Analysis of Risk Factors for the Development of Gestational Diabetes Mellitus in a Group of Romanian Patients
Open accessAbstract
Introduction. Gestational diabetes mellitus (GDM) is caused by numerous risk factors, the most common being old age, obesity, family history of diabetes mellitus, GDM, history of fetal macrosomia, history of polycystic ovary syndrome or treatment with particular drugs, multiple births, and certain races. The study proposed to analyze the risk factors causing GDM. Method. In the study, we included 97 pregnant women to whom there was an OGTT performed between weeks 24th and 28th of pregnancy, divided into two groups, with GDM and without GDM. The statistical analysis was performed with SPSS 26.0, the tests being statistically significant if p value < 0.05. Results. The favoring risk factors for the onset of GDM were analyzed, with statistically significant differences between the GDM group and the group without GDM related to the delivery age ( 32.39 ± 4.66 years old vs. 28.61 ± 4.71 years old), history of fetal macrosomia (13.7% vs. 0%), presence of GDM during previous pregnancies (7.8% vs. 0%), HBP before pregnancy (9.8% vs. 0%), gestational HBP (17.6% vs. 0%), glycemia value at first medical visit ( 79.37 ± 9.34 mg / dl vs. 71.39 ± 9.16 mg / dl ), and weight gain during pregnancy ( 14.61 ± 4.47 kg vs. 12.48 ± 5.87 kg ). Conclusions. Identifying the risk factors for the GDM onset has a special importance, implying an early implementation of interventional measures in order to avoid the onset of GDM and associated maternal and fetal complications.
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In Romania, IADPSG guidelines are accepted, but OGTT is performed only if risk factors for GDM are confirmed.
“Romania accepted the IADPSG guidelines for diagnosing GDM, but the OGTT test is performed only if risk factors for GDM are confirmed [166].”
From Evolution of Gestational Diabetes Mellitus across Continents in 21st Century (2022) · cites this paper as [166]
Section 2.3 says the Romanian study used IADPSG criteria to diagnose GDM, but it does not establish that Romania adopted those guidelines nationally. Sections 2.1–2.2 describe OGTT testing in the study without stating that it was performed only when GDM risk factors were confirmed. The Conclusions recommend screening women both with and without risk factors. (LLM, conf=0.85)
Experimental — accuracy not yet measuredIn Romania, Preda et al. found hypertension, gestational hypertension, history of fetal macrosomia, GDM in previous pregnancies, maternal age, and weight gain during pregnancy were significantly correlated with GDM.
“According to this study, hypertension, gestational hypertension, history of fetal macrosomia, GDM in previous pregnancies, maternal age, and weight gain during pregnancy were significantly correlated with GDM [166].”
From Evolution of Gestational Diabetes Mellitus across Continents in 21st Century (2022) · cites this paper as [166]
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Cites
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Evolution of Gestational Diabetes Mellitus across Continents in 21st Century
Dłuski, D. F., Ruszała, M., Rudziński, G., Pożarowska, K., Brzuszkiewicz, K., & Leszczyńska-Gorzelak, B. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph192315804 · Cited by 41 · see citing works
- Authors
- Preda, A., Stefan, A. G., Vladu, I. M., Fortofoiu, M.-C., Clenciu, D., Fortofoiu, M., Gheorghe, I. O., Comanescu, A. C., & Mota, M.
- Affiliations
- University of Medicine and Pharmacy of Craiova (RO)
- Department of Diabetes Nutrition and Metabolic Diseases, Calafat Municipal Hospital, Calafat, Romania
- University of Medicine and Pharmacy of Craiova, Romania
- ORCID
- Venue
- Journal of Diabetes Research
- Publisher
- Wiley
- Published
- 2022-06-02
- Volume
- 2022
- Pages
- 1-6
- ISSN
- 2314-6745 (ISSN-L)
- 2314-6753
- PMC
- PMC9184202
- OpenAlex
- W4281702038
- Cited by
- 8
- References
- 3
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 4 · 2022: 1
- FWCI
- 1.50
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Journal of Diabetes Research (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Health Sciences › Medicine › Obstetrics and Gynecology › Gestational Diabetes Research and Management
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Sciences › Medicine › Obstetrics and Gynecology › Pregnancy and preeclampsia studies
- Keywords
- gestational diabetes mellitus, risk factors, pregnancy, oral glucose tolerance test, maternal age, macrosomia, previous gestational diabetes, hypertension in pregnancy, glycemia, weight gain during pregnancy, Romanian women
- MeSH terms
- Adult, Blood Glucose, Female, Fetal Macrosomia, Humans, Pregnancy, Risk Factors, Romania, Diabetes, Gestational, Young Adult
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