The DOI matches its Crossref record; 35 of the 35 references it cites were found in a registry or an index.
The Transcriptional Corepressor CtBP: A Foe of Multiple Tumor Suppressors
Open accessAbstract
CtBP1 and CtBP2 are closely related and evolutionarily conserved transcriptional corepressors. There is strong evidence linking CtBPs to tumorigenesis and tumor progression. CtBPs promote epithelial-mesenchymal transition and function as apoptosis antagonists. Also, CtBPs mediate repression of several tumor suppressor genes. Certain tumor suppressors also target CtBPs to restrain their tumor-promoting activity. Down-regulation of CtBPs mediated by some tumor suppressors results in p53-independent apoptosis and reduced tumor cell migration and invasion. The role of CtBPs in modulating the activities of different tumor suppressors is reviewed here. The results discussed here suggest that CtBPs may constitute a novel p53-independent anticancer target. [Cancer Res 2009;69(3):731–4]
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Cites
Epithelial–mesenchymal transitions in tumour progression
Thiery, J. P. (2002) · Nature Reviews Cancer · doi:10.1038/nrc822 · Cited by 6,628
Multiple loci identified in a genome-wide association study of prostate cancer
Thomas, G., Jacobs, K. B., Yeager, M., Kraft, P., Wacholder, S., Orr, N., Yu, K., Chatterjee, N., Welch, R., Hutchinson, A., et al. (2008) · Nature Genetics · doi:10.1038/ng.91 · Cited by 900
Regulation of Corepressor Function by Nuclear NADH
Zhang, Q., Piston, D. W., & Goodman, R. H. (2002) · Science · doi:10.1126/science.1069300 · Cited by 620
CtBP, an Unconventional Transcriptional Corepressor in Development and Oncogenesis
Chinnadurai, G. (2002) · Molecular Cell · doi:10.1016/s1097-2765(02)00443-4 · Cited by 523
Self-citationGuaita, S., Puig, I., Francı́, C., Garrido, M., Domı́nguez, D., Batlle, E., Sancho, E., Dedhar, S., de Herreros, A. G., & Baulida, J. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m206400200 · Cited by 499
Postigo, A. A. (2003) · The EMBO Journal · doi:10.1093/emboj/cdg226 · Cited by 387
The APC tumor suppressor counteracts β-catenin activation and H3K4 methylation at Wnt target genes
Sierra, J., Yoshida, T., Joazeiro, C. A., & Jones, K. A. (2006) · Genes & Development · doi:10.1101/gad.1385806 · Cited by 385
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Self-citationEvidence for a function of CtBP in epithelial gene regulation and anoikis
Grooteclaes, M. L., & Frisch, S. M. (2000) · Oncogene · doi:10.1038/sj.onc.1203721 · Cited by 354
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Cited by
Deconstructing repression: evolving models of co-repressor action
Perissi, V., Jepsen, K., Glass, C. K., & Rosenfeld, M. G. (2010) · Nature Reviews Genetics · doi:10.1038/nrg2736 · Cited by 532
Birts, C. N., Nijjar, S. K., Mardle, C. A., Hoakwie, F., Duriez, P. J., Blaydes, J. P., & Tavassoli, A. (2013) · Chemical Science · doi:10.1039/c3sc50481f · Cited by 85
Metadata
- Authors
- Chinnadurai, G.
- Venue
- Cancer Research
- Published
- 2009-01-29
- Volume
- 69
- Issue
- 3
- Pages
- 731-734
- ISSN
- 0008-5472 (ISSN-L)
- 1538-7445
- OpenAlex
- W2153481815
- Cited by
- 264
- References
- 35
- FWCI
- 8.06
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
