Unusual double primary neoplasia: adrenocortical and ureteral carcinomas in werner syndrome
Abstract
Adrenocortical and ureteral carcinomas were observed in a 50-year-old Japanese woman with Werner syndrome (MIM No. 27770). The syndrome is an autosomal recessive disorder characterized by premature aging and an increased risk of rare cancers, which are often multiple. This is the first reported association of adrenocortical carcinoma in Werner syndrome.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
There are several reports of ACCs in patients with FAP, neurofibromatosis type 1, and Werner syndrome.
“There are several reports of ACCs in patients with familial adenomatous polyposis (FAP), neurofibromatosis type 1, and Werner syndrome (63–72).”
From Adrenocortical carcinoma (2014) · cites this paper as [63]
Cites
Positional Cloning of the Werner's Syndrome Gene
Yu, C., Oshima, J., Fu, Y., Wijsman, E. M., Hisama, F. M., Alisch, R. S., Matthews, S., Nakura, J., Miki, T., Ouais, S. G., et al. (1996) · Science · doi:10.1126/science.272.5259.258 · Cited by 1,705 · see citing works
Heterozygous Germ Line hCHK2 Mutations in Li-Fraumeni Syndrome
Bell, D. W., Varley, J. M., Szydlo, T. E., Kang, D. H., Wahrer, D. C. R., Shannon, K. E., Lubratovich, M. L., Verselis, S. J., Isselbacher, K. J., Fraumeni, J. F., et al. (1999) · Science · doi:10.1126/science.286.5449.2528 · Cited by 899 · see citing works
Excess of rare cancers in Werner syndrome (adult progeria).
Goto, M., Miller, R. W., Ishikawa, Y., & Sugano, H. (1996) · PubMed · Cited by 434 · see citing works
Self-citationLi-Fraumeni syndrome – a molecular and clinical review
Varley, J. M., Evans, D. G., & Birch, J. M. (1997) · British Journal of Cancer · doi:10.1038/bjc.1997.328 · Cited by 357 · see citing works
Genetic linkage of Werner's syndrome to five markers on chromosome 8
Goto, M., Rubenstein, M., Weber, J. L., Woods, K., & Drayna, D. T. (1992) · Nature · doi:10.1038/355735a0 · Cited by 196 · see citing works
Self-citationImmunological diagnosis of Werner syndrome by down-regulated and truncated gene products
Goto, M., Yamabe, Y., Shiratori, M., Okada, M., Kawabe, T., Matsumoto, T., Sugimoto, M., & Furuichi, Y. (1999) · Human Genetics · doi:10.1007/s004399900151 · Cited by 48 · see citing works
Self-citationGoto, M. (2001) · Gann monograph on cancer research · Cited by 18 · see citing works
Self-citationMatsumoto, T., Tsuchihashi, Z., ITO, C., et al. (1998) · Rejuvenation Research · doi:10.1089/rej.1.1998.1.131 · Cited by 13 · see citing works
Cancers of the Renal Pelvis and Ureter
Garnick, M. B., & Richie, J. P. (1983) · Springer eBooks · doi:10.1007/978-1-4684-1182-9_10 · Cited by 1 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Else, T., Kim, A. C., Sabolch, A., Raymond, V. M., Kandathil, A., Caoili, E. M., Jolly, S., Miller, B. S., Giordano, T. J., & Hammer, G. D. (2014) · Endocrine Reviews · doi:10.1210/er.2013-1029 · Cited by 892 · see citing works
- Authors
- Takazawa, R., Ajima, J., Yamauchi, A., & Goto, M.
- Affiliations
- Tokyo Metropolitan Ohtsuka Hospital (JP)
- Venue
- Urologia Internationalis
- Publisher
- S. Karger AG
- Published
- 2004
- Volume
- 72
- Issue
- 2
- Pages
- 168-170
- ISSN
- 0042-1138 (ISSN-L)
- 1423-0399
- OpenAlex
- W1988236154
- Cited by
- 11
- References
- 9
- Citations by year
- 2026: 1 · 2022: 1 · 2020: 1 · 2017: 1 · 2015: 1 · 2013: 3
- FWCI
- 0.24
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Urologia Internationalis (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Multiple and Secondary Primary Cancers
- Health Sciences › Medicine › Surgery › Adrenal and Paraganglionic Tumors
- Health Sciences › Medicine › Surgery › Urinary and Genital Oncology Studies
- Keywords
- Werner syndrome, adrenocortical carcinoma, ureteral cancer, multiple primary neoplasms, premature aging, autosomal recessive disorder, cancer risk
- MeSH terms
- Adrenal Gland Neoplasms, Carcinoma, Transitional Cell, Female, Humans, Middle Aged, Neoplasms, Multiple Primary, Tomography, X-Ray Computed, Ureteral Neoplasms, Fatal Outcome, Adrenocortical Carcinoma
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
