Persistent Sexual Side Effects after SSRI Discontinuation
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New withdrawal symptoms may occur with any type of SSRI, but paroxetine is the most likely to be associated with new symptoms, while fluoxetine is the least associated.
“A bulk of literature, derived from controlled trials [18, 110, 111], case reports [19], and patients' online reports [112], showed that new withdrawal symptoms may occur with any type of SSRI, but paroxetine is the most likely to be associated with new symptoms, while fluoxetine being the least associated.”
From Acute and Persistent Withdrawal Syndromes Following Discontinuation of Psychotropic Medications (2020) · cites this paper as [110]
Cites
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Antidepressant-elicited changes in gene expression
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Self-citation
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Carvalho, A. F., Sharma, M. S., Brunoni, A. R., Vieta, E., & Fava, G. A. (2016) · Psychotherapy and Psychosomatics · doi:10.1159/000447034 · Cited by 650 · see citing works
Davies, J., & Read, J. (2019) · Addictive Behaviors · doi:10.1016/j.addbeh.2018.08.027 · Cited by 387 · see citing works
Acute and Persistent Withdrawal Syndromes Following Discontinuation of Psychotropic Medications
Cosci, F., & Chouinard, G. (2020) · Psychotherapy and Psychosomatics · doi:10.1159/000506868 · Cited by 265 · see citing works
Review: problems associated with long-term treatment with selective serotonin reuptake inhibitors
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Healy, D., Le Noury, J., & Mangin, D. (2018) · International Journal of Risk & Safety in Medicine · doi:10.3233/jrs-180744 · Cited by 81 · see citing works
Bahrick, A. S. (2008) · The Open Psychology Journal · doi:10.2174/1874350100801010042 · Cited by 41 · see citing works
Citizen petition: Sexual side effects of SSRIs and SNRIs
Healy, D. (2018) · International Journal of Risk & Safety in Medicine · doi:10.3233/jrs-180745 · Cited by 32 · see citing works
Patacchini, A., & Cosci, F. (2020) · Journal of Clinical Psychopharmacology · doi:10.1097/jcp.0000000000001154 · Cited by 10 · see citing works
- Authors
- Csoka, A. B., & Shipko, S.
- Affiliations
- University of Pittsburgh (US)
- ORCID
- Csoka, Antonei B.
- Venue
- Psychotherapy and Psychosomatics
- Publisher
- S. Karger AG
- Published
- 2006
- Volume
- 75
- Issue
- 3
- Pages
- 187-188
- ISSN
- 0033-3190 (ISSN-L)
- 1423-0348
- OpenAlex
- W2049962820
- Cited by
- 92
- References
- 13
- Citations by year
- 2026: 3 · 2025: 4 · 2024: 6 · 2023: 6 · 2022: 5 · 2021: 7 · 2020: 4 · 2019: 10 · 2018: 5 · 2017: 4 · 2016: 3 · 2015: 4 · 2014: 4 · 2013: 1 · 2012: 1
- FWCI
- 4.67
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Psychotherapy and Psychosomatics (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Sexual function and dysfunction studies
- Health Sciences › Medicine › Psychiatry and Mental health › Electroconvulsive Therapy Studies
- Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
- Keywords
- selective serotonin reuptake inhibitors, SSRI discontinuation, sexual side effects, antidepressant side effects, sexual dysfunction
- MeSH terms
- Sildenafil Citrate, Cabergoline, Adult, Androgens, Anxiety, Depressive Disorder, Ergolines, Female, Fluoxetine, Humans, Sleep Initiation and Maintenance Disorders, Male, Monoamine Oxidase Inhibitors, Piperazines, Plants, Medicinal, Purines, Selegiline, Sulfones, Testosterone, Time Factors, Vasodilator Agents, Citalopram, Bupropion, Treatment Outcome, Selective Serotonin Reuptake Inhibitors, Dopamine Agonists, Dopamine Uptake Inhibitors, Sexual Dysfunctions, Psychological, Sertraline
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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