The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.
Functioning and Disability in Bipolar Disorder: An Extensive Review
Abstract
Background: Bipolar disorder has generally been regarded as having a better functional outcome than schizophrenia. However, studies have suggested low functioning in bipolar patients even when they are in clinical remission. Our aim was to determine the degree of functioning and disability in bipolar patients. Secondly, we reviewed factors potentially associated with the low functioning of bipolar patients. Method: The authors conducted an extensive Medline and Pubmed search of the published literature from 1980 up to December 2007, using a variety of search terms to find relevant articles. Bibliographies of retrieved papers were further analysed for publications of interest. Articles that reported clinically significant findings on functioning and disability, and research reports were reviewed in detail. Results: From these articles, we determined that bipolar disorder is associated with significant impairment in work, family and social life, beyond the acute phases of the illness. The aspects that appear to increase the risk of low functioning and disability in bipolar patients are mainly subsyndromal symptoms and neurocognitive impairment, among others. Conclusions: Suitable pharmacological and psychological interventions may improve the level of functioning and reduce the disability in bipolar patients. Potential targets to be considered for intervention should be residual symptoms, comorbid conditions and neurocognitive deficits. Further research is required to better identify the factors that best predict functioning in bipolar patients.
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Cites
The Long-term Natural History of the Weekly Symptomatic Status of Bipolar I Disorder
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Validity and reliability of the Functioning Assessment Short Test (FAST) in bipolar disorder
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Self-citationThe National Depressive and Manic-depressive Association (DMDA) survey of bipolar members
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“In a recent study, subsyndromal depressive symptoms, but not subsyndromal manic or hypomanic symptoms, were associated with significant impairment [”
BackgroundPost, R. M., Denicoff, K. D., Leverich, G. S., Altshuler, L. L., Frye, M. A., Suppes, T. M., Rush, A. J., Keck, P. E., McElroy, S. L., Luckenbaugh, D. A., et al. (2003) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v64n0610 · Cited by 418
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Premorbid Social Functioning in Schizophrenia and Bipolar Disorder: Similarities and Differences
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Subclinical symptoms in mood disorders: pathophysiological and therapeutic implications
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A prospective follow-up of patients with bipolar and primary unipolar affective disorder
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Cited by
Baldessarini, R. J. (2013) · doi:10.1007/978-1-4614-3710-9 · Cited by 365
Efficacy of Functional Remediation in Bipolar Disorder: A Multicenter Randomized Controlled Study
Torrent, C., Bonnin, C. D. M., Martínez-Arán, A., Valle, J., Amann, B. L., González-Pinto, A., Crespo, J. M., Ibáñez, Á., Garcia-Portilla, M. P., Tabarés-Seisdedos, R., et al. (2013) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2012.12070971 · Cited by 330
Self-citationPalmier-Claus, J. E., Berry, K., Bucci, S., Mansell, W., & Varese, F. (2016) · British Journal of Psychiatry · doi:10.1192/bjp.bp.115.179655 · Cited by 264
Meta-analysis of Theory of Mind (ToM) impairment in bipolar disorder
Bora, E., Bartholomeusz, C., & Pantelis, C. (2016) · Psychological Medicine · doi:10.1017/s0033291715001993 · Cited by 216
Subthreshold symptoms in bipolar disorder: Impact on neurocognition, quality of life and disability
Bonnín, C. M., Sánchez-Moreno, J., Martínez-Arán, A., Solé, B., Reinares, M., Rosa, A. R., Goikolea, J. M., Benabarre, A., Ayuso-Mateos, J. L., Ferrer, M., et al. (2012) · Journal of Affective Disorders · doi:10.1016/j.jad.2011.10.012 · Cited by 190
Self-citation
Metadata
- Authors
- Sanchez-Moreno, J., Martinez-Aran, A., Tabarés-Seisdedos, R., Torrent, C., Vieta, E., & Ayuso-Mateos, J. L.
- Venue
- Psychotherapy and Psychosomatics
- Publisher
- S. Karger AG
- Published
- 2009
- Volume
- 78
- Issue
- 5
- Pages
- 285-297
- ISSN
- 0033-3190 (ISSN-L)
- 1423-0348
- OpenAlex
- W2042013222
- Cited by
- 443
- References
- 19
- FWCI
- 15.14
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
