The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Small Intestinal Bacterial Overgrowth: Diagnosis and Treatment
Abstract
Small intestinal bacterial overgrowth (SIBO) is a clinical condition characterized by a malabsorption syndrome due to an increase in microorganisms within the small intestine. The main mechanisms restricting bacterial colonization in the upper gut are the gastric acid barrier, mucosal and systemic immunity and intestinal clearance. When these mechanisms fail, bacterial overgrowth develops. Diarrhea, steatorrhea, chronic abdominal pain, bloating and flatulence are common symptoms and are similar to those observed in irritable bowel syndrome. Breath tests (glucose and/or lactulose breath tests) have been proposed as a sensitive and simple tool for the diagnosis of bacterial overgrowth, being non-invasive and inexpensive compared to the gold standard represented by the culture of intestinal aspirates. Antibiotic therapy is the cornerstone of SIBO treatment. Current SIBO treatment is based on empirical courses of broad-spectrum antibiotics since few controlled studies concerning the choice and duration of antibiotic therapy are available at present.
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Citations
Cites
Small Intestinal Bacterial Overgrowth: A Framework for Understanding Irritable Bowel Syndrome
Lin, H. C. (2004) · JAMA · doi:10.1001/jama.292.7.852 · Cited by 396
Romagnuolo, J., Schiller, D., & Bailey, R. J. (2002) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2002.05664.x · Cited by 283
Cited by
Small intestinal bacterial overgrowth syndrome
Bures, J. (2010) · World Journal of Gastroenterology · doi:10.3748/wjg.v16.i24.2978 · Cited by 620
Intestinal dysbiosis and lowered serum lipopolysaccharide-binding protein in Parkinson's disease
Hasegawa, S., Goto, S., Tsuji, H., Okuno, T., Asahara, T., Nomoto, K., Shibata, A., Fujisawa, Y., Minato, T., Okamoto, A., et al. (2015) · PLOS ONE · doi:10.1371/journal.pone.0142164 · Cited by 523
Dysbiosis of gut microbiota and microbial metabolites in Parkinson's disease
Sun, M.-F., & Shen, Y.-Q. (2018) · Ageing Research Reviews · doi:10.1016/j.arr.2018.04.004 · Cited by 445
Increased Incidence of Small Intestinal Bacterial Overgrowth During Proton Pump Inhibitor Therapy
Lombardo, L., Foti, M., Ruggia, O., & Chiecchio, A. (2010) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2009.12.022 · Cited by 350
The role of small intestinal bacterial overgrowth in Parkinson's disease
Fasano, A., Bove, F., Gabrielli, M., Petracca, M., Zocco, M. A., Ragazzoni, E., Barbaro, F., Piano, C., Fortuna, S., Tortora, A., et al. (2013) · Movement Disorders · doi:10.1002/mds.25522 · Cited by 344
Self-citation
Metadata
- Authors
- Gasbarrini, A., Lauritano, E. C., Gabrielli, M., Scarpellini, E., Lupascu, A., Ojetti, V., & Gasbarrini, G.
- Venue
- Digestive Diseases
- Publisher
- S. Karger AG
- Published
- 2007
- Volume
- 25
- Issue
- 3
- Pages
- 237-240
- ISSN
- 0257-2753 (ISSN-L)
- 1421-9875
- OpenAlex
- W1967438011
- Cited by
- 159
- References
- 2
- FWCI
- 6.41
- Type
- journal article
- Language
- en
- Open access
- closed
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- Gasbarrini, A., Lauritano, E. C., Gabrielli, M., Scarpellini, E., Lupascu, A., Ojetti, V., & Gasbarrini, G. (2007). Small Intestinal Bacterial Overgrowth: Diagnosis and Treatment. Digestive Diseases. https://doi.org/10.1159/000103892
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