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Cited by 244

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Arachidonic Acid and Early Human Growth: Is there a Relation?

Koletzko, Berthold, Braun, Martin·1991·Annals of Nutrition and Metabolism
DOI 10.1159/000177636
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Abstract

Growth failure is a classical sign of essential fatty acid deficiency. We investigated whether birth weight correlates with the postnatal essential fatty acid status in a group of 29 premature infants. A significant and positive correlation between body weight and plasma triglyceride content of arachidonic acid (20:4n-6) (r = 0.47, p = 0.01) and total omega-6 long-chain polyunsaturated fatty acids (r = 0.49, p less than 0.01) was found. In contrast, there was no positive relation to linoleic acid (18:2n-6) or any omega-3 fatty acid but a significant inverse correlation to alpha-linolenic acid (18:3n-3). We propose that during early life arachidonic acid may have a growth-promoting effect which could be related to its role as an eicosanoid precursor or to its structural function in membrane lipids.

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Metadata

Authors
Koletzko, B., & Braun, M.
Venue
Annals of Nutrition and Metabolism
Publisher
S. Karger AG
Published
1991
Volume
35
Issue
3
Pages
128-131
ISSN
  • 0250-6807 (ISSN-L)
  • 1421-9697
DOI
10.1159/000177636
OpenAlex
W2048061382
Cited by
244
References
0
FWCI
6.56
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Arachidonic Acid and Early Human Growth: Is there a Relation? https://app.cochat.ai/papers/10.1159/000177636
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Koletzko, B., & Braun, M. (1991). Arachidonic Acid and Early Human Growth: Is there a Relation? Annals of Nutrition and Metabolism. https://doi.org/10.1159/000177636

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