An LXR Agonist Promotes Glioblastoma Cell Death through Inhibition of an EGFR/AKT/SREBP-1/LDLR–Dependent Pathway

Cited by (451)

Items 401–451 of 451

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   Ryan Michael Sheehy, Raymond J. Hohl, Rory Alan Fisher · 2015
2. Effect of a Synthetic Liver X Receptor Agonist TO901317 on Cholesterol Concentration in Goose Primary Hepatocytes
   Fang He, Chunchun Han, Dandan Liu · 2014 · Italian Journal of Animal Science
3. METABOLOMICS AND PROTEOMICS STUDIES OF BRAIN TUMORS - A CHEMOMETRIC BIOINFORMATICS APPROACH
   Lina Mörén · 2015 · KTH Publication Database DiVA (KTH Royal Institute of Technology)
4. Characterizing and analyzing disease-related omics data using network modeling approaches
   Chunjing Wang · 2014 · Illinois Digital Environment for Access to Learning and Scholarship (University of Illinois at Urbana-Champaign)
5. NSDHL Depletion Promotes Cellular Senescence in Mouse Embryonic Fibroblasts
   Linara Gabitova, Igor A. Astsaturov · 2015 · DOAJ (DOAJ: Directory of Open Access Journals)
6. A expressão de receptores de LDL em membrana celular de focos de endometriose profunda para viabilização do uso de nanoemulsão lipídica carreadora de droga antiproliferativa
   Luciano Gibran · 2016
7. SREBP1 regulates mitochondrial metabolism in oncogenic KRAS expressing NSCLC
   Christian Felipe Ruiz, Emily D. Montal, John D. Haley, John D. Haley · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
8. Nutriments et cancer : alliés ou ennemis ?
   Fabienne Guillaumond, Sophie Vasseur · 2020 · Cahiers de Nutrition et de Diététique
9. Glioblastoma Multiforme Metabolism: Fuel to the Flame
   Preethi Sridharan · 2016 · Annals of SBV
10. DELINEATING THE ROLE OF FATTY ACID METABOLISM TO IMPROVE THERAPEUTIC STRATEGIES FOR COLORECTAL CANCER
    James Drury · 2021 · UKnowledge (University of Kentucky)
11. STUB1-SMYD2 Axis Regulated Drug Resistance in Glioma cells
    Kailing Pan, Bin Hu, Lude Wang · 2021 · Research Square
12. Cómo afrontar el comportamiento irracional del otro
    Ana Ma Martín Almagro · 2012 · Diálogo: Familia Colegio
13. ナタネとレンゲのすき込みが夏ソバの生育・収量に及ぼす影響(日本作物学会四国支部第44回講演会講演要旨)
    裕 佐藤, 秀樹 杉本, 匡彦 池原 · 2007 · 日本作物学会四国支部会報
14. Inhibition of lipogenesis and induction of apoptosis by valproic acid in prostate cancer cells via the C/EBPα/SREBP-1 pathway
    Bo Pang, Juanjuan Zhang, Jihong Yuan · 2020
15. Inhibition of lipogenesis and induction of apoptosis by valproic acid in prostate cancer cells via the C/EBPα/SREBP-1 pathway
    Bo Pang, Juanjuan Zhang, Jihong Yuan · 2020
16. Inhibition of lipogenesis and induction of apoptosis by valproic acid in prostate cancer cells via the C/EBPα/SREBP-1 pathway
    Bo Pang, Juanjuan Zhang, Jihong Yuan · 2020
17. STUB1-SMYD2 Axis Regulated Drug Resistance in Glioma cells
    Kailing Pan, Bin Hu, Lude Wang · 2022 · Research Square
18. Data from Induction of Synthetic Lethality by Activation of Mitochondrial ClpP and Inhibition of HDAC1/2 in Glioblastoma
    Trang Thi Thu Nguyen, Enyuan Shang, Salveena Schiffgens, Consuelo Torrini, Chang Shu, Hasan Orhan Akman, Varun V. Prabhu, Joshua E. Allen, Mike‐Andrew Westhoff, Georg Karpel‐Massler et al. · 2023
19. Data from Induction of Synthetic Lethality by Activation of Mitochondrial ClpP and Inhibition of HDAC1/2 in Glioblastoma
    Trang Thi Thu Nguyen, Enyuan Shang, Salveena Schiffgens, Consuelo Torrini, Chang Shu, Hasan Orhan Akman, Varun V. Prabhu, Joshua E. Allen, Mike‐Andrew Westhoff, Georg Karpel‐Massler et al. · 2023
