The DOI matches its Crossref record; 199 of the 199 references it cites were found in a registry or an index.
IL-10: A Multifunctional Cytokine in Viral Infections
Open accessAbstract
The anti-inflammatory master regulator IL-10 is critical to protect the host from tissue damage during acute phases of immune responses. This regulatory mechanism, central to T cell homeostasis, can be hijacked by viruses to evade immunity. IL-10 can be produced by virtually all immune cells, and it can also modulate the function of these cells. Understanding the effects of this multifunctional cytokine is therefore a complex task. In the present review we discuss the factors driving IL-10 production and the cellular sources of the cytokine during antiviral immune responses. We particularly focus on the IL-10 regulatory mechanisms that impact antiviral immune responses and how viruses can use this central regulatory pathway to evade immunity and establish chronic/latent infections.
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Cites
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BackgroundRestoring function in exhausted CD8 T cells during chronic viral infection
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Cited by
Cytokine Storm in COVID-19: The Current Evidence and Treatment Strategies
Tang, Y., Liu, J., Zhang, D., Xu, Z., Ji, J., & Wen, C. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.01708 · Cited by 1,094
Carlini, V., Noonan, D. M., Abdalalem, E., Goletti, D., Sansone, C., Calabrone, L., & Albini, A. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1161067 · Cited by 543
CNS Infection and Immune Privilege
Forrester, J. V., McMenamin, P. G., & Dando, S. J. (2018) · Nature Reviews Neuroscience · doi:10.1038/s41583-018-0070-8 · Cited by 313
Bermejo-Martin, J. F., González-Rivera, M., Almansa, R., Micheloud, D., Tedim, A. P., Domínguez-Gil, M., Resino, S., Martín-Fernández, M., Ryan Murua, P., Pérez-García, F., et al. (2020) · Critical Care · doi:10.1186/s13054-020-03398-0 · Cited by 264
Immunogenicity of bacteriophages
Champagne-Jorgensen, K., Luong, T., Darby, T., & Roach, D. R. (2023) · Trends in Microbiology · doi:10.1016/j.tim.2023.04.008 · Cited by 115
Metadata
- Authors
- Rojas, J. M., Avia, M., Martín, V., & Sevilla, N.
- Venue
- Journal of Immunology Research
- Publisher
- Wiley
- Published
- 2017
- Volume
- 2017
- Pages
- 1-14
- ISSN
- 2314-7156 (ISSN-L)
- 2314-8861
- OpenAlex
- W2589232255
- Cited by
- 408
- References
- 199
- FWCI
- 13.03
- Type
- journal article
- Language
- en
- Open access
- gold
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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