Cytochrome P450 3A expression in the human fetal liver: evidence that CYP3A5 is expressed in only a limited number of fetal livers

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

Bradford, M. M. (1976) · Analytical Biochemistry · doi:10.1016/0003-2697(76)90527-3 · Cited by 255,302 · see citing works

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

LAEMMLI, U. K. (1970) · Nature · doi:10.1038/227680a0 · Cited by 249,961 · see citing works

P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature

Nelson, D. R., Koymans, L. M. H., Kamataki, T., Stegeman, J. J., Feyereisen, R., Waxman, D. J., Waterman, M. R., Gotoh, O., Coon, M. J., Estabrook, R. W., et al. (1996) · Pharmacogenetics · doi:10.1097/00008571-199602000-00002 · Cited by 2,946 · see citing works

Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians

Shimada, T., Yamazaki, H., Mimura, M., Inui, Y., & Guengerich, F. P. (1994) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)22379-5 · Cited by 2,785 · see citing works

An Orphan Nuclear Receptor Activated by Pregnanes Defines a Novel Steroid Signaling Pathway

Kliewer, S. A., Moore, J. T., Wade, L., Staudinger, J. L., Watson, M. A., Jones, S. A., McKee, D. D., Oliver, B. B., Willson, T. M., Zetterström, R. H., et al. (1998) · Cell · doi:10.1016/s0092-8674(00)80900-9 · Cited by 1,534 · see citing works

The Human Hepatic Cytochromes P450 Involved in Drug Metabolism

Wrighton, S. A., & Stevens, J. C. (1992) · Critical Reviews in Toxicology · doi:10.3109/10408449209145319 · Cited by 948 · see citing works

SXR, a novel steroid and xenobioticsensing nuclear receptorPreprint

Blumberg, B., Sabbagh, W., Juguilon, H., Bolado, J., van Meter, C. M., Ong, E. S., & Evans, R. M. (1998) · Genes & Development · doi:10.1101/gad.12.20.3195 · Cited by 912 · see citing works

Identification of a human nuclear receptor defines a new signaling pathway for CYP 3 A induction

Bertilsson, G., Heidrich, J., Svensson, K., Åsman, M., Jendeberg, L., Sydow‐Báckman, M., OHLSSON, R. I., Postlind, H., Blomquist, P., & Berkenstam, A. L. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.21.12208 · Cited by 873 · see citing works

Enzyme induction in the cytochrome P-450 system

Okey, A. B. (1990) · Pharmacology & Therapeutics · doi:10.1016/0163-7258(90)90030-6 · Cited by 628 · see citing works

MOLECULAR MECHANISMS OF GENETIC POLYMORPHISMS OF DRUG METABOLISM

Meyer, U., & Zanger, U. M. (1997) · The Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.37.1.269 · Cited by 549 · see citing works

Expression of CYP3A in the Human Liver — Evidence that the Shift between CYP3A7 and CYP3A4 Occurs Immediately After Birth

Lacroix, D. A., Sonnier, M., Moncion, A., Chéron, G., & Cresteil, T. (1997) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1997.00625.x · Cited by 537 · see citing works

RESPONSE: Re: Modification of Clinical Presentation of Prostate Tumors by a Novel Genetic Variant in CYP3A4

Amirimani, B., Walker, A., Weber, B., & Rebbeck, T. R. (1999) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/91.18.1588 · Cited by 462 · see citing works

Studies on the expression and metabolic capabilities of human liver cytochrome P450IIIA5 (HLp3).

Wrighton, S. A., Brian, W., Sari, M., Iwasaki, M., Guengerich, F. P., Raucy, J. L., Molowa, D. T., & VandenBranden, M. R. (1990) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)09441-6 · Cited by 399 · see citing works

Association of CYP 3 A 4 genotype with treatment-related leukemia

Felix, C. A., Walker, A. H., Lange, B. J., Williams, T. M., Winick, N. J., Cheung, N. V., Lovett, B. D., Nowell̀, P. C., Blair, I. A., & Rebbeck, T. R. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.22.13176 · Cited by 310 · see citing works

Selective expression of cytochrome P450 CYP3A mRNAs in embryonic and adult human liver

Schuetz, J. D., Beach, D. L., & Guzelian, P. S. (1994) · Pharmacogenetics · doi:10.1097/00008571-199402000-00002 · Cited by 275 · see citing works

Characterization of microsomal cytochrome P450 enzymes involved in the oxidation of xenobiotic chemicals in human fetal liver and adult lungs.

