Psychological distress after a positive fecal occult blood test result among members of an integrated healthcare delivery system
Open accessAbstract
Background: Colorectal cancer screening (CRCS) reduces morbidity and mortality; however, the positive benefits might be partially offset by long-term distress following positive screening results. We examined relationships among colorectal cancer–specific worry and situational anxiety after positive fecal occult blood tests [FOBT (+)] compared with receipt of negative results. Methods: Of note, 2,260 eligible members of Group Health, an integrated healthcare delivery system, completed baseline surveys and received FOBT screening kits, with 1,467 members returning the kits. We matched FOBT (+) patients (n = 55) 1:2 on age and sex with FOBT (−) respondents (n = 110). Both groups completed follow-up surveys at 7 to 14 days and 4 months after screening. We assessed situational anxiety (State-Trait Anxiety Inventory, STAI), colorectal cancer worry frequency, and mood disturbance. Results: Mean age was 59 years, and majority were women (62%) and White (89%). After adjusting for age, sex, and baseline worry, at 7 to 14 days after screening, the FOBT (+) group was 3.82 [95% confidence interval (CI), 1.09–13.43] times more likely to report colorectal cancer–related mood disturbances and significantly higher mean STAI scores than the FOBT (−) group (mean = 38.8 vs. 30.9; P = 0.007). At 4-month posttest, mood disturbances and situational anxiety seemed to drop to baseline levels for FOBT (+). No colon cancer worry frequency was observed. Conclusions: FOBT (+) results are associated with short-term situational anxiety and colorectal cancer–specific mood disturbances. Impact: Distress from FOBT (+) results declined to near-baseline levels by 4 months. Additional studies are needed to clarify the relationship between long-term distress and follow-up colonoscopy. Cancer Epidemiol Biomarkers Prev; 23(1); 154–9. ©2013 AACR.
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Cites
Eysenck, H. J. (1985) · Behaviour Research and Therapy · doi:10.1016/0005-7967(85)90087-7 · Cited by 32,026 · see citing works
“Stress: appraisal and coping,”
Folkman, S. (2013) · Encyclopedia of Behavioral Medicine · doi:10.1007/978-1-4419-1005-9_215 · Cited by 27,833 · see citing works
(1970) · Cited by 24,983 · see citing works
Stress, Appraisal, and Coping. New York, NY: Springer;
Lazarus, R. M., & Folkman, S. (1984) · Medical Entomology and Zoology · Cited by 3,473 · see citing works
Carver, C. S., Pozo-Kaderman, C., Harris, S. D., Noriega, V., Scheier, M. F., Robinson, D. S., Ketcham, A. S., Moffat, F. L., & Clark, K. C. (1993) · Journal of Personality and Social Psychology · doi:10.1037//0022-3514.65.2.375 · Cited by 1,739 · see citing works
Carver, C. S., Pozo, C., Harris, S. D., Noriega, V., Scheier, M. F., Robinson, D. S., Ketcham, A. S., Moffat, F. L., & Clark, K. C. (1993) · Journal of Personality and Social Psychology · doi:10.1037/0022-3514.65.2.375 · Cited by 1,228 · see citing works
The relative efficacy of avoidant and nonavoidant coping strategies: A meta-analysis.
Suls, J. M., & Fletcher, B. (1985) · Health Psychology · doi:10.1037//0278-6133.4.3.249 · Cited by 1,224 · see citing works
The relative efficacy of avoidant and nonavoidant coping strategies: A meta-analysis.
Suls, J. M., & Fletcher, B. (1985) · Health Psychology · doi:10.1037/0278-6133.4.3.249 · Cited by 885 · see citing works
Taylor, S. E., Kemeny, M. E., Aspinwall, L. G., Schneider, S. G., Rodriguez, R., & Herbert, M. (1992) · Journal of Personality and Social Psychology · doi:10.1037//0022-3514.63.3.460 · Cited by 565 · see citing works
Systematic Review: The Long-Term Effects of False-Positive Mammograms
Brewer, N. T., Salz, T., & Lillie, S. E. (2007) · Annals of Internal Medicine · doi:10.7326/0003-4819-146-7-200704030-00006 · Cited by 459 · see citing works
Taylor, S. E., Kemeny, M. E., Aspinwall, L. G., Schneider, S. G., Rodriguez, R., & Herbert, M. (1992) · Journal of Personality and Social Psychology · doi:10.1037/0022-3514.63.3.460 · Cited by 415 · see citing works
Short- and long-term anxiety and depression in women recalled after breast cancer screening
Lampic, C., Thurfjell, E., Bergh, J. C. S., & Sjödén, P. (2001) · European Journal of Cancer · doi:10.1016/s0959-8049(00)00426-3 · Cited by 157 · see citing works
Aro, A. R., Absetz, S. P., van Elderen, T., van der Ploeg, E., & van der Kamp, L. J. T. (2000) · European Journal of Cancer · doi:10.1016/s0959-8049(00)00065-4 · Cited by 131 · see citing works
Describing and predicting psychological distress after colorectal cancer
Lynch, B. M., Steginga, S. K., Hawkes, A. L., Pakenham, K. I., & Dunn, J. C. (2008) · Cancer · doi:10.1002/cncr.23300 · Cited by 124 · see citing works
Perceived control reduces emotional stress in patients with heart failure
Dracup, K., Westlake, C. A., Erickson, V., Moser, D. K., Caldwell, M. L., & Hamilton, M. A. (2003) · The Journal of Heart and Lung Transplantation · doi:10.1016/s1053-2498(02)00454-0 · Cited by 111 · see citing works
on behalf of the TOMBOLA group, Gray, N., Sharp, L., Cotton, S. C., Masson, L. F., Little, J., Walker, L. G., Avis, M., Philips, Z., Russell, I. T., et al. (2006) · British Journal of Cancer · doi:10.1038/sj.bjc.6603086 · Cited by 103 · see citing works
McNaughton‐Collins, M., Fowler, F. J., Caubet, J.-F., et al. (2004) · The American Journal of Medicine · doi:10.1016/j.amjmed.2004.06.036 · Cited by 102 · see citing works
Trask, P., Paterson, A. G., Wang, C., Hayasaka, S., Milliron, K., Blumberg, L., Gonzalez, R., Murray, S., & Merajver, S. (2001) · Psycho-Oncology · doi:10.1002/pon.510 · Cited by 81 · see citing works
Communicating breast cancer risks to women using different formats.
