Chromosome rearrangements between chicken and guinea fowl defined by comparative chromosome painting and FISH mapping of DNA clones
Abstract
Chromosome homology between chicken (Gallus gallus) and guinea fowl (Numida meleagris) was investigated by comparative chromosome painting with chicken whole chromosome paints for chromosomes 1-9 and Z and by comparative mapping of 38 macrochromosome-specific (chromosomes 1-8 and Z) and 30 microchromosome-specific chicken cosmid DNA clones. The comparative chromosome analysis revealed that the homology of macrochromosomes is highly conserved between the two species except for two inter-chromosomal rearrangements. Guinea fowl chromosome 4 represented the centric fusion of chicken chromosome 9 with the q arm of chicken chromosome 4. Guinea fowl chromosome 5 resulted from the fusion of chicken chromosomes 6 and 7. A pericentric inversion was found in guinea fowl chromosome 7, which corresponded to chicken chromosome 8. All the chicken microchromosome-specific DNA clones were also localized to microchromosomes of guinea fowl except for several clones localized to the short arm of chromosome 4. These results suggest that the cytogenetic genome organization is highly conserved between chicken and guinea fowl.
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The synteny results were in agreement with the karyotypes for helmeted guinea fowl and chicken.
“The results were in agreement with the karyotypes for HGF and chicken (Shibusawa et al. 2002).”
From Genomic Analyses Unveil Helmeted Guinea Fowl (<i>Numida meleagris</i>) Domestication in West Africa (2021) · cites this paper as Shibusawa et al. 2002
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- Authors
- Shibusawa, M., Nishida-Umehara, C., Masabanda, J., Griffin, D. K., Isobe, T., & Matsuda, Y.
- Affiliations
- Hokkaido University (JP)
- Brunel University of London (GB)
- Venue
- Cytogenetic and Genome Research
- Publisher
- S. Karger AG
- Published
- 2002
- Volume
- 98
- Issue
- 2-3
- Pages
- 225-230
- ISSN
- 1424-859X (ISSN-L)
- 1424-8581
- OpenAlex
- W2027674592
- Cited by
- 42
- References
- 24
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 4 · 2023: 2 · 2021: 2 · 2020: 3 · 2019: 2 · 2018: 1 · 2016: 1 · 2015: 1 · 2014: 2 · 2013: 1 · 2012: 2
- FWCI
- 3.79
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Cytogenetic and Genome Research (publishedVersion)
- PubMed (publishedVersion)
- Kent Academic Repository (University of Kent) (submittedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Chromosomal and Genetic Variations
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genomic variations and chromosomal abnormalities
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genome Rearrangement Algorithms
- Keywords
- chickens, guinea fowl, comparative chromosome painting, chromosome homology, chromosomal rearrangements, Robertsonian translocation, pericentric inversion, microchromosomes, macrochromosomes, Gallus gallus
- MeSH terms
- Animals, Chickens, Chromosome Mapping, Cloning, Molecular, DNA, Karyotyping, Poultry, Gene Rearrangement, In Situ Hybridization, Fluorescence, Evolution, Molecular, Chromosome Painting, Chromosomes, Mammalian
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