The DOI matches its Crossref record; 52 of the 52 references it cites were found in a registry or an index.
Relationship between childhood adversity and bipolar affective disorder: systematic review and meta-analysis
Open accessAbstract
Background: The relationship between childhood adversity and bipolar affective disorder remains unclear. Aims: To understand the size and significance of this effect through a statistical synthesis of reported research. Method: Search terms relating to childhood adversity and bipolar disorder were entered into Medline, EMBASE, PsycINFO and Web of Science. Eligible studies included a sample diagnosed with bipolar disorder, a comparison sample and a quantitative measure of childhood adversity. Results: In 19 eligible studies childhood adversity was 2.63 times (95% CI 2.00–3.47) more likely to have occurred in bipolar disorder compared with non-clinical controls. The effect of emotional abuse was particularly robust (OR = 4.04, 95% CI 3.12–5.22), but rates of adversity were similar to those in psychiatric controls. Conclusions: Childhood adversity is associated with bipolar disorder, which has implications for the treatment of this clinical group. Further prospective research could clarify temporal causality and explanatory mechanisms.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
(2014) · Medical Entomology and Zoology · Cited by 17,633
Suicide as an outcome for mental disorders: A meta-analysis
Harris, E. C., & Barraclough, B. (1997) · British Journal of Psychiatry · doi:10.1192/bjp.170.3.205 · Cited by 2,589
Varese, F., Smeets, F., Drukker, M., Lieverse, R., Lataster, T., Viechtbauer, W., Read, J., van Os, J., & Bentall, R. P. (2012) · Schizophrenia Bulletin · doi:10.1093/schbul/sbs050 · Cited by 2,436
Self-citationTolin, D. F., & Foa, E. B. (2006) · Psychological Bulletin · doi:10.1037/0033-2909.132.6.959 · Cited by 2,197
Child sexual abuse and subsequent psychopathology: results from the National Comorbidity Survey
(2001) · American Journal of Public Health · doi:10.2105/ajph.91.5.753 · Cited by 1,198
Agid, O., Shapira, B., Zislin, J., Ritsner, M., Hanin, B., Murad, H., Troudart, T., Bloch, M., Heresco-Levy, U., & Lerer, B. (1999) · Molecular Psychiatry · doi:10.1038/sj.mp.4000473 · Cited by 568
Child abuse and mental disorders in Canada
Afifi, T. O., MacMillan, H. L., Boyle, M., Taillieu, T., Cheung, K., & Sareen, J. (2014) · Canadian Medical Association Journal · doi:10.1503/cmaj.131792 · Cited by 502
Functioning and Disability in Bipolar Disorder: An Extensive Review
Sanchez-Moreno, J., Martinez-Aran, A., Tabarés-Seisdedos, R., Torrent, C., Vieta, E., & Ayuso-Mateos, J. L. (2009) · Psychotherapy and Psychosomatics · doi:10.1159/000228249 · Cited by 443
Scott, K. M., Smith, D. R., & Ellis, P. M. (2010) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2010.71 · Cited by 381
Arnow, B. A. (2004) · PubMed · Cited by 315
Research works printed but not linked: 1
- Bernstein, 1998, Childhood Trauma Questionnaire: A Retrospective Self-report: Manual
Cited by
Malhi, G. S., Bell, E., Bassett, D., Boyce, P., Bryant, R., Hazell, P., Hopwood, M., Lyndon, B., Mulder, R., Porter, R., et al. (2021) · Australian & New Zealand Journal of Psychiatry · doi:10.1177/0004867420979353 · Cited by 614
Epidemiology and risk factors for bipolar disorder
Rowland, T. A., & Marwaha, S. (2018) · Therapeutic Advances in Psychopharmacology · doi:10.1177/2045125318769235 · Cited by 503
Childhood adversity and borderline personality disorder: a meta‐analysis
Porter, C., Palmier‐Claus, J., Branitsky, A., Mansell, W., Warwick, H., & Varese, F. (2020) · Acta Psychiatrica Scandinavica · doi:10.1111/acps.13118 · Cited by 450
Self-citationHeterogeneity in psychiatric diagnostic classification
Allsopp, K., Read, J., Corcoran, R., & Kinderman, P. (2019) · Psychiatry Research · doi:10.1016/j.psychres.2019.07.005 · Cited by 323
Olvera Alvarez, H. A., Kubzansky, L. D., Campen, M. J., & Slavich, G. M. (2018) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2018.06.002 · Cited by 133
Metadata
- Authors
- Palmier-Claus, J. E., Berry, K., Bucci, S., Mansell, W., & Varese, F.
- Venue
- British Journal of Psychiatry
- Publisher
- Royal College of Psychiatrists
- Published
- 2016-12
- Volume
- 209
- Issue
- 6
- Pages
- 454-459
- ISSN
- 0007-1250 (ISSN-L)
- 1472-1465
- OpenAlex
- W2529294285
- Cited by
- 264
- References
- 52
- FWCI
- 2.67
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Relationship between childhood adversity and bipolar affective disorder: systematic review and meta-analysis. https://app.cochat.ai/papers/10.1192/bjp.bp.115.179655
- The paper
- Palmier-Claus, J. E., Berry, K., Bucci, S., Mansell, W., & Varese, F. (2016). Relationship between childhood adversity and bipolar affective disorder: systematic review and meta-analysis. British Journal of Psychiatry. https://doi.org/10.1192/bjp.bp.115.179655
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.