Cited by 298Lipoproteins and Cardiovascular HealthCholesterol and Lipid MetabolismParaoxonase enzyme and polymorphisms

The DOI matches its Crossref record; 30 of the 30 references it cites were found in a registry or an index.

High-density lipoprotein subpopulation profile and coronary heart disease prevalence in male participants of the Framingham Offspring Study.

Open access

Asztalos, Bela F., Cupples, L. Adrienne, Demissie, Serkalem, Horvath, Katalin V., Cox, Caitlin E., Batista, Marcelo C., Schaefer, Ernst J.·2004·Arteriosclerosis, Thrombosis, and Vascular Biology

DOI 10.1161/01.atv.0000146325.93749.a8

Open this paper in CoChat — free account Open PDF

Abstract

OBJECTIVE: High-density lipoprotein (HDL) is a heterogeneous lipoprotein class and there is no consensus on the value of HDL subspecies in coronary heart disease (CHD) risk assessment. We tested the hypothesis whether specific HDL subpopulations are significantly associated with CHD-prevalence. METHODS AND RESULTS: ApoA-I concentrations (mg/dL) in HDL subpopulations were quantitatively determined by native 2d gel electrophoresis, immunoblotting, and image analysis in male participants in the Framingham Offspring Study (FOS). CHD cases (n=169) had higher prebeta-1 and alpha-3 particle and lower alpha-1, prealpha-3, and prealpha-1 particle levels than either all (n=1277) or HDL cholesterol-matched (n=358) controls. alpha-1 and prealpha-3 levels had an inverse association, whereas alpha-3 and prealpha-1 particle levels had a positive association with CHD prevalence after adjusting the data for established CHD risk factors. Standardized logit coefficients indicated that alpha-1 HDL was most significantly associated with CHD prevalence. Moreover, each mg/dL increase in alpha-1 particle level decreased odds of CHD by 26% (P<0.0001), whereas each mg/dL increase in HDL cholesterol decreased odds of CHD by 2% in a model including all established CHD risk factors. CONCLUSIONS: Specific HDL subpopulations were positively correlated, whereas others were inversely correlated with CHD prevalence in male subject in the FOS, indicating that the various HDL particles might have different roles in the cause of CHD.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1161/01.atv.0000146325.93749.a8

Cites

30 of 30 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Effect of Recombinant ApoA-I Milano on Coronary Atherosclerosis in Patients With Acute Coronary Syndromes: A Randomized Controlled Trial
Nissen, S. E., Tsunoda, T., Tuzcu, E. M., Schoenhagen, P., Cooper, C. J., Yasin, M., Eaton, G. M., Lauer, M. A., Sheldon, W. S., Grines, C. L., et al. (2003) · JAMA · doi:10.1001/jama.290.17.2292 · Cited by 1,707
AN INVESTIGATION OF CORONARY HEART DISEASE IN FAMILIES
Kannel, W. B., Feinleib, M., McNAMARA, P. M., Garrison, R. J., & Castelli, W. P. (1979) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a112813 · Cited by 1,639
Molecular physiology of reverse cholesterol transport.
Fielding, C. J., & Fielding, P. E. (1995) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)39898-9 · Cited by 1,448
A prospective study of cholesterol, apolipoproteins, and the risk of myocardial infarction.
Stampfer, M. J., Sacks, F. M., Salvini, S., Willett, W. C., & Hennekens, C. H. (1991) · New England Journal of Medicine · doi:10.1056/nejm199108083250601 · Cited by 1,163
The Framingham Offspring Study
Allhoff, P., Laaser, U., & Heinrich, J. (1991) · Springer eBooks · doi:10.1007/978-3-642-95642-3_25 · Cited by 832
Early incorporation of cell-derived cholesterol into pre-.beta.-migrating high-density lipoprotein
Castro, G. R., & Fielding, C. J. (1988) · Biochemistry · doi:10.1021/bi00401a005 · Cited by 641
Autoradiography using storage phosphor technology
Johnston, R. F., Pickett, S. C., & Barker, D. L. A. (1990) · Electrophoresis · doi:10.1002/elps.1150110503 · Cited by 525
Apolipoprotein A-I containing lipoproteins in coronary artery disease
Puchois, P., Kandoussi, A., Fievet, P., Fourrier, J. L., Bertrand, M. E., Koren, E., & Fruchart, J. (1987) · Atherosclerosis · doi:10.1016/0021-9150(87)90091-8 · Cited by 326
Two-dimensional electrophoresis of plasma lipoproteins: Recognition of new apo A-I-containing subpopulations
Asztalos, B. F., Sloop, C. H., Wong, L., & Roheim, P. S. (1993) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(93)90253-6 · Cited by 235
Self-citation
A case-control study of lipoprotein particles in two populations at contrasting risk for coronary heart disease. The ECTIM Study.
Parra, H. J., Arveiler, D., Evans, A. E., Cambou, J., Amouyel, P., Bingham, A., McMaster, D., Schaffer, P., DOUSTE‐BLAZY, P., & Luc, G. (1992) · Arteriosclerosis and Thrombosis A Journal of Vascular Biology · doi:10.1161/01.atv.12.6.701 · Cited by 232

