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Review on Natural Coumarin Lead Compounds for Their Pharmacological Activity
Open accessAbstract
Coumarin (2 H-1-benzopyran-2-one) is a plant-derived natural product known for its pharmacological properties such as anti-inflammatory, anticoagulant, antibacterial, antifungal, antiviral, anticancer, antihypertensive, antitubercular, anticonvulsant, antiadipogenic, antihyperglycemic, antioxidant, and neuroprotective properties. Dietary exposure to benzopyrones is significant as these compounds are found in vegetables, fruits, seeds, nuts, coffee, tea, and wine. In view of the established low toxicity, relative cheapness, presence in the diet, and occurrence in various herbal remedies of coumarins, it appears prudent to evaluate their properties and applications further.
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Cited by
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Thakur, A., Singla, R., & Jaitak, V. (2015) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2015.07.010 · Cited by 489
Rudrapal, M., Rakshit, G., Singh, R. P., Garse, S., Khan, J., & Chakraborty, S. (2024) · Antioxidants · doi:10.3390/antiox13040429 · Cited by 259
Haggie, P. M., Cil, O., Lee, S., Tan, J.-A., Rivera, A. A., Phuan, P.-W., & Verkman, A. S. (2018) · JCI Insight · doi:10.1172/jci.insight.121370 · Cited by 56
Metadata
- Authors
- Venugopala, K. N., Rashmi, V., & Odhav, B.
- Venue
- BioMed Research International
- Publisher
- Wiley
- Published
- 2013
- Volume
- 2013
- Pages
- 1-14
- ISSN
- 1110-7243 (ISSN-L)
- 2314-6133
- 2314-6141
- OpenAlex
- W2011680286
- Cited by
- 959
- References
- 0
- FWCI
- 41.14
- Type
- journal article
- Language
- en
- Open access
- hybrid
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