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Cited by 279

The DOI matches its Crossref record; 22 of the 22 references it cites were found in a registry or an index.

Hemodynamic Behavior During Hemodialysis: Effects of Dialysate Concentrations of Bicarbonate and Potassium

Open access
Silva, Bruno C., Freitas, Geraldo R.R., Silva, Vitor B., Abensur, Hugo, Luders, Claudio, Pereira, Benedito J., de Oliveira, Rodrigo B., Castro, Manuel C.M., Moysés, Rosa M.A., Elias, Rosilene M.·2014·Kidney and Blood Pressure Research
DOI 10.1159/000368459
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Abstract

Background/Aims: Ultrafiltration that occurs during hemodialysis (HD) promotes profound alterations in a relatively short period of time. The dialysate content of bicarbonate (DBic) and potassium (DK) may have impact over intradialytic hemodynamics, which goes beyond ultrafiltration, and its impact was evaluated in a prospective cohort. Methods: 30 patients under HD were submitted to hemodynamic assessment (HA) at the beginning and at the end of HD sessions, through a non-invasive method. Serum minus dialysate potassium concentration was expressed as K-Gap. Cardiac index (CI) and peripheral arterial resistance (PAR) variation (post-HD minus pre-HD) were expressed as ΔCI and ΔPAR. Dialysate content of sodium and calcium were expressed as DNa and DCa, respectively. Results: Mean DNa, DK and DBic were, respectively, 136.4 ± 1.1, 2.1 ± 0.6 and 38.2 ± 2.1 mEq/L. In 15 patients, DCa was >1.5 mmol/L and in the other 15 patients ≤ 1.5 mmol/L. The K-Gap ranged from 1.4 to 5.1 mEq/l (median 3.0 mEq/L). There was a reduction in post-HD CI and systolic blood pressure (ΔCI = -0.72l/min/m 2 and -11.3±15.1mmHg, respectively, p<0.001 for both). Conversely, PAR increased (ΔPAR = 272dyn.s/cm 5, p<0.001). Lower post-HD CI was was associated to higher DBic (p=0.0013) and lower K-Gap (p=0.026). In multivariate analysis, ΔCI was dependent on DBic and K-Gap, whereas ΔPAR was dependent on dialysate calcium during HD. Conclusion: We confirmed that Na and Ca dialysate content exerts and important role on hemodynamic during HD. In addition, our findings pointed out that higher dialysate concentrations of bicarbonate and potassium promote lower cardiac performance at the end of hemodialysis session.

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Metadata

Authors
Silva, B. C., Freitas, G. R. R., Silva, V. B., Abensur, H., Luders, C., Pereira, B. J., de Oliveira, R. B., Castro, M. C. M., Moysés, R. M. A., & Elias, R. M.
Venue
Kidney and Blood Pressure Research
Publisher
S. Karger AG
Published
2014
Volume
39
Issue
5
Pages
490-496
ISSN
  • 1420-4096 (ISSN-L)
  • 1423-0143
DOI
10.1159/000368459
OpenAlex
W1992676730
Cited by
279
References
22
FWCI
14.96
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Hemodynamic Behavior During Hemodialysis: Effects of Dialysate Concentrations of Bicarbonate and Potassium. https://app.cochat.ai/papers/10.1159/000368459
The paper
Silva, B. C., Freitas, G. R. R., Silva, V. B., Abensur, H., Luders, C., Pereira, B. J., de Oliveira, R. B., Castro, M. C. M., Moysés, R. M. A., & Elias, R. M. (2014). Hemodynamic Behavior During Hemodialysis: Effects of Dialysate Concentrations of Bicarbonate and Potassium. Kidney and Blood Pressure Research. https://doi.org/10.1159/000368459

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.