The DOI matches its Crossref record; 199 of the 199 references it cites were found in a registry or an index.
Herbal Therapies for Type 2 Diabetes Mellitus: Chemistry, Biology, and Potential Application of Selected Plants and Compounds
Open accessAbstract
Diabetes mellitus has been recognized since antiquity. It currently affects as many as 285 million people worldwide and results in heavy personal and national economic burdens. Considerable progress has been made in orthodox antidiabetic drugs. However, new remedies are still in great demand because of the limited efficacy and undesirable side effects of current orthodox drugs. Nature is an extraordinary source of antidiabetic medicines. To date, more than 1200 flowering plants have been claimed to have antidiabetic properties. Among them, one-third have been scientifically studied and documented in around 460 publications. In this review, we select and discuss blood glucose-lowering medicinal herbs that have the ability to modulate one or more of the pathways that regulate insulin resistance,β-cell function, GLP-1 homeostasis, and glucose (re)absorption. Emphasis is placed on phytochemistry, anti-diabetic bioactivities, and likely mechanism(s). Recent progress in the understanding of the biological actions, mechanisms, and therapeutic potential of compounds and extracts of plant origin in type 2 diabetes is summarized. This review provides a source of up-to-date information for further basic and clinical research into herbal therapy for type 2 diabetes. Emerging views on therapeutic strategies for type 2 diabetes are also discussed.
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1 retracted
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Mammalian Sirtuins: Biological Insights and Disease Relevance
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Cited by
Natural Products for the Treatment of Type 2 Diabetes Mellitus
Ríos, J., Francini, F., & Schinella, G. (2015) · Planta Medica · doi:10.1055/s-0035-1546131 · Cited by 446
Endophytic bacteria: a new source of bioactive compounds
Singh, M., Kumar, A., Singh, R., & Pandey, K. D. (2017) · 3 Biotech · doi:10.1007/s13205-017-0942-z · Cited by 365
Unuofin, J. O., & Lebelo, S. L. (2020) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2020/1356893 · Cited by 308
Metadata
- Authors
- Chang, C. L. T., Lin, Y., Bartolome, A. P., Chen, Y.-C., Chiu, S.-C., & Yang, W.-C.
- Venue
- Evidence-Based Complementary and Alternative Medicine
- Publisher
- Wiley
- Published
- 2013
- Volume
- 2013
- Pages
- 1-33
- ISSN
- 1741-427X (ISSN-L)
- 1741-4288
- OpenAlex
- W2029102611
- Cited by
- 274
- References
- 199
- FWCI
- 14.15
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Chang, C. L. T., Lin, Y., Bartolome, A. P., Chen, Y.-C., Chiu, S.-C., & Yang, W.-C. (2013). Herbal Therapies for Type 2 Diabetes Mellitus: Chemistry, Biology, and Potential Application of Selected Plants and Compounds. Evidence-Based Complementary and Alternative Medicine. https://doi.org/10.1155/2013/378657
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
