ENT manifestations of tuberculosis: An important aspect of ENT practice
Open accessAbstract
Tuberculosis involving organs other than the lungs is termed as 'extra pulmonary tuberculosis'. Tuberculosis (TB) remains a worldwide public health problem despite the fact that the causative organism was discovered more than 100 years ago. The present study was conducted to assess different manifestations of tuberculosis affecting the ear, nose and throat (ENT) in patients attending the outpatient department in a total of 520 cases of tuberculosis. One hundred and eight cases were of extra pulmonary tuberculosis. Sixty nine cases had the manifestations of TB in the ENT region. These included patients with tuberculous cervical lymphadenopathy (91.35), laryngeal TB (4.3%), tuberculous otitis media (1.4%), nasal TB (1.4%) and oral tuberculosis (1.4%). Extra pulmonary tuberculosis constitutes about 15-20% of all tuberculosis cases as per WHO survey and it is 20.6% in the present study.
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The average duration of symptoms prior to diagnosis of head and neck EPTB can range from 4 weeks to several months, with many patients presenting late due to absence of typical systemic symptoms like coughing or weight loss.
“According to studies as those by Menon et al. [13] and Sharma & Rana [15], the average duration of symptoms prior to diagnosis can range from 4 weeks to several months, with many patients presenting late due to the absence of typical systemic symptoms like coughing or weight loss.”
From Head and Neck Tuberculosis: A Rare Diagnosis and the Role of Surgical Biopsy and Histopathological Evaluation in Extrapulmonary Disease (2025) · cites this paper as Sharma & Rana [15]
The Results report neck swelling as the presenting complaint in cervical lymphadenitis and cough in 22 of 63 cases. The Conclusion describes ENT tuberculosis as a possible cause of chronic, long-standing symptoms. Neither section gives a 4-week-to-several-month interval before diagnosis or says that absence of cough or weight loss caused patients to present late. (LLM, conf=0.82)
Experimental — accuracy not yet measuredTypical lesions of oral TB are usually irregular, accompanied by painful ulcers that steadily increase in size.
“Typical lesions of oral TB are usually irregular, accompanied by painful ulcers that steadily increase in size. Commonly found in the oral region, easily traumatised surfaces may simply be mistaken for traumatic ulcers or carcinomas, as per our case [15,54].”
From Head and Neck Tuberculosis: A Rare Diagnosis and the Role of Surgical Biopsy and Histopathological Evaluation in Extrapulmonary Disease (2025) · cites this paper as [15]
There have been instances where polypoid-like changes were seen upon laryngeal examination, as per one of our laryngeal TB cases.
“There have been instances where, upon examination of the larynx, polypoid-like changes were seen, as per one of our laryngeal TB cases [15,44,45,46].”
From Head and Neck Tuberculosis: A Rare Diagnosis and the Role of Surgical Biopsy and Histopathological Evaluation in Extrapulmonary Disease (2025) · cites this paper as [15]
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Cites
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Self-citationMycobacterial cervical lymphadenitis.
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Eight Cases of Nasal Tuberculosis
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What happens when oral tuberculosis is not treated?
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Research works printed but not linked: 1
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Mocanu, A.-I., Mocanu, H., Moldovan, C., Soare, I., Niculet, E., Tatu, A. L., Vasile, C. I., Diculencu, D., Postolache, P. A., & Nechifor, A. (2022) · Infection and Drug Resistance · doi:10.2147/idr.s367885 · Cited by 18 · see citing works
Mogoantă, C. A., Osman, A., Georgescu, A.-M., Mitroi, A. M., Busuioc, C. I., Tănase, I., Cioboată, R., Liliac, I. M., Cimpeanu, O. L., & Ciolofan, M. S. (2025) · Pathogens · doi:10.3390/pathogens14050479 · Cited by 2 · see citing works
“Commonly found in the oral region, easily traumatised surfaces may simply be mistaken for traumatic ulcers or carcinomas, as per our case [15,54].”
Influential
- Authors
- Sharma, S., & Rana, A. K.
- Affiliations
- Safdarjang Hospital (IN)
- Corresponding author
- Rana, Amit Kumar
- Venue
- Pan African Medical Journal
- Publisher
- Pan African Medical Journal
- Published
- 2020
- Volume
- 36
- Pages
- 295-295
- ISSN
- 1937-8688 (ISSN-L)
- PMC
- PMC7572661
- OpenAlex
- W3066615667
- Cited by
- 17
- References
- 11
- Citations by year
- 2025: 1 · 2024: 5 · 2023: 3 · 2022: 7 · 2021: 1
- FWCI
- 2.51
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by
- Locations
- Pan African Medical Journal (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Health Sciences › Medicine › Surgery › Diagnosis and treatment of tuberculosis
- Health Sciences › Medicine › Infectious Diseases › Tuberculosis Research and Epidemiology
- Health Sciences › Medicine › Surgery › Infectious Diseases and Tuberculosis
- Keywords
- extrapulmonary tuberculosis, ear, nose and throat manifestations, laryngeal tuberculosis, tuberculous otitis media, nasal tuberculosis, oral tuberculosis, ENT practice
- MeSH terms
- Adult, Female, Humans, Male, Otorhinolaryngologic Diseases, Outpatient Clinics, Hospital, Prospective Studies, Tuberculosis, Tuberculosis, Laryngeal, Tuberculosis, Lymph Node, Tuberculosis, Oral, Young Adult
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