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Cited by 457

The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.

Vascular Protection: Superoxide Dismutase Isoforms in the Vessel Wall

Open access
Faraci, Frank M., Didion, Sean P.·2004·Arteriosclerosis, Thrombosis, and Vascular Biology

Abstract

Blood vessels express 3 isoforms of superoxide dismutase (SOD): cytosolic or copper-zinc SOD (CuZn-SOD), manganese SOD (Mn-SOD) localized in mitochondria, and an extracellular form of CuZn-SOD (EC-SOD). Because there are no selective pharmacological inhibitors of individual SOD isoforms, the functional importance of the different SODs has been difficult to define. Recent molecular approaches, primarily the use of genetically-altered mice and viral-mediated gene transfer, have allowed investigators to begin to define the role of specific SOD isoforms in vascular biology. This review will focus mainly on the role of individual SODs in relation to endothelium under normal conditions and in disease states. This area is important because reactive oxygen species and superoxide anion are thought to play major roles in changes in vascular structure and function in pathophysiology.

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Metadata

Authors
Faraci, F. M., & Didion, S. P.
Venue
Arteriosclerosis, Thrombosis, and Vascular Biology
Published
2004-08
Volume
24
Issue
8
Pages
1367-1373
ISSN
  • 1079-5642 (ISSN-L)
  • 1524-4636
OpenAlex
W2121415692
Cited by
457
References
5
FWCI
15.39
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Vascular Protection: Superoxide Dismutase Isoforms in the Vessel Wall. https://app.cochat.ai/papers/10.1161/01.atv.0000133604.20182.cf
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Faraci, F. M., & Didion, S. P. (2004). Vascular Protection: Superoxide Dismutase Isoforms in the Vessel Wall. Arteriosclerosis, Thrombosis, and Vascular Biology. https://doi.org/10.1161/01.atv.0000133604.20182.cf

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.