The DOI matches its Crossref record; 38 of the 38 references it cites were found in a registry or an index.
International Trends in Liver Cancer Incidence Rates
Abstract
Background: Several previous studies have documented region or country-specific liver cancer incidence trends around the world. However, no study has systematically examined the international pattern using the most recently updated incidence data from the International Agency for Research on Cancer. Methods: We examined recent trends in liver cancer incidence rates from 1993 to 2002 by joinpoint analysis for 32 cancer registries worldwide, using Cancer Incidence in Five Continents. We also examined the male to female rate ratios for these and four additional registries, based on the 1998–2002 incidence data. Results: Liver cancer incidence rates for both men and women statistically significantly increased from 1993 to 2002 for 8 of 32 cancer registries considered in the analysis. Increases were largely confined to economically developed countries of Western Europe, North America, and Oceania. In contrast, rates decreased in both men and women in 5 registries including 3 in Asia. Despite this, the incidence rates in Asian countries are twice as high as those in Africa and more than four times as high as rates in North America. Male to female rate ratios varied from 0.9 in sub-Saharan African and South American registries to 5.0 in France and Egypt. Conclusions: Liver cancer incidence rates continue to increase in some low-risk parts of the world whereas they are decreasing in some of the highest risk countries in Asia. Etiologic studies are required to further elucidate factors contributing to the divergent liver cancer incidence trends worldwide. Impact: Our description of international liver cancer incidence trends may stimulate further etiologic studies. Cancer Epidemiol Biomarkers Prev; 20(11); 2362–8. ©2011 AACR.
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Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008
Ferlay, J., Shin, H., Bray, F., Forman, D., Mathers, C., & Parkin, D. M. (2010) · International Journal of Cancer · doi:10.1002/ijc.25516 · Cited by 21,293
Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. Adults
Calle, E. E., Rodriguez, C., Walker-Thurmond, K., & Thun, M. J. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa021423 · Cited by 7,696
Permutation tests for joinpoint regression with applications to cancer rates
Kim, H.-J., Fay, M. P., Feuer, E. J., & Midthune, D. N. (2000) · Statistics in Medicine · doi:10.1002/(sici)1097-0258(20000215)19:3<335::aid-sim336>3.0.co;2-z · Cited by 6,318
Finucane, M. M., Stevens, G. A., Cowan, M. J., Danaei, G., Lin, J. K., Paciorek, C. J., Singh, G. M., Gutierrez, H. R., Lu, Y., Bahalim, A. N., et al. (2011) · The Lancet · doi:10.1016/s0140-6736(10)62037-5 · Cited by 4,050
Cancer Epidemiology and Prevention
(2006) · doi:10.1093/acprof:oso/9780195149616.001.0001 · Cited by 3,369
Rising Incidence of Hepatocellular Carcinoma in the United States
El-Serag, H. B., & Mason, A. C. (1999) · New England Journal of Medicine · doi:10.1056/nejm199903113401001 · Cited by 2,853
Perz, J. F., Armstrong, G. L., Farrington, L. A., Hutin, Y. J. F., & Bell, B. P. (2006) · Journal of Hepatology · doi:10.1016/j.jhep.2006.05.013 · Cited by 2,572
Primary liver cancer: Worldwide incidence and trends
Bosch, F. X., Ribes, J., Díaz, M., & Cléries, R. (2004) · Gastroenterology · doi:10.1053/j.gastro.2004.09.011 · Cited by 2,477
Chang, M.-H., Chen, C.-J., Lai, M.-S., Hsu, H.-M., Wu, T.-C., Kong, M.-S., Liang, D.-C., Shau, W.-Y., & Chen, D.-S. (1997) · New England Journal of Medicine · doi:10.1056/nejm199706263362602 · Cited by 1,883
Altekruse, S. F., McGlynn, K. A., & Reichman, M. E. (2009) · Journal of Clinical Oncology · doi:10.1200/jco.2008.20.7753 · Cited by 1,694
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Global cancer statistics, 2012
Torre, L. A., Bray, F., Siegel, R. L., Ferlay, J., Lortet‐Tieulent, J., & Jemal, A. (2015) · CA: A Cancer Journal for Clinicians · doi:10.3322/caac.21262 · Cited by 26,850
Self-citationGenome-wide survey of recurrent HBV integration in hepatocellular carcinoma
Sung, W.-K., Zheng, H., Li, S., Chen, R., Liu, X., Li, Y., Lee, N. P., Lee, W. H., Ariyaratne, P. N., Tennakoon, C., et al. (2012) · Nature Genetics · doi:10.1038/ng.2295 · Cited by 991
Long-term Effects of Hepatitis B Immunization of Infants in Preventing Liver Cancer
Chang, M.-H., You, S.-L., Chen, C.-J., Liu, C.-J., Lai, M.-W., Wu, T.-C., Wu, S.-F., Lee, C.-M., Yang, S.-S., Chu, H.-C., et al. (2016) · Gastroenterology · doi:10.1053/j.gastro.2016.05.048 · Cited by 258
Hughes, D. J., Duarte-Salles, T., Hybsier, S., Trichopoulou, A., Stepien, M., Aleksandrova, K., Overvad, K., Tjønneland, A., Olsen, A., Affret, A., et al. (2016) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.116.131672 · Cited by 91
Metadata
- Authors
- Center, M. M., & Jemal, A.
- Venue
- Cancer Epidemiology, Biomarkers & Prevention
- Published
- 2011-11-01
- Volume
- 20
- Issue
- 11
- Pages
- 2362-2368
- ISSN
- 1055-9965 (ISSN-L)
- 1538-7755
- OpenAlex
- W2126453212
- Cited by
- 309
- References
- 38
- FWCI
- 8.13
- Type
- journal article
- Language
- en
- Open access
- closed
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