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Cited by 19Organ Donation and TransplantationEthics in Clinical ResearchPalliative Care and End-of-Life Issues

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Organ Donation and Elective Ventilation: A Necessary Strategy

Open access
Escudero, Dolores, Otero, Jesus, Menéndez de León, Begoña, Perez-Basterrechea, Marcos·2017·BioMed Research International

Abstract

Organ transplantation is the sole treatment to improve or save the life of patients with final-stage organ failure. The shortage of available organs for transplantation constitutes a universal problem, estimating that 10% of patients on waiting lists die. Brain death is an undesirable result; nevertheless, it has beneficial side-effects since it is the most frequent source of organs for transplantation. However, this phenomenon is relatively uncommon and has a limited potential. One of the options that focuses on increasing organ donation is to admit patients with catastrophic brain injuries (with a high probability of brain death and nontreatable) to the Intensive Care Unit, with the only purpose of donation. To perform elective nontherapeutic ventilation (ENTV), a patient’s anticipated willingness to donate organs and/or explicit acceptance by his/her relatives is required. This process should focus exclusively on those patients with catastrophic brain injuries and imminent risk of death which, due to its acute damage, are not considered treatable. This article defends ENTV as an effective strategy to improve donation rate, analyzing its ethical and legal basis.

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Figure 1 Clinical decision making. ENTV (elective nontherapeutic ventilation), RAW (registry of anticipated willingness), WLST (withdrawal of life-sustaining treatments), BD (brain death), and ICU (Intensive Care Unit).
Figure 1 Clinical decision making. ENTV (elective nontherapeutic ventilation), RAW (registry of anticipated willingness), WLST (withdrawal of life-sustaining treatments), BD (brain death), and ICU (Intensive Care Unit).CC BY · PubMed Central

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Metadata

Authors
Escudero, D., Otero, J., Menéndez de León, B., & Perez-Basterrechea, M.
Affiliations
  • Hospital Universitario Central de Asturias (ES)
  • Unit of Transplants, Cell Therapy and Regenerative Medicine, Central University Hospital of Asturias, Oviedo, Spain
  • Intensive Care Unit, Central University Hospital of Asturias, Oviedo, Spain
Corresponding author
Escudero, Dolores
Venue
BioMed Research International
Publisher
Wiley
Published
2017
Volume
2017
Pages
1-6
ISSN
  • 1110-7243 (ISSN-L)
  • 2314-6133
  • 2314-6141
OpenAlex
W2577282651
Cited by
19
References
0
Citations by year
2024: 1 · 2023: 2 · 2022: 2 · 2021: 4 · 2020: 1 · 2019: 6 · 2018: 2 · 2017: 1
FWCI
2.57
Type
journal article
Language
en
Open access
Locations
  • BioMed Research International (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
FICYT (GRUPIN 14-069)
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Organ Donation and Transplantation
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Ethics in Clinical Research
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Palliative Care and End-of-Life Issues
Keywords
organ donation, brain death, organ shortage, organ donation rates, legal and ethical issues, family consent
MeSH terms
Brain Death, Brain Injuries, Humans, Intensive Care Units, Tissue and Organ Procurement, Organ Transplantation

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CoChat. (2026). Citation check: Organ Donation and Elective Ventilation: A Necessary Strategy. https://app.cochat.ai/papers/10.1155/2017/7518375
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Escudero, D., Otero, J., Menéndez de León, B., & Perez-Basterrechea, M. (2017). Organ Donation and Elective Ventilation: A Necessary Strategy. BioMed Research International. https://doi.org/10.1155/2017/7518375

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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