Breakefield, X. O., & Grandi, P. (2017) · Neuropharmacology · doi:10.1016/j.neuropharm.2016.02.013 · Cited by 190 · see citing works

MicroRNAs and neurodegeneration: role and impact

Abe, M., & Bonini, N. M. (2013) · Trends in Cell Biology · doi:10.1016/j.tcb.2012.08.013 · Cited by 190 · see citing works

Insulin-Degrading Enzyme in the Fight against Alzheimer's Disease

Kurochkin, I. V., Guarnera, E., & Berezovsky, I. N. (2018) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2017.10.008 · Cited by 185 · see citing works

Hypothalamic Alterations in Neurodegenerative Diseases and Their Relation to Abnormal Energy Metabolism

Vercruysse, P., Vieau, D., Blum, D., Petersén, Å., & Dupuis, L. (2018) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2018.00002 · Cited by 172 · see citing works

Defining Alzheimer as a common age-related neurodegenerative process not inevitably leading to dementia

Ferrer, I. (2012) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2012.03.005 · Cited by 174 · see citing works

Resveratrol Brain Delivery for Neurological Disorders Prevention and Treatment

Andrade, S., Ramalho, M. J., Pereira, M. D. C., & Loureiro, J. A. (2018) · Frontiers in Pharmacology · doi:10.3389/fphar.2018.01261 · Cited by 173 · see citing works

Neurocognitive Effect of Nootropic Drug <b><i>Brahmi</i></b> (<b><i>Bacopa monnieri</i></b>) in Alzheimer's Disease

Chaudhari, K. S., Tiwari, N. R., Tiwari, R. R., & Sharma, R. S. (2017) · Annals of Neurosciences · doi:10.1159/000475900 · Cited by 167 · see citing works

The P2X7 Receptor: Central Hub of Brain Diseases

Andrejew, R., Oliveira-Giacomelli, Á., Ribeiro, D. E., Glaser, T., Arnaud-Sampaio, V. F., Lameu, C., & Ulrich, H. (2020) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2020.00124 · Cited by 162 · see citing works

Protective Effect of Amyloid-β Peptides Against Herpes Simplex Virus-1 Infection in a Neuronal Cell Culture Model

Bourgade, K., Le Page, A., Bocti, C., Witkowski, J. M., Dupuis, G., Frost, E. H., & Fülöp, T. (2016) · Journal of Alzheimer’s Disease · doi:10.3233/jad-150652 · Cited by 161 · see citing works

Predicting probable Alzheimer's disease using linguistic deficits and biomarkers

Orimaye, S. O., Wong, J. S.-M., Golden, K. J., Wong, C. P., & Soyiri, I. N. (2017) · BMC Bioinformatics · doi:10.1186/s12859-016-1456-0 · Cited by 158 · see citing works

A medicinal chemistry perspective of drug repositioning: Recent advances and challenges in drug discovery

Pillaiyar, T., Meenakshisundaram, S., Manickam, M., & Sankaranarayanan, M. (2020) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2020.112275 · Cited by 140 · see citing works

Hearing, cognition, and healthy aging: Social and public health implications of the links between age-related declines in hearing and cognition.

Mick, P., Reed, M., & Pichora-Fuller, M. (2015) · Seminars in Hearing · doi:10.1055/s-0035-1555116 · Cited by 138 · see citing works

GWAS of longitudinal amyloid accumulation on¹⁸F-florbetapir PET in Alzheimer’s disease implicates microglial activation gene<i>IL1RAP</i>

Ramanan, V. K., Risacher, S. L., Nho, K., Kim, S., Shen, L., McDonald, B. C., Yoder, K. K., Hutchins, G. D., West, J. D., Tallman, E. F., et al. (2015) · Brain · doi:10.1093/brain/awv231 · Cited by 133 · see citing works

Reelin delays amyloid-beta fibril formation and rescues cognitive deficits in a model of Alzheimer’s disease