Lipkus, I. M., Klein, W. M. P., & Rimer, B. K. (2001) · PubMed · Cited by 77 · see citing works
Health Perceptions in Patients Who Undergo Screening and Workup for Prostate Cancer
Katz, D. A., Jarrard, D. F., McHorney, C. A., Hillis, S. L., Wiebe, D. A., & Fryback, D. G. (2007) · Urology · doi:10.1016/j.urology.2006.09.059 · Cited by 61 · see citing works
Cohen, M. W. (2002) · Behavioral Medicine · doi:10.1080/08964280209596394 · Cited by 58 · see citing works
Hellsten, C., Sjöström, K., & Lindqvist, P. G. (2007) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/j.1471-0528.2007.01609.x · Cited by 58 · see citing works
Psychiatric morbidity and screening for colorectal cancer
Parker, M. A., Robinson, M. H., Scholefield, J. H., & Hardcastle, J. D. (2002) · Journal of Medical Screening · doi:10.1136/jms.9.1.7 · Cited by 57 · see citing works
Factors associated with intentions to adhere to colorectal cancer screening follow-up exams
Zheng, Y.-F., Saito, T., Takahashi, M., Ishibashi, T., & Kai, I. (2006) · BMC Public Health · doi:10.1186/1471-2458-6-272 · Cited by 52 · see citing works
Experiences of patients with false positive results from colorectal cancer screening.
Mant, D., Fitzpatrick, R., Hogg, A., et al. (1990) · PubMed · Cited by 49 · see citing works
Adherence to Mammography and Colorectal Cancer Screening in Women 50–80 Years of Age
O'Donnell, S., Goldstein, B. H., DiMatteo, M. R., et al. (2010) · Women s Health Issues · doi:10.1016/j.whi.2010.04.002 · Cited by 44 · see citing works
Brasso, K., Ladelund, S., Frederiksen, B., & Jørgensen, T. (2010) · Scandinavian Journal of Gastroenterology · doi:10.3109/00365521.2010.485355 · Cited by 35 · see citing works
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Depression and anxiety are common among patients with cirrhosis
Hernaez, R., Kramer, J. R., Khan, A., Phillips, J., McCallister, K., Chaffin, K., Hernandez, A. P., Fullington, H., Ortiz, C., Blackwell, J.-M., et al. (2022) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2020.08.045 · Cited by 77 · see citing works
- Authors
- Laing, S. S., Bogart, A., Chubak, J., Fuller, S., & Green, B. B.
- Affiliations
- University of Washington (US)
- Kaiser Permanente Washington Health Research Institute (US)
- Corresponding author
- Laing, Sharon S.
- Venue
- Cancer Epidemiology, Biomarkers & Prevention
- Published
- 2014-01-01
- Volume
- 23
- Issue
- 1
- Pages
- 154-159
- ISSN
- 1055-9965 (ISSN-L)
- 1538-7755
- PMC
- PMC3947142
- OpenAlex
- W2128132717
- Cited by
- 38
- References
- 27
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 1 · 2023: 7 · 2022: 4 · 2021: 2 · 2020: 2 · 2019: 1 · 2018: 7 · 2017: 3 · 2016: 4 · 2015: 2 · 2014: 1
- FWCI
- 1.25
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Cancer Epidemiology Biomarkers & Prevention (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- University of Washington Tacoma Digital Commons (University of Washington Tacoma) (submittedVersion)
- Funders
- National Cancer Institute (R01CA121125)
- Topics
- Health Sciences › Medicine › Oncology › Colorectal Cancer Screening and Detection
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Health Sciences › Medicine › Oncology › Colorectal Cancer Surgical Treatments
- Keywords
- fecal occult blood test, positive screening results, psychological distress, state anxiety, mood disturbance, colorectal cancer screening, integrated health system, Group Health, follow-up colonoscopy
- MeSH terms
- Anxiety, Delivery of Health Care, Female, Humans, Male, Middle Aged, Occult Blood, Surveys and Questionnaires, Reagent Kits, Diagnostic, Colorectal Neoplasms, Delivery of Health Care, Integrated, Early Detection of Cancer
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