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The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.

Organic Causes of Erectile Dysfunction in Men Under 40

Open access
Ludwig, Wesley, Phillips, Michael·2014·Urologia Internationalis
DOI 10.1159/000354931
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Abstract

There are a significant number of men under 40 who experience erectile dysfunction (ED). In the past, the vast majority of cases were thought to be psychogenic in nature. Studies have identified organic etiologies in 15-72% of men with ED under 40. Organic etiologies include vascular, neurogenic, Peyronie's disease (PD), medication side effects and endocrinologic sources. Vascular causes are commonly due to focal arterial occlusive disease. Young men with multiple sclerosis, epilepsy and trauma in close proximity to the spinal cord are at increased risk of ED. It is estimated that 8% of men with PD are under 40, with 21% of these individuals experiencing ED. Medications causing ED include antidepressants, NSAIDs and finasteride (Propecia), antiepileptics and neuroleptics. Hormonal sources are uncommon in the young population, however possible etiologies include Klinefelter's syndrome, congenital hypogonadotropic hypogonadism, and acquired hypogonadotropic hypogonadism. The workup of young men with ED should include a thorough history and physical examination. The significant prevalence of vascular etiologies of ED in young men should prompt consideration of nocturnal penile tumescence testing and penile Doppler ultrasound. Treatment options that may improve ED include exercise and oral PDE-5 inhibitors.

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Metadata

Authors
Ludwig, W., & Phillips, M.
Venue
Urologia Internationalis
Publisher
S. Karger AG
Published
2013-11-21
Volume
92
Issue
1
Pages
1-6
ISSN
  • 0042-1138 (ISSN-L)
  • 1423-0399
DOI
10.1159/000354931
OpenAlex
W2025002838
Cited by
2,156
References
6
FWCI
83.57
Type
journal article
Language
en
Open access
bronze
Licence

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CoChat. (2026). Citation check: Organic Causes of Erectile Dysfunction in Men Under 40. https://app.cochat.ai/papers/10.1159/000354931
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Ludwig, W., & Phillips, M. (2014). Organic Causes of Erectile Dysfunction in Men Under 40. Urologia Internationalis. https://doi.org/10.1159/000354931

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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