Potential Action of IL-4 and IL-13 as Fibrogenic Factors on Lung Fibroblasts in vitro

Background: Asthma is characterized by chronic inflammation of the airway with the presence of Th2 cytokines. Airway remodeling in asthma is closely related to clinical manifestations. Lung myofibroblasts play a critical role in the airway remodeling and Th2 cytokines may modulate their behavior.…