20. Data from PPARδ Reprograms Glutamine Metabolism in Sorafenib-Resistant HCC
    Mi Jin Kim, Yeon‐Kyung Choi, Soo‐Young Park et al. · 2023
21. Biology of Cancer
    Rawiah Alsiary, Hanadi A. Katouah, Hiba Saeed A. Bagader Al-Amodi, Mashael Al-Toub · 2023 · BENTHAM SCIENCE PUBLISHERS eBooks
22. SREBF1 is a Potential Prognostic and Immunological Biomarker in Pan-Cancer
    Xiaoyan Zhang, Lei Pu, Pu Cheng, Yuqiang Li · 2024 · Research Square
23. Unraveling the Potential Pathogenic Role of Squalene Synthase (SQS) in Lung Cancer Using Enzyme Inhibitors as Molecular Tools
    Theodora Katavati, Filippos Panteleimon Chatzipieris, Christiana Magkrioti, Elli-Anna Stylianaki, Emmanouil Aerakis, Sofia Grammenoudi, Maria Tsoumakidou, Vassilis Aidinis, Alexios N. Matralis, Angeliki P. Kourounakis · 2025 · ACS Medicinal Chemistry Letters
24. Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism
    Adrien M. Vaquié, D. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhao-Yang Xu, J. Stockley, Laura Morcom, Diana Gold Diaz, G. Girdler, Rachel V. Seear et al. · 2025 · Molecular Oncology
25. Mechanisms of multidrug resistance in cancer
    Pratik Pathade, Shweta Nagre, Rashmi Rana · 2025 · Elsevier eBooks
26. Additional file 8 of Identification of lipidomic profiles associated with drug-resistant prostate cancer cells
    Lishann M. Ingram, Morgan C. Finnerty, Maryam Mansoura · 2021 · Figshare
27. Additional file 1 of Anlotinib affects systemic lipid metabolism and induces lipid accumulation in human lung cancer cells
    Zhu, Zhongling, Xu, Shan, Jing Ren · 2023 · Figshare
28. Additional file 7 of Identification of lipidomic profiles associated with drug-resistant prostate cancer cells
    Lishann M. Ingram, Morgan C. Finnerty, Maryam Mansoura · 2021 · Figshare
29. Additional file 2 of Anlotinib affects systemic lipid metabolism and induces lipid accumulation in human lung cancer cells
    朱仲玲, Xu, Shan, Jing Ren · 2023 · Figshare
30. Additional file 1 of Therapeutic protein PAK restrains the progression of triple negative breast cancer through degrading SREBP-1 mRNA
    Hu, Pan, Peiyi Zhou, Tieyun Sun · 2023 · Figshare
31. Additional file 1 of How cancer cells remodel lipid metabolism: strategies targeting transcription factors
    Jeong, Do-Won, Seulbee Lee, Chun, Yang-Sook · 2021 · Figshare
32. A therapeutic approach of LC-MS characterised MFER-Mc against alcohol and NDEA induced hepatocellular carcinoma activity through LXR-α, LXR-β and HMG-CoA pathway: an in-silico, in-vitro and in-vivo study
    Shashi Ranjan, Priyashree Sunita, Shakti Prasad Pattanayak · 2025 · Medical Oncology
33. Tumor-associated astrocytes augment cholesterol synthesis to support glioblastoma growth through alternatively spliced QKI isoforms
    Runxin Wu, Xiaozhou Yu, Xiao Song et al. · 2026 · Neuro-Oncology
34. Treatment-Resilient Lipid Remodeling Defines Temozolomide Resistance and Failure of Simvastatin Sensitization in Glioblastoma
    Kianoosh Naghibzadeh, Hyunjin Cho, Amir Barzegar Behrooz et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
35. Etude du mécanisme d'action d'un onco-métabolite impliqué dans la prolifération des cancers du sein triple-négatifs
    Arnaud Mallinger · 2019
36. Identification de nouveaux agents anticancéreux issus du cholestérol : Application à la thérapie métabolique du glioblastome
    Khouloud Sassi · 2021