Pujadas, L., Rossi, D., Andrés, R., Teixeira, C. M., Serra-Vidal, B., Parcerisas, A., Maldonado, R., Giralt, E., Carulla, N., & Soriano, E. (2014) · Nature Communications · doi:10.1038/ncomms4443 · Cited by 129 · see citing works

When Does Alzheimer′s Disease Really Start? The Role of Biomarkers

Lloret, A., Esteve, D., Lloret, M.-A., Cervera-Ferri, A., Lopez, B., Nepomuceno, M., & Monllor, P. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20225536 · Cited by 131 · see citing works

The Future of Precision Medicine in the Cure of Alzheimer’s Disease

Arafah, A., Khatoon, S., Rasool, I., Khan, A., Rather, M. A., Abujabal, K. A., Faqih, Y. A. H., Rashid, H., Rashid, S. M., Bilal Ahmad, S., et al. (2023) · Biomedicines · doi:10.3390/biomedicines11020335 · Cited by 133 · see citing works

Patterns of cognitive decline prior to dementia in persons with mild cognitive impairment

Cloutier, S., Chertkow, H., Kergoat, M.-J., Gauthier, S., & Belleville, S. (2015) · Journal of Alzheimer's Disease · doi:10.3233/jad-142910 · Cited by 124 · see citing works

Connecting the dots between tau dysfunction and neurodegeneration

Frost, B., Götz, J., & Feany, M. B. (2015) · Trends in Cell Biology · doi:10.1016/j.tcb.2014.07.005 · Cited by 124 · see citing works

Increased plasma beta-secretase 1 may predict conversion to Alzheimer’s disease dementia in individuals with mild cognitive impairment

Shen, Y., Wang, H., Sun, Q., Yao, H., Keegan, A. P., Mullan, M., Wilson, J., Lista, S., Leyhe, T., Laske, C., et al. (2018) · Biological Psychiatry · doi:10.1016/j.biopsych.2017.02.007 · Cited by 123 · see citing works

Traumatic brain injury and risk of dementia and Alzheimer's disease: a systematic review and meta-analysis

Gu, D., Ou, S., & Liu, G. (2022) · Neuroepidemiology · doi:10.1159/000520966 · Cited by 94 · see citing works

Biogenic metallic elements in the human brain?

Everett, J., Lermyte, F., Brooks, J., Tjendana-Tjhin, V., Plascencia-Villa, G., Hands-Portman, I., Donnelly, J. M., Billimoria, K., Perry, G., Zhu, X., et al. (2021) · Science Advances · doi:10.1126/sciadv.abf6707 · Cited by 94 · see citing works

A review of β-amyloid neuroimaging in Alzheimer's disease

Adlard, P. A., Tran, B. A., Finkelstein, D. I., Desmond, P. M., Johnston, L. A., Bush, A. I., & Egan, G. F. (2014) · Frontiers in Neuroscience · doi:10.3389/fnins.2014.00327 · Cited by 93 · see citing works

The relationship between amyloid-beta and brain capillary endothelial cells in Alzheimer’s disease

Su, Q., Guo, J.-H., Zhang, Y.-L., Wang, J., & Zhang, Z.-N. (2022) · Neural Regeneration Research · doi:10.4103/1673-5374.335829 · Cited by 91 · see citing works

Brain-related proteins as potential CSF biomarkers of Alzheimer's disease: A targeted mass spectrometry approach

Begcevic, I., Brinc, D., Brown, M., Martinez-Morillo, E., Goldhardt, O., Grimmer, T., Magdolen, V., Batruch, I., & Diamandis, E. P. (2018) · Journal of Proteomics · doi:10.1016/j.jprot.2018.04.027 · Cited by 81 · see citing works

The association of angiotensin-converting enzyme with biomarkers for Alzheimer’s disease

Jochemsen, H. M., Teunissen, C. E., Ashby, E. L., van der Flier, W. M., Jones, R. E., Geerlings, M. I., Scheltens, P., Kehoe, P. G., & Muller, M. (2014) · Alzheimer's Research &amp; Therapy · doi:10.1186/alzrt257 · Cited by 77 · see citing works

