Fuzzy logic in medicine and bioinformatics
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The purpose of this paper is to present a general view of the current applications of fuzzy logic in medicine and bioinformatics. We particularly review the medical literature using fuzzy logic. We then recall the geometrical interpretation of fuzzy sets as points in a fuzzy hypercube and present two concrete illustrations in medicine (drug addictions) and in bioinformatics (comparison of genomes).
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Fuzzy logic systems allow for expert rule-based reasoning that accommodates uncertainty and vagueness, which are common characteristics in psychiatric data.
“Fuzzy logic systems, by contrast, allow for expert rule-based reasoning that accommodates uncertainty and vagueness which are common characteristics in psychiatric data”
From A hybrid fuzzy logic–Random Forest model to predict psychiatric treatment order outcomes: an interpretable tool for legal decision support (2025) · cites this paper as Torres and Nieto, 2006
The Introduction says fuzzy logic handles uncertainty and vague medical descriptions, and “Fuzzy Logic in Medicine” notes imprecise patient information and difficult classification of mental disorders. Our copy does not describe expert rule-based reasoning, so that part of the claim is unsupported. (LLM, conf=0.84)
Experimental — accuracy not yet measuredFuzzy logic provides a formal framework to model uncertainty and expert knowledge, which is especially valuable in psychiatric decision-making.
“Fuzzy logic, by contrast, provides a formal framework to model uncertainty and expert knowledge, which is especially valuable in psychiatric decision-making (Torres and Nieto, 2006).”
From A hybrid fuzzy logic–Random Forest model to predict psychiatric treatment order outcomes: an interpretable tool for legal decision support (2025) · cites this paper as Torres and Nieto, 2006
The Introduction describes fuzzy logic as a formalism for medical uncertainty, and the Drug Addictions section describes an expert assigning fuzzy degrees of addiction. The Fuzzy Logic in Medicine section notes difficulties classifying mental disorders and lists related applications, but does not establish that fuzzy logic is especially valuable in psychiatric decision-making. (LLM, conf=0.82)
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Hudon, A. (2025) · Frontiers in Artificial Intelligence · doi:10.3389/frai.2025.1606250 · Cited by 3 · see citing works
“This is relevant in psychiatric contexts, where machine learning alone may miss important context-specific information that clinicians routinely interpret (Torres and Nieto, 2006).”
- Authors
- Torres, A., & Nieto, J. J.
- Affiliations
- Universidade de Santiago de Compostela (ES)
- Corresponding author
- Nieto, Juan J.
- ORCID
- Nieto, Juan J.
- Venue
- BioMed Research International
- Publisher
- Wiley
- Published
- 2006-01
- Volume
- 2006
- Issue
- 1
- Pages
- 91908-91908
- ISSN
- 1110-7243 (ISSN-L)
- 2314-6133
- 2314-6141
- PMC
- PMC1559939
- OpenAlex
- W2002317457
- Cited by
- 207
- References
- 1
- Citations by year
- 2026: 5 · 2025: 12 · 2024: 8 · 2023: 29 · 2022: 12 · 2021: 9 · 2020: 11 · 2019: 12 · 2018: 7 · 2017: 6 · 2016: 11 · 2015: 18 · 2014: 10 · 2013: 13 · 2012: 7
- FWCI
- 7.23
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- BioMed Research International (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- European fund for regional development (MTM2004–06652–C03–01)
- Ministerio de Educación y Ciencia (MTM2004–06652–C03–01)
- Xunta de Galicia (MTM2004–06652–C03–01)
- Topics
- Physical Sciences › Computer Science › Artificial Intelligence › Fuzzy Logic and Control Systems
- Physical Sciences › Computer Science › Computational Theory and Mathematics › Advanced Algebra and Logic
- Health Sciences › Health Professions › Health Information Management › Artificial Intelligence in Healthcare
- Keywords
- fuzzy logic, fuzzy sets, bioinformatics applications, drug addiction, comparative genomics
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