37. Conception, synthèse et évaluation de vecteurs peptidiques qui facilitent la délivrance de siARN thérapeutiques dans les organes
    B. Broc · 2023 · theses.fr (ABES)
38. Elucidating the Vulnerability of Glioblastoma Stem-like Cells to Lysosomal Dysfunctions
    Clément Maghe · 2023
39. RORα: a critical nexus in the crosstalk between cholesterol metabolism and macrophage polarization
    Dengju Li, Guangxian Liu, Xiangdong Wen, Guojiang Zhang, Kaixuan Liu, Lin Yuan, Bingbing Yu, Senbo An · 2026 · Frontiers in Immunology
40. Cholesteryl Ester as a Prognostic Biomarker In IDH-wildtype Glioblastoma
    nana wang, JieJun Wang, Jianlin Liu, Jinqi Zou, Bin Yang, P Wang, Nan Ji, Shuhua Yue · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
41. Oncogenic drivers in cancer: Genomic alterations, molecular mechanisms, and targeted therapeutic strategies
    Sudarshan Rajput, Amrapali Mhaiskar, Ujashkumar A. Shah, Shaktipal Patil · 2026 · Pharmacological Research - Reports
42. Machine learning-based discovery of GW3965 as a therapeutic compound against invasive emm92-type group A Streptococcus
    Lillie M. Powell, Megan E. Grund, Wenxian Shi, Soo Jeon Choi, Keilly Zelaya, Sharan Kumar Reddy Bobbala, Werner Geldenhuys, Mariette Barbier, P. Rocco LaSala, Sławomir Łukomski · 2026 · npj Antimicrobials and Resistance
43. Dual SYK-HDAC Inhibitor Elicits Striking Efficacy against Acute Myeloid Leukemia: Rational Design, Synthesis, and Biological Evaluation
    Anshul Mishra, Wen-Bin Yang, Tsu-Shao Liu, Amandeep Thakur, Ajmer Singh Grewal, Jacek Marczyk, Giovanni Stelitano, Ram Sharma, Mandeep Rana, Gurpreet Singh et al. · 2026 · Journal of Medicinal Chemistry
44. A MYCN–GAL–SREBP1 lipogenic axis drives proliferation in silent corticotroph adenomas
    Changxi Han, Junchen Wu, Jing Xie, Li J, Zongze He, Bo Zhang, Yihan Dong, Qiuyue Fang, Jingwei Ye, Zhuoyi Tang et al. · 2026 · Neuro-Oncology
45. NRP1 Promotes Chronic Lymphocytic Leukemia Progression by Regulating Lipid Synthesis via the EGFR/Akt/SREBP-1 Pathway
    F. Jia, K. Xiang · 2026 · Molecular Biology
46. Fatty Acid Metabolism Rewires Glioblastoma Progression and Treg-Mediated Immune Resistance
    Nowreen Islam Chowdhury, Heba A. Ewida, Mahmoud Salama Ahmed, Heidi Villalba · 2026 · Cancers
47. The interplay between lipid metabolism, cancer progression and anti-cancer immunity
    Choong‐Hyun Koh, Yoosun Lee, Il‐Kyu Kim, Yeonseok Chung · 2026 · Experimental & Molecular Medicine
48. Metabolic reprogramming and drug resistance in hepatocellular carcinoma: The emerging role of SREBP2-driven cholesterol metabolism
    Veerababu Nagati, Swathi Tenugu, Miguel Salazar, Manish Kumar Tripathi · 2026 · Drug Discovery Today
49. Curculigoside suppresses glioblastoma progression through the EGFR/MMP2 axis: evidence from network pharmacology and experimental validation
    Jiawen Han, Zhanchuan Ma, Shan Lin, Wei Wu · 2026 · Bioorganic Chemistry
50. Advances in single-cell and spatial multi-omics for deciphering the mechanisms of pan-organ metastasis in breast cancer
    Yang Qu, Juan Sun, Zihao Wang, Qiang Sun, Yidong Zhou · 2026 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
51. Combination of ALK2 and cholesterol targeting agents exploits linked genetic and metabolic dependencies in diffuse midline glioma
    Rebecca Rogers, Alan G. Mackay, Yura Grabovska, Diana Carvalho, Claire Dobinson, Anna Burford, Valeria Molinari, Rita Pereira, Laura Bevington, Ruth Ruddle et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)