BACE1 molecular docking and anti-Alzheimer’s disease activities of ginsenosides

Choi, R. J., Roy, A., Jung, H. J., Ali, M. Y., Min, B.-S., Park, C. H., Yokozawa, T., Fan, T.-P., Choi, J. S., & Jung, H. A. (2016) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2016.06.013 · Cited by 77 · see citing works

Shared genetic contribution to ischemic stroke and Alzheimer's disease

Traylor, M., Adib‐Samii, P., Harold, D., the Alzheimer's Disease Neuroimaging Initiative, T. I. S. G. C. (., Dichgans, M., Williams, J., Lewis, C. M., Markus, H. S., & and the METASTROKE and International Genomics of Alzheimer's Project (IGAP) investigators (2016) · Annals of Neurology · doi:10.1002/ana.24621 · Cited by 71 · see citing works

Benchmarking machine learning models for late-onset alzheimer’s disease prediction from genomic data

De Velasco Oriol, J., Vallejo, E. E., Estrada, K., Taméz Peña, J. G., & Disease Neuroimaging Initiative, T. A. (2019) · BMC Bioinformatics · doi:10.1186/s12859-019-3158-x · Cited by 71 · see citing works

Aducanumab—Hope or Disappointment for Alzheimer’s Disease

Wojtunik-Kulesza, K., Rudkowska, M., & Orzeł-Sajdłowska, A. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24054367 · Cited by 73 · see citing works

Attitudes of the German general population toward early diagnosis of dementia--results of a representative telephone survey

Luck, T., Luppa, M., Sieber, J., Schomerus, G., Werner, P., König, H.-H., & Riedel-Heller, S. G. (2012) · PLoS ONE · doi:10.1371/journal.pone.0050792 · Cited by 67 · see citing works

Clinical and research diagnostic criteria for Alzheimer's disease

Sarazin, M., de Souza, L. C., Lehéricy, S., & Dubois, B. (2012) · Neuroimaging Clinics of North America · doi:10.1016/j.nic.2011.11.004 · Cited by 64 · see citing works

Structure–Activity Relationships and Computational Investigations into the Development of Potent and Balanced Dual-Acting Butyrylcholinesterase Inhibitors and Human Cannabinoid Receptor 2 Ligands with Pro-Cognitive in Vivo Profiles

Dolles, D., Hoffmann, M., Gunesch, S., Marinelli, O., Möller, J., Santoni, G., Chatonnet, A., Lohse, M. J., Wittmann, H.-J., Strasser, A., et al. (2018) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.7b01760 · Cited by 67 · see citing works

Impact of Alzheimer’s Disease on Caregivers in the United States

Vu, M., Mangal, R., Stead, T., Carlos Lopez-Ortiz, C., & Ganti, L. (2022) · Health Psychology Research · doi:10.52965/001c.37454 · Cited by 62 · see citing works

Loss of the m6A methyltransferase METTL3 in monocyte-derived macrophages ameliorates Alzheimer’s disease pathology in mice

Yin, H., Ju, Z., Zheng, M., Zhang, X., Zuo, W., Wang, Y., Ding, X., Zhang, X., Peng, Y., Li, J., et al. (2023) · PLOS Biology · doi:10.1371/journal.pbio.3002017 · Cited by 62 · see citing works

Dendritic Spine Initiation in Brain Development, Learning and Diseases and Impact of BAR-Domain Proteins

Khanal, P., & Hotulainen, P. (2021) · Cells · doi:10.3390/cells10092392 · Cited by 60 · see citing works

Relationship Between Markers of Insulin Resistance, Markers of Adiposity, HbA1c, and Cognitive Functions in a Middle-Aged Population–Based Sample: the MONA LISA Study

Sanz, C. M., Ruidavets, J.-B., Bongard, V., Marquié, J.-C., Hanaire, H., Ferrières, J., & Andrieu, S. (2013) · Diabetes Care · doi:10.2337/dc12-1017 · Cited by 60 · see citing works

