The DOI matches its Crossref record; 31 of the 32 references it cites were found in a registry or an index.
Validity of Dementia Diagnoses in the Danish Hospital Registers
Abstract
Background:The validity of dementia diagnoses in the Danish nationwide hospital registers was evaluated to determine the value of these registers in epidemiological research about dementia. Methods: Two hundred patients were randomly selected from 4,682 patients registered for the first time with a dementia diagnosis in the last 6 months of 2003. The patients’ medical journals were reviewed to evaluate if they fulfilled ICD-10 and/or DSM-IV criteria for dementia and specific dementia subtypes. The patients who were still alive in 2006 were invited to an interview. Results: One hundred and ninety-seven journals were available for review and 51 patients were interviewed. A registered diagnosis of dementia was found to be correct in 169 (85.8%) cases. Regarding dementia subtypes, the degree of agreement between the registers and the results of the validating process was low with a kappa of 0.36 (95% CI 0.24–0.48). Conclusion: The validity of dementia syndrome in the Danish hospital registers was high and allows for epidemiological studies about dementia. Alzheimer’s disease, although underregistered, also had a good validity once the diagnosis was registered. In general, other ICD-10 dementia subtypes in the registers had a low validity and are less suitable for epidemiological research.
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“One potential limitation concerns the validity of the dementia diagnoses; however, the national Danish Patient Registry includes all hospital visits, and dementia diagnoses in the Danish registries have high diagnostic validity 19 , 44 ; any unregistered events would only lead to decreased power of estimates and bias results toward the null hypothesis.”
From APOE and dementia – resequencing and genotyping in 105,597 individuals (2020) · cites this paper as [44]
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“Dementia diagnoses in the Danish registries have high diagnostic validity.24,76”
From Plasma levels of apolipoprotein E, APOE genotype, and all-cause and cause-specific mortality in 105 949 individuals from a white general population cohort (2019) · cites this paper as [76]
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The Danish National Patient Registry: a review of content, data quality, and research potential
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Metadata
- Authors
- Phung, T. K. T., Andersen, B. B., Høgh, P., Kessing, L. V., Mortensen, P. B., & Waldemar, G.
- Affiliations
- Copenhagen University Hospital (DK)
- Aarhus University Hospital (DK)
- Venue
- Dementia and Geriatric Cognitive Disorders
- Publisher
- S. Karger AG
- Published
- 2007
- Volume
- 24
- Issue
- 3
- Pages
- 220-228
- ISSN
- 1420-8008 (ISSN-L)
- 1421-9824
- OpenAlex
- W2124969446
- Cited by
- 279
- References
- 32
- Citations by year
- 2026: 15 · 2025: 22 · 2024: 20 · 2023: 14 · 2022: 24 · 2021: 27 · 2020: 25 · 2019: 20 · 2018: 18 · 2017: 16 · 2016: 20 · 2015: 9 · 2014: 11 · 2013: 7 · 2012: 7
- FWCI
- 3.82
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Dementia and Geriatric Cognitive Disorders (publishedVersion)
- PubMed (publishedVersion)
- Funders
- H. Lundbeck A/S
- Fondation pour la Recherche sur Alzheimer
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Health Sciences › Health Professions › Health Information Management › Medical Coding and Health Information
- Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Reliability and Agreement in Measurement
- Keywords
- dementia, diagnostic validity, hospital registers, ICD-10, DSM-IV, Alzheimer's disease, dementia subtypes
- MeSH terms
- Aged, Aged, 80 and over, Dementia, Denmark, Female, Humans, Interview, Psychological, Male, Medical Records, Neuropsychological Tests, Psychiatric Status Rating Scales, Registries, Reproducibility of Results
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