Shimada, T., Yamazaki, H., Mimura, M., Wakamiya, N., Ueng, Y., Guengerich, F. P., & Inui, Y. (1996) · PubMed · Cited by 244 · see citing works

Xenobiotic-metabolizing cytochrome P450 enzymes in the human feto-placental unit: role in intrauterine toxicity

Hakkola, J., Pelkonen, O., Pasanen, M., & Raunio, H. (1998) · Critical Reviews in Toxicology · doi:10.1080/10408449891344173 · Cited by 229 · see citing works

Expression of xenobiotic-metabolizing cytochrome P450 forms in human adult and fetal liver

Hakkola, J., Pasanen, M., Purkunen, R., Saarikoski, S., Pelkonen, O., Mäenpää, J., Rane, A., & Raunio, H. (1994) · Biochemical Pharmacology · doi:10.1016/0006-2952(94)90223-2 · Cited by 206 · see citing works

Fetus-specific expression of a form of cytochrome P-450 in human livers

Komori, M., Nishio, K., Kitada, M., et al. (1990) · Biochemistry · doi:10.1021/bi00470a024 · Cited by 203 · see citing works

Regulation of human liver cytochromes P-450 in family 3A in primary and continuous culture of human hepatocytes

Schuetz, E. G., Schuetz, J. D., Strom, S. C., et al. (1993) · Hepatology · doi:10.1002/hep.1840180535 · Cited by 185 · see citing works

P-450 HFLa, a form of cytochrome P-450 purified from human fetal livers, is the 16 alpha-hydroxylase of dehydroepiandrosterone 3-sulfate.

Kitada, M., Kamataki, T., Itahashi, K., Rikihisa, T., & Kanakubo, Y. (1987) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)76460-6 · Cited by 162 · see citing works

Expression and Localization of CYP3A4 and CYP3A5 in Human Lung

Anttila, S. L., Hukkanen, J., Hakkola, J., et al. (1997) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/ajrcmb.16.3.9070608 · Cited by 155 · see citing works

The presence of a monooxygenase system in human fetal liver microsomes

Yaffe, S. J., Rane, A., Sjöqvist, F., et al. (1970) · Life Sciences · doi:10.1016/0024-3205(70)90038-x · Cited by 146 · see citing works

Purification and properties of cytochrome P-450 from homogenates of human fetal livers

Kitada, M., Kamataki, T., Itahashi, K., et al. (1985) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(85)90383-2 · Cited by 137 · see citing works

Development of a Comprehensive Panel of Antibodies against the Major Xenobiotic Metabolising Forms of Cytochrome P450 in Humans

Edwards, R. J., Adams, D. A., Watts, P. S., Davies, D. S., & Boobis, A. R. (1998) · Biochemical Pharmacology · doi:10.1016/s0006-2952(98)00033-1 · Cited by 133 · see citing works

Developmental Expression of Cytochrome P450 Enzymes in Human Liver

Hakkola, J., Tanaka, E., & Pelkonen, O. (1998) · Pharmacology & Toxicology · doi:10.1111/j.1600-0773.1998.tb01427.x · Cited by 128 · see citing works

The antibiotic rifampicin is a nonsteroidal ligand and activator of the human glucocorticoid receptor

Calleja, C., Pascussi, J., Mani, J. C., Maurel, P., & Vilarem, M. (1998) · Nature Medicine · doi:10.1038/nm0198-092 · Cited by 109 · see citing works

Functional cytochrome P4503A isoforms in human embryonic tissues: expression during organogenesis.

Yang, H., Lee, Q. P., Rettie, A. E., & Juchau, M. R. (1994) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)09834-7 · Cited by 86 · see citing works

Detection of a CYP3A5 Allelic Variant: A Candidate for the Polymorphic Expression of the Protein?

Jounaïdi, Y., Hyrailles, V., Gervot, L., et al. (1996) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1996.0618 · Cited by 81 · see citing works

The 1992 Bernard B. Brodie Award Lecture. Bioactivation and detoxication of toxic and carcinogenic chemicals.

Guengerich, F. P. (1993) · Drug Metabolism and Disposition · doi:10.1016/s0090-9556(25)07309-x · Cited by 80 · see citing works

The Fetal Specific GeneCYP3A7Is Inducible by Rifampicin in Adult Human Hepatocytes in Primary Culture

Greuet, J., Pichard, L., Bonfils, C., et al. (1996) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1996.1231 · Cited by 64 · see citing works

Cytochrome P450 in Human Fetal Liver: Significance and Fetal-Specific Expresson

Kitada, M., & Kamataki, T. (1994) · Drug Metabolism Reviews · doi:10.3109/03602539409029800 · Cited by 64 · see citing works

Rapid construction of deleted DNA fragments for use as internal standards in competitive PCR.Preprint

Jin, C., Mata, M. M., & Fink, D. J. (1994) · Genome Research · doi:10.1101/gr.3.4.252 · Cited by 58 · see citing works

Cytochrome-P450-Dependent Biotransformation of Xenobiotics in Human and Rodent Embryonic Tissues

Juchau, M. R., Boutelet-Bochan, H., & Huang, Y.-W. (1998) · Drug Metabolism Reviews · doi:10.3109/03602539808996324 · Cited by 50 · see citing works

Quantification of Multiple Human Cytochrome P450 mRNA Molecules Using Competitive Reverse Transcriptase-PCR

Andersen, M. R., Farin, F. M., & Omiecinski, C. J. (1998) · DNA and Cell Biology · doi:10.1089/dna.1998.17.231 · Cited by 46 · see citing works

Reannealing of artificial heteroduplexes generated during PCR-mediated genetic isotyping

Wenger, R. H., & Nielsen, P. J. (1991) · Trends in Genetics · doi:10.1016/0168-9525(91)90430-x · Cited by 16 · see citing works

Significantly Increased Cortisol Secretion in Normal Adrenocortical Cells Transfected with K-ras Mutants Derived from Human Functional Adrenocortical Tumors

Hsu, C., Yang, Y., Lian, S.-T., et al. (2001) · DNA and Cell Biology · doi:10.1089/104454901750219116 · Cited by 7 · see citing works

Reannealing of artificial heteroduplexes generated during PCR-mediated genetic isotyping

(1991) · Trends in Genetics · doi:10.1016/0168-9525(91)90109-4 · Cited by 3 · see citing works

Human steroid biosynthesis, metabolism and excretion are differentially reflected by serum and urine steroid metabolomes: a comprehensive review

Schiffer, L., Barnard, L., Baranowski, E. S., Gilligan, L. C., Taylor, A. E., Arlt, W., Shackleton, C. H. L., & Storbeck, K.-H. (2019) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2019.105439 · Cited by 450 · see citing works

Variability of CYP3A7 expression in human fetal liver

Leeder, J. S., Gaedigk, R., Marcucci, K. A., Gaedigk, A., Vyhlidal, C. A., Schindel, B. P., & Pearce, R. E. (2005) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.105.086504 · Cited by 136 · see citing works

Quantitative Prediction of CYP3A4‐ and CYP3A5‐Mediated Drug Interactions

Guo, Y., Lucksiri, A., Dickinson, G. L., et al. (2019) · Clinical Pharmacology & Therapeutics · doi:10.1002/cpt.1596 · Cited by 22 · see citing works

Immunochemical detection of cytochrome P450 enzymes in small intestine microsomes of male and female untreated juvenile cynomolgus monkeys

Uehara, S., Murayama, N., Nakanishi, Y., et al. (2014) · Xenobiotica · doi:10.3109/00498254.2014.895882 · Cited by 13 · see citing works

Expression of CYP3A4, CYP3A5 and CYP3A7 in human duodenal tissue

Kivistö, K. T., Bookjans, G., Fromm, M. F., Griese, E., Münzel, P., & Kroemer, H. K. (1996) · British Journal of Clinical Pharmacology · doi:10.1046/j.1365-2125.1996.42615.x · Cited by 106 · see citing works

Does sex influence proximal small intestinal CYP3A or P-GP expression?

PAINE, M., Ludington, S. S., CHEN, M., et al. (2005) · Clinical Pharmacology & Therapeutics · doi:10.1016/j.clpt.2004.11.011 · Cited by 1 · see citing works

Ethnic differences between Japanese and Caucasians in the expression levels of mRNAs for CYP3A4, CYP3A5 and CYP3A7: lack of co-regulation of the expression of CYP3A in Japanese livers

Yamaori, S., Yamazaki, H., Iwano, S., et al. (2005) · Xenobiotica · doi:10.1080/00498250400021796 · Cited by 55 · see citing works