Central and peripheral circadian clocks and their role in Alzheimer's disease

Chauhan, R., Chen, K.-F., Kent, B. A., & Crowther, D. C. (2017) · Disease Models &amp; Mechanisms · doi:10.1242/dmm.030627 · Cited by 58 · see citing works

A Conversational Robot for Older Adults with Alzheimer's Disease

Pou-Prom, C., Raimondo, S., & Rudzicz, F. (2020) · ACM Transactions on Human-Robot Interaction · doi:10.1145/3380785 · Cited by 59 · see citing works

Mass spectrometry: A platform for biomarker discovery and validation for Alzheimer's and Parkinson's diseases

Cilento, E. M., Jin, L., Stewart, T., Shi, M., Sheng, L., & Zhang, J. (2019) · Journal of Neurochemistry · doi:10.1111/jnc.14635 · Cited by 60 · see citing works

Geniposide Ameliorates Cognitive Deficits by Attenuating the Cholinergic Defect and Amyloidosis in Middle-Aged Alzheimer Model Mice

Zhao, C., Zhang, H., Li, H., Lv, C., Liu, X., Li, Z., Xin, W., Wang, Y., & Zhang, W. (2017) · Neuropharmacology · doi:10.1016/j.neuropharm.2016.12.002 · Cited by 59 · see citing works

Licochalcone B, a chalcone derivative from Glycyrrhiza inflata, as a multifunctional agent for the treatment of Alzheimer’s disease

Cao, Y., Xu, W., Huang, Y., & Zeng, X. (2020) · Natural Product Research · doi:10.1080/14786419.2018.1496429 · Cited by 58 · see citing works

Signal Transduction Pathways of Acupuncture for Treating Some Nervous System Diseases.

Lai, H.-C., Chang, Q.-Y., & Hsieh, C.-L. (2019) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2019/2909632 · Cited by 55 · see citing works

Membrane raft domains and remodeling in aging brain

Colin, J., Gregory-Pauron, L., Lanhers, M.-C., Claudepierre, T., Corbier, C., Yen, F. T., Malaplate-Armand, C., & Oster, T. (2016) · Biochimie · doi:10.1016/j.biochi.2016.08.014 · Cited by 55 · see citing works

Neuronal pentraxin receptor-1 is a new cerebrospinal fluid biomarker of Alzheimer’s disease progression

Begcevic, I., Tsolaki, M., Brinc, D., Brown, M., Martinez-Morillo, E., Lazarou, I., Kozori, M., Tagaraki, F., Nenopoulou, S., Gkioka, M., et al. (2018) · F1000Research · doi:10.12688/f1000research.15095.1 · Cited by 51 · see citing works

The E3 ubiquitin ligase Idol controls brain LDL receptor expression, ApoE clearance, and Aβ amyloidosis

Choi, J., Gao, J., Kim, J., Hong, C., Kim, J., & Tontonoz, P. (2015) · Science Translational Medicine · doi:10.1126/scitranslmed.aad1904 · Cited by 49 · see citing works

Insights on the Use of Transgenic Mice Models in Alzheimer’s Disease Research

Pádua, M. S., Guil-Guerrero, J. L., Prates, J. A. M., & Lopes, P. A. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25052805 · Cited by 46 · see citing works

MicroRNAs in Extracellular Vesicles of Alzheimer’s Disease

Li, W., & Zheng, Y. (2023) · Cells · doi:10.3390/cells12101378 · Cited by 43 · see citing works

Pharmacological Agents Targeting γ-Secretase Increase Risk of Cancer and Cognitive Decline in Alzheimer’s Disease Patients: A Systematic Review and Meta-Analysis

Penninkilampi, R., Brothers, H. M., & Eslick, G. D. (2016) · Journal of Alzheimer’s Disease · doi:10.3233/jad-160275 · Cited by 42 · see citing works

