The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Double–Blind, Crossover Comparison of 3 mg Apomorphine SL with Placebo and with 4 mg Apomorphine SL in Male Erectile Dysfunction
Abstract
Objective To establish the efficacy and safety of a fixed, 3-mg dose of apomorphine SL compared with placebo, and to compare 3 mg with 4 mg apomorphine SL in patients with erectile dysfunction. Methods This randomized, double-blind, crossover study included 296 heterosexual men with ED of various etiologies and severities. Two crossover groups were evaluated separately: 3 mg apomorphine SL vs. placebo (n = 194), and 3 vs. 4 mg apomorphine SL (n = 102). The primary efficacy variable was the percentage of attempts resulting in erections firm enough for intercourse; additional variables included the percentage of attempts resulting in intercourse and time to erection. Partner assessments were also analyzed. Results 3 mg apomorphine SL was significantly more effective than placebo (p Conclusions 3 mg apomorphine SL was significantly more effective than placebo and comparable to 4 mg, while offering an improved risk-benefit ratio.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Efficacy rates (erections hard enough for intercourse) range from 28.5% to 55% [27].”
From Erectile dysfunction and its pharmacology: An overview (2017) · cites this paper as [27]
Citations
Cites
Rosen, R. C., Riley, A., Wagner, G., Osterloh, I. H., Kirkpatrick, J., & Mishra, A. (1997) · Urology · doi:10.1016/s0090-4295(97)00238-0 · Cited by 5,849
Impotence and Its Medical and Psychosocial Correlates: Results of the Massachusetts Male Aging Study
Feldman, H. A., Goldstein, I., Hatzichristou, D. G., Krane, R. J., & McKinlay, J. B. (1994) · Journal of Urology · doi:10.1016/s0022-5347(17)34871-1 · Cited by 5,074
THE EPIDEMIOLOGY AND PATHOPHYSIOLOGY OF ERECTILE DYSFUNCTION
MELMAN, A., & GINGELL, J. C. (1999) · The Journal of Urology · doi:10.1097/00005392-199901000-00004 · Cited by 254
Recovery of erectile function by the oral administration of apomorphine
Heaton, J. P. W., Morales, Á., ADAMS, M. A., Johnston, B., & El‐Rashidy, R. (1995) · Urology · doi:10.1016/0090-4295(95)80005-0 · Cited by 170
Use of nocturnal penile tumescence and rigidity in the evaluation of male erectile dysfunction.
Levine, L. A., & Lenting, E. L. (1995) · PubMed · Cited by 109
Hatzichristou, D. G., Konstantinos Hatzimouratidis, A., Ioannides, E., Yannakoyorgos, K., DIMITRIADIS, G., & Kalinderis, A. (1998) · The Journal of Urology · doi:10.1016/s0022-5347(01)63197-5 · Cited by 103
The assessment of nocturnal REM erection in the differential diagnosis of sexual impotence
Fisher, C. M., Schiavi, R. C., Lear, H., Edwards, A., Davis, D. M., & Witkin, A. P. (1975) · Journal of Sex & Marital Therapy · doi:10.1080/00926237508403702 · Cited by 100
Dula, E., Keating, W., Siami, P. F., Edmonds, A., O’Neil, J., & Buttler, S. M. (2000) · Urology · doi:10.1016/s0090-4295(00)00575-6 · Cited by 100
Self-citationOdds Ratio Inference With Dependent Data
Liang, K. (1985) · Biometrika · doi:10.1093/biomet/72.3.678 · Cited by 79
Mulhall, J. P., Bukofzer, S., Edmonds, A., & George, M. (2001) · Clinical Therapeutics · doi:10.1016/s0149-2918(01)80105-3 · Cited by 40
Self-citationA COMPARISON OF PATIENT AND PARTNER RESPONSES TO A BRIEF SEXUAL FUNCTION QUESTIONNAIRE
Mathias, S. D., O’Leary, M. P., Henning, J. M., Pasta, D. J., Fromm, S., & Rosen, R. C. (1999) · The Journal of Urology · doi:10.1016/s0022-5347(05)68086-x · Cited by 29
[The Rigiscan system in the diagnosis of male sexual impotence].
Cilurzo, P., Canale, D., Turchi, P., Giorgi, P. M., & Fabris, G. F. M. (1992) · PubMed · Cited by 18
Cited by
Morgan, P., Van Der Graaf, P. H., Arrowsmith, J., Feltner, D. E., Drummond, K. S., Wegner, C. D., & Street, S. D. A. (2012) · Drug Discovery Today · doi:10.1016/j.drudis.2011.12.020 · Cited by 692
Erectile dysfunction and its pharmacology: An overview
Patnaik, S. K., Polimati, H., & Pragada, R. R. (2017) · Asian Journal of Pharmaceutical and Clinical Research · doi:10.22159/ajpcr.2017.v10i2.15183 · Cited by 3
Metadata
- Authors
- Dula, E., Bukofzer, S., Perdok, R., & George, M.
- Affiliations
- Abbott (United States) (US)
- Takeda (United Kingdom) (GB)
- ORCID
- Bukofzer, Stan
- Venue
- European Urology
- Publisher
- Elsevier BV
- Published
- 2001
- Volume
- 39
- Issue
- 5
- Pages
- 558-564
- ISSN
- 0302-2838 (ISSN-L)
- 1421-993X
- OpenAlex
- W2036887714
- Cited by
- 131
- References
- 12
- Citations by year
- 2025: 1 · 2022: 1 · 2020: 1 · 2019: 1 · 2018: 1 · 2017: 2 · 2016: 1 · 2015: 1 · 2014: 1 · 2013: 2 · 2012: 4
- FWCI
- 14.73
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- European Urology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Sexual function and dysfunction studies
- Health Sciences › Medicine › Urology › Urological Disorders and Treatments
- Health Sciences › Medicine › Urology › Urinary Bladder and Prostate Research
- Keywords
- apomorphine, erectile dysfunction, sublingual administration, dose comparison, placebo comparison, nausea, adverse events, risk-benefit ratio
- MeSH terms
- Administration, Sublingual, Adult, Aged, Apomorphine, Coitus, Double-Blind Method, Humans, Erectile Dysfunction, Male, Middle Aged, Dopamine Agonists, Cross-Over Studies
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
