The DOI matches its Crossref record; 37 of the 37 references it cites were found in a registry or an index.
Imprinted Genes, Placental Development and Fetal Growth
Abstract
In mammals, imprinted genes have an important role in feto-placental development. They affect the growth, morphology and nutrient transfer capacity of the placenta and, thereby, control the nutrient supply for fetal growth. In particular, the reciprocally imprinted Igf2–H19 gene complex has a central role in these processes and matches the placental nutrient supply to the fetal nutrient demands for growth. Comparison of Igf2P0 and complete Igf2 null mice has shown that interplay between placental and fetal Igf2 regulates both placental growth and nutrient transporter abundance. In turn, epigenetic modification of imprinted genes via changes in DNA methylation may provide a mechanism linking environmental cues to placental phenotype, with consequences for development both before and after birth. Changes in expression of imprinted genes, therefore, have major implications for developmental programming and may explain the poor prognosis of the infant born small for gestational age and the wide spectrum of adult-onset diseases that originate in utero.
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Cites
Genomic imprinting: parental influence on the genome
Reik, W., & Walter, J. (2001) · Nature Reviews Genetics · doi:10.1038/35047554 · Cited by 2,285
Self-citationDevelopmental Origins of the Metabolic Syndrome: Prediction, Plasticity, and Programming
Mcmillen, I. C., & Robinson, J. S. (2005) · Physiological Reviews · doi:10.1152/physrev.00053.2003 · Cited by 1,910
Lillycrop, K. A., Phillips, E. S., Jackson, A. A., Hanson, M. A., & Burdge, G. C. (2005) · The Journal of Nutrition · doi:10.1093/jn/135.6.1382 · Cited by 1,136
Placental-specific IGF-II is a major modulator of placental and fetal growth
Constância, M., Hemberger, M., Hughes, J., Dean, W., Ferguson-Smith, A., Fundele, R., Stewart, F., Kelsey, G., Fowden, A., Sibley, C., et al. (2002) · Nature · doi:10.1038/nature00819 · Cited by 1,054
Self-citationDifferential Effects of Culture on Imprinted H19 Expression in the Preimplantation Mouse Embryo1
Doherty, A. S., Mann, M. R. W., Tremblay, K. D., Bartolomei, M. S., & Schultz, R. M. (2000) · Biology of Reproduction · doi:10.1095/biolreprod62.6.1526 · Cited by 722
Waterland, R. A., & Jirtle, R. L. (2004) · Nutrition · doi:10.1016/j.nut.2003.09.011 · Cited by 613
Khosla, S., Dean, W., Brown, D., Reik, W., & Feil, R. (2001) · Biology of Reproduction · doi:10.1095/biolreprod64.3.918 · Cited by 559
Self-citationFowden, A. L., Li, J., & Forhead, A. J. (1998) · Proceedings of the Nutrition Society · doi:10.1079/pns19980017 · Cited by 484
Self-citationEndocrine mechanisms of intrauterine programming
Fowden, A. L., & Forhead, A. J. (2004) · Reproduction · doi:10.1530/rep.1.00033 · Cited by 471
Self-citationRegulation of supply and demand for maternal nutrients in mammals by imprinted genes
Reik, W., Constancia, M., Fowden, A., Anderson, N., Dean, W., Ferguson-Smith, A., Tycko, B., & Sibley, C. (2003) · The Journal of Physiology · doi:10.1111/j.1469-7793.2003.00035.x · Cited by 412
Self-citation
Cited by
Origins and consequences of DNA damage in male germ cells
Aitken, R. J., & De Iuliis, G. N. (2007) · Reproductive BioMedicine Online · doi:10.1016/s1472-6483(10)60676-1 · Cited by 425
Thyroid hormones in fetal growth and prepartum maturation
Forhead, A. J., & Fowden, A. L. (2014) · Journal of Endocrinology · doi:10.1530/joe-14-0025 · Cited by 423
Self-citationNelissen, E. C. M., van Montfoort, A. P. A., Dumoulin, J. C. M., & Evers, J. L. H. (2011) · Human Reproduction Update · doi:10.1093/humupd/dmq052 · Cited by 384
Genomic imprinting effects on brain development and function
Wilkinson, L. S., Davies, W., & Isles, A. R. (2007) · Nature Reviews Neuroscience · doi:10.1038/nrn2235 · Cited by 375
Diet-Induced Obesity Model: Abnormal Oocytes and Persistent Growth Abnormalities in the Offspring
Jungheim, E. S., Schoeller, E. L., Marquard, K. L., Louden, E. D., Schaffer, J. E., & Moley, K. H. (2010) · Endocrinology · doi:10.1210/en.2010-0098 · Cited by 366
Metadata
- Authors
- Fowden, A. L., Sibley, C., Reik, W., & Constancia, M.
- Venue
- Hormone Research in Paediatrics
- Publisher
- S. Karger AG
- Published
- 2006
- Volume
- 65
- Issue
- Suppl. 3
- Pages
- 50-58
- ISSN
- 1663-2818 (ISSN-L)
- 1663-2826
- OpenAlex
- W1965557474
- Cited by
- 274
- References
- 37
- FWCI
- 14.84
- Type
- journal article
- Language
- en
- Open access
- closed
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- Fowden, A. L., Sibley, C., Reik, W., & Constancia, M. (2006). Imprinted Genes, Placental Development and Fetal Growth. Hormone Research in Paediatrics. https://doi.org/10.1159/000091506
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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