Auditory Memory Decay as Reflected by a New Mismatch Negativity Score Is Associated with Episodic Memory in Older Adults at Risk of Dementia

Laptinskaya, D., Thurm, F., Küster, O. C., Fissler, P., Schlee, W., Kolassa, S., von Arnim, C. A. F., & Kolassa, I.-T. (2018) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2018.00005 · Cited by 31 · see citing works

The Effects of Two Polymorphisms on p21cip1 Function and Their Association with Alzheimer’s Disease in a Population of European Descent

Yates, S. C., Zafar, A., Rabai, E. M., Foxall, J. B., Nagy, S., Morrison, K. E., Clarke, C., Esiri, M. M., Christie, S., Smith, A. D., et al. (2015) · PLOS ONE · doi:10.1371/journal.pone.0114050 · Cited by 31 · see citing works

Tacrine‐6‐Ferulic Acid, a Novel Multifunctional Dimer Against <scp>A</scp>lzheimer's Disease, Prevents Oxidative Stress‐Induced Neuronal Death Through Activating <scp>N</scp>rf2/<scp>ARE</scp>/<scp>HO</scp>‐1 Pathway in <scp>HT</scp>22 Cells

Huang, W., Chao, X., Ouyang, Y., Liu, A., He, X., Chen, M., Wang, L., Liu, J., Yu, S., Rapposelli, S., et al. (2012) · CNS Neuroscience &amp; Therapeutics · doi:10.1111/cns.12010 · Cited by 29 · see citing works

Alzheimer’s Disease and Herbal Combination Therapy: A Comprehensive Review

Pradeep, S., Jain, A. S., Dharmashekara, C., Prasad, S. K., Kollur, S. P., Syed, A., & Shivamallu, C. (2020) · Journal of Alzheimer s Disease Reports · doi:10.3233/adr-200228 · Cited by 30 · see citing works

Current therapeutics for Alzheimer’s disease and clinical trials

Xiao, D., & Zhang, C. (2024) · Exploration of Neuroscience · doi:10.37349/en.2024.00048 · Cited by 30 · see citing works

Osteoblast-Derived Lipocalin-2 Regulated by miRNA-96-5p/Foxo1 Advances the Progression of Alzheimer’s Disease

Wu, B.-W., Guo, J.-D., Wu, M.-S., Liu, Y., Lu, M., Zhou, Y.-H., & Han, H.-W. (2020) · Epigenomics · doi:10.2217/epi-2019-0215 · Cited by 20 · see citing works

Fatty acid-based lipidomics and membrane remodeling induced by apoE3 and apoE4 in human neuroblastoma cells

Prasinou, P., Dafnis, I., Giacometti, G., Ferreri, C., Chroni, A., & Chatgilialoglu, C. (2017) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2017.07.001 · Cited by 15 · see citing works

Synaptic Organizers in Alzheimer’s Disease: A Classification Based on Amyloid-β Sensitivity

Lee, A. K., Khaled, H., Chofflet, N., & Takahashi, H. (2020) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2020.00281 · Cited by 14 · see citing works

In-vitro stability and metabolism of a tacrine–silibinin codrug

Zenger, K., Chen, X., Decker, M., & Kraus, B. (2013) · Journal of Pharmacy and Pharmacology · doi:10.1111/jphp.12070 · Cited by 13 · see citing works

Detecting potential causal relationship between multiple risk factors and Alzheimer’s disease using multivariable Mendelian randomization

Zhang, Q., Xu, F., Wang, L., Zhang, W.-D., Sun, C.-Q., & Deng, H.-W. (2020) · Aging · doi:10.18632/aging.103983 · Cited by 13 · see citing works

Joint image synthesis and fusion with converted features for Alzheimer’s disease diagnosis

Chen, Z., Wang, M., Nan, F., Yang, Y., Li, S., Zhou, M., Qi, J., Wang, H., & Yang, P. (2025) · Engineering Applications of Artificial Intelligence · doi:10.1016/j.engappai.2025.111102 · Cited by 9 · see citing works