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Cited by 264

The DOI matches its Crossref record; 52 of the 52 references it cites were found in a registry or an index.

Relationship between childhood adversity and bipolar affective disorder: systematic review and meta-analysis

Open access
Palmier-Claus, J. E., Berry, K., Bucci, S., Mansell, W., Varese, F.·2016·British Journal of Psychiatry

Abstract

Background: The relationship between childhood adversity and bipolar affective disorder remains unclear. Aims: To understand the size and significance of this effect through a statistical synthesis of reported research. Method: Search terms relating to childhood adversity and bipolar disorder were entered into Medline, EMBASE, PsycINFO and Web of Science. Eligible studies included a sample diagnosed with bipolar disorder, a comparison sample and a quantitative measure of childhood adversity. Results: In 19 eligible studies childhood adversity was 2.63 times (95% CI 2.00–3.47) more likely to have occurred in bipolar disorder compared with non-clinical controls. The effect of emotional abuse was particularly robust (OR = 4.04, 95% CI 3.12–5.22), but rates of adversity were similar to those in psychiatric controls. Conclusions: Childhood adversity is associated with bipolar disorder, which has implications for the treatment of this clinical group. Further prospective research could clarify temporal causality and explanatory mechanisms.

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Research works printed but not linked: 1

  1. Bernstein, 1998, Childhood Trauma Questionnaire: A Retrospective Self-report: Manual

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Metadata

Authors
Palmier-Claus, J. E., Berry, K., Bucci, S., Mansell, W., & Varese, F.
Venue
British Journal of Psychiatry
Published
2016-12
Volume
209
Issue
6
Pages
454-459
ISSN
  • 0007-1250 (ISSN-L)
  • 1472-1465
OpenAlex
W2529294285
Cited by
264
References
52
FWCI
2.67
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Relationship between childhood adversity and bipolar affective disorder: systematic review and meta-analysis. https://app.cochat.ai/papers/10.1192/bjp.bp.115.179655
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Palmier-Claus, J. E., Berry, K., Bucci, S., Mansell, W., & Varese, F. (2016). Relationship between childhood adversity and bipolar affective disorder: systematic review and meta-analysis. British Journal of Psychiatry. https://doi.org/10.1192/bjp.bp.115.179655

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