Show all 30 references

Research works printed but not linked: 7

10.1161/circ.90.2.8044946 · DOI
10.1161/circ.85.1.1728453 · DOI
10.1161/atvb.20.12.2670 · DOI
10.1161/atvb.17.10.1885 · DOI
1996, Clin Chem, 42, 12;1992
10.1161/circ.100.6.594 · DOI
10.1161/atvb.21.8.1320 · DOI

Sorted by citations

Evaluation and Treatment of Hypertriglyceridemia: An Endocrine Society Clinical Practice Guideline
Berglund, L., Brunzell, J. D., Goldberg, A. C., Goldberg, I. J., Sacks, F., Murad, M. H., & Stalenhoef, A. F. H. (2012) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2011-3213 · Cited by 887
Functionally Defective High-Density Lipoprotein: A New Therapeutic Target at the Crossroads of Dyslipidemia, Inflammation, and Atherosclerosis
Kontush, A., & Chapman, M. J. (2006) · Pharmacological Reviews · doi:10.1124/pr.58.3.1 · Cited by 647
High-Density Lipoprotein Subfractions - What the Clinicians Need to Know
Pirillo, A., Norata, G. D., & Catapano, A. L. (2013) · Cardiology · doi:10.1159/000346463 · Cited by 754
Endothelial and Antithrombotic Actions of HDL
Mineo, C., Deguchi, H., Griffin, J. H., & Shaul, P. W. (2006) · Circulation Research · doi:10.1161/01.res.0000225982.01988.93 · Cited by 663
HDL Measures, Particle Heterogeneity, Proposed Nomenclature, and Relation to Atherosclerotic Cardiovascular Events
Rosenson, R. S., Brewer, H. B., Chapman, M. J., Fazio, S., Hussain, M. M., Kontush, A., Krauss, R. M., Otvos, J. D., Remaley, A. T., & Schaefer, E. J. (2011) · Clinical Chemistry · doi:10.1373/clinchem.2010.155333 · Cited by 523
Self-citation
Biological activities of HDL subpopulations and their relevance to cardiovascular disease
Camont, L., Chapman, M. J., & Kontush, A. (2011) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2011.05.013 · Cited by 484
High-density lipoproteins: A consensus statement from the National Lipid Association
Toth, P. P., Barter, P. J., Rosenson, R. S., Boden, W. E., Chapman, M. J., Cuchel, M., D'Agostino, R. B., Davidson, M. H., Davidson, W. S., Heinecke, J. W., et al. (2013) · Journal of Clinical Lipidology · doi:10.1016/j.jacl.2013.08.001 · Cited by 336
Paradoxical association of enhanced cholesterol efflux with increased incident cardiovascular risks
Li, X.-M., Tang, W. H. W., Mosior, M. K., Huang, Y., Wu, Y., Matter, W., Gao, V., Schmitt, D., DiDonato, J. A., Fisher, E. A., et al. (2013) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/atvbaha.113.301373 · Cited by 301
Lipoprotein subfractions and cardiovascular disease risk
Krauss, R. M. (2010) · Current Opinion in Lipidology · doi:10.1097/mol.0b013e32833b7756 · Cited by 272
Value of High-Density Lipoprotein (HDL) Subpopulations in Predicting Recurrent Cardiovascular Events in the Veterans Affairs HDL Intervention Trial
Asztalos, B. F., Collins, D., Cupples, L. A., Demissie, S., Horvath, K. V., Bloomfield, H. E., Robins, S. J., & Schaefer, E. J. (2005) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/01.atv.0000183727.90611.4f · Cited by 268
Self-citation
Do trans fatty acids from industrially produced sources and from natural sources have the same effect on cardiovascular disease risk factors in healthy subjects? Results of the trans Fatty Acids Collaboration (TRANSFACT) study
Chardigny, J.-M., Destaillats, F., Malpuech-Brugère, C., Moulin, J., Bauman, D. E., Lock, A. L., Barbano, D. M., Mensink, R. P., Bezelgues, J.-B., Chaumont, P., et al. (2008) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/87.3.558 · Cited by 252
HDL particle number and size as predictors of cardiovascular disease
Kontush, A. (2015) · Frontiers in Pharmacology · doi:10.3389/fphar.2015.00218 · Cited by 222
Differential effects of HDL subpopulations on cellular ABCA1- and SR-BI-mediated cholesterol efflux
Asztalos, B. F., de la Llera-Moya, M., Dallal, G. E., Horvath, K. V., Schaefer, E. J., & Rothblat, G. H. (2005) · Journal of Lipid Research · doi:10.1194/jlr.m500187-jlr200 · Cited by 224
Self-citation
The HDL hypothesis: does high-density lipoprotein protect from atherosclerosis?
Vergeer, M., Holleboom, A. G., Kastelein, J. J. P., & Kuivenhoven, J. A. (2010) · Journal of Lipid Research · doi:10.1194/jlr.r001610 · Cited by 222
Cholesterol transport system: An integrated cholesterol transport model involved in atherosclerosis
Yu, X.-H., Zhang, D., Zheng, X., & Tang, C. (2018) · Progress in Lipid Research · doi:10.1016/j.plipres.2018.12.002 · Cited by 222
Multiple actions of high-density lipoprotein
Florentin, M., Liberopoulos, E. N., Wierzbicki, A. S., & Mikhailidis, D. P. (2008) · Current Opinion in Cardiology · doi:10.1097/hco.0b013e3283043806 · Cited by 200
Metabolic and functional relevance of HDL subspecies
Asztalos, B. F., Tani, M., & Schaefer, E. J. (2011) · Current Opinion in Lipidology · doi:10.1097/mol.0b013e3283468061 · Cited by 201
Self-citation
Small Dense Low‐Density Lipoprotein Cholesterol Is the Most Atherogenic Lipoprotein Parameter in the Prospective Framingham Offspring Study
Ikezaki, H., Lim, E., Cupples, L. A., Liu, C., Asztalos, B. F., & Schaefer, E. J. (2021) · Journal of the American Heart Association · doi:10.1161/jaha.120.019140 · Cited by 200
Self-citation
Laboratory Assessment of HDL Heterogeneity and Function
Movva, R., & Rader, D. J. (2008) · Clinical Chemistry · doi:10.1373/clinchem.2007.101923 · Cited by 190
Small Dense LDL Cholesterol and Coronary Heart Disease: Results from the Framingham Offspring Study
Ai, M., Otokozawa, S., Asztalos, B. F., Ito, Y., Nakajima, K., White, C. C., Cupples, L. A., Wilson, P. W. F., & Schaefer, E. J. (2010) · Clinical Chemistry · doi:10.1373/clinchem.2009.137489 · Cited by 183
Self-citation
Efficacy and Safety of a Novel Oral Inducer of Apolipoprotein A-I Synthesis in Statin-Treated Patients With Stable Coronary Artery Disease
Nicholls, S. J., Gordon, A., Johansson, J., Wolski, K., Ballantyne, C. M., Kastelein, J. J. P., Taylor, A. J., Borgman, M., & Nissen, S. E. (2011) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2010.11.015 · Cited by 172
Dietary Fructose and Glucose Differentially Affect Lipid and Glucose Homeostasis
Schaefer, E. J., Gleason, J. A., & Dansinger, M. L. (2009) · Journal of Nutrition · doi:10.3945/jn.108.098186 · Cited by 169
Self-citation
Apolipoprotein C‐III as a Potential Modulator of the Association Between HDL‐Cholesterol and Incident Coronary Heart Disease
Jensen, M. K., Rimm, E. B., Furtado, J. D., & Sacks, F. M. (2012) · Journal of the American Heart Association · doi:10.1161/jaha.111.000232 · Cited by 142
High-density lipoprotein subclasses and their relationship to cardiovascular disease
Superko, H. R., PENDYALA, L. K., Williams, P. T., Momary, K. M., King, S. B., & Garrett, B. C. (2012) · Journal of clinical lipidology · doi:10.1016/j.jacl.2012.03.001 · Cited by 142
Therapeutic elevation of HDL-cholesterol to prevent atherosclerosis and coronary heart disease
Chapman, M. J. (2006) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2006.02.003 · Cited by 138
Is raising HDL a futile strategy for atheroprotection?
JOY, T. R., & Hegele, R. A. (2008) · Nature Reviews Drug Discovery · doi:10.1038/nrd2489 · Cited by 139
From High-Density Lipoprotein Cholesterol to Measurements of Function
Sacks, F. M., & Jensen, M. K. (2018) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.117.307025 · Cited by 121
Templated high density lipoprotein nanoparticles as potential therapies and for molecular delivery
Damiano, M. G., Mutharasan, R. K., Tripathy, S., McMahon, K. M., & Thaxton, C. S. (2012) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2012.07.013 · Cited by 119
Comparison of effects of diet versus exercise weight loss regimens on LDL and HDL particle size in obese adults
Varady, K. A., Bhutani, S., Klempel, M. C., & Kroeger, C. M. (2011) · Lipids in Health and Disease · doi:10.1186/1476-511x-10-119 · Cited by 116
Hyperhomocysteinemia due to cystathionine beta synthase deficiency induces dysregulation of genes involved in hepatic lipid homeostasis in mice
Hamelet, J., Demuth, K., Paul, J., Delabar, J. M., & Janel, N. (2006) · Journal of Hepatology · doi:10.1016/j.jhep.2006.07.028 · Cited by 114
Effects of weight loss, induced by gastric bypass surgery, on HDL remodeling in obese women
Asztalos, B. F., Swarbrick, M. M., Schaefer, E. J., Dallal, G. E., Horvath, K. V., Ai, M., Stanhope, K. L., Austrheim-Smith, I. T., Wolfe, B. M., Ali, M., et al. (2010) · Journal of Lipid Research · doi:10.1194/jlr.p900015 · Cited by 108
Self-citation
Novel metabolic biomarkers of cardiovascular disease
Jensen, M. K., Bertoia, M. L., Cahill, L. E., Agarwal, I., Rimm, E. B., & Mukamal, K. J. (2014) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2014.155 · Cited by 109
Selective effect of conjugated linoleic acid isomers on atherosclerotic lesion development in apolipoprotein E knockout mice
Arbonés-Mainar, J. M., Navarro, M. Á., Guzmán, M., Arnal, C., Surra, J. C., Acı́n, S., Carnicer, R., Osada, J., & Roche, H. M. (2006) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2006.01.015 · Cited by 102
Effects of weight loss, induced by gastric bypass surgery, on HDL remodeling in obese women
Asztalos, B. F., Swarbrick, M. M., Schaefer, E. J., Dallal, G. E., Horvath, K. V., Ai, M., Stanhope, K. L., Austrheim-Smith, I. T., Wolfe, B. M., Ali, M. R., et al. (2009) · Journal of Lipid Research · doi:10.1194/jlr.p900015-jlr200 · Cited by 102
Self-citation
Cholesterol efflux capacity, macrophage reverse cholesterol transport and cardioprotective HDL
Hutchins, P. M., & Heinecke, J. W. (2015) · Current Opinion in Lipidology · doi:10.1097/mol.0000000000000209 · Cited by 97
Adiponectin: An independent risk factor for coronary heart disease in men in the Framingham offspring Study
Ai, M., Otokozawa, S., Asztalos, B. F., White, C. C., Cupples, L. A., Nakajima, K., Lamon‐Fava, S., Wilson, P. W. F., Matsuzawa, Y., & Schaefer, E. J. (2011) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2011.05.035 · Cited by 91
Self-citation
Structural Analysis of Nanoscale Self-Assembled Discoidal Lipid Bilayers by Solid-State NMR Spectroscopy
Li, