Etiology and Management of Seborrheic Dermatitis
Abstract
Seborrheic dermatitis (SD) is a common dermatological disorder that varies greatly in severity between individuals and with time. The etiology of this disease is poorly understood. Early investigators focused on the role of Malassezia (previously Pityrosporum) yeasts in the development of SD. Some researchers have hypothesized that there is an immunological component to SD and that this disease is caused by an altered immune response to Malassezia yeasts. However, other researchers view this condition as the result of hyperproliferation. Both antifungal and anti-inflammatory preparations have been used to treat SD effectively and safely. The wide range of antifungal formulations available (creams, shampoos, oral drugs) provides safe, effective and flexible treatment options for SD.
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SD may be associated with sex hormones such as androgens.
“Men are affected more frequently than women (3.0% vs. 2.6%) in all age groups, suggesting that SD may be associated with sex hormones such as androgens [1,3,8].”
From Seborrheic Dermatitis and Dandruff: A Comprehensive Review (2015) · cites this paper as [1]
Men are affected more frequently than women (3.0% vs. 2.6%) in all age groups.
“Men are affected more frequently than women (3.0% vs. 2.6%) in all age groups, suggesting that SD may be associated with sex hormones such as androgens [1,3,8].”
From Seborrheic Dermatitis and Dandruff: A Comprehensive Review (2015) · cites this paper as [1]
SD incidence peaks during three age periods: the first three months of life, puberty, and adulthood with an apex at 40 to 60 years of age.
“Its incidence peaks during three age periods - in the first three months of life, during puberty, and in adulthood with an apex at 40 to 60 years of age [1–4].”
From Seborrheic Dermatitis and Dandruff: A Comprehensive Review (2015) · cites this paper as [1]
Cites
Faergemann, J., Bergbrant, I.-M., Dohsé, M., Scott, A., & Westgate, G. (2001) · British Journal of Dermatology · doi:10.1046/j.1365-2133.2001.04082.x · Cited by 173 · see citing works
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Seborrheic Dermatitis and Dandruff: A Comprehensive Review
(2015) · Journal of Clinical and Investigative Dermatology · doi:10.13188/2373-1044.1000019 · Cited by 398 · see citing works
- Authors
- Gupta, A. K., Madzia, S. E., & Batra, R.
- Affiliations
- Sunnybrook Health Science Centre (CA)
- Mediprobe Research (Canada) (CA)
- ORCID
- Gupta, Aditya K.
- Venue
- Dermatology
- Publisher
- S. Karger AG
- Published
- 2004
- Volume
- 208
- Issue
- 2
- Pages
- 89-93
- ISSN
- 1018-8665 (ISSN-L)
- 1421-9832
- OpenAlex
- W2011346383
- Cited by
- 138
- References
- 1
- Citations by year
- 2026: 2 · 2025: 4 · 2024: 10 · 2023: 13 · 2022: 6 · 2021: 4 · 2020: 8 · 2019: 6 · 2018: 3 · 2017: 3 · 2016: 4 · 2015: 6 · 2014: 7 · 2013: 9 · 2012: 5
- FWCI
- 5.03
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Dermatology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Nail Diseases and Treatments
- Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
- Health Sciences › Medicine › Urology › Hair Growth and Disorders
- Keywords
- seborrheic dermatitis, Malassezia, etiology, immune response, hyperproliferation, antifungal therapy, anti-inflammatory therapy, shampoo, topical cream
- MeSH terms
- Adolescent, Adult, Anti-Infective Agents, Antifungal Agents, Child, Dermatologic Agents, Drug Therapy, Combination, Female, Humans, Male, Middle Aged, Prognosis, Dermatitis, Seborrheic, Severity of Illness Index, Treatment Outcome, Risk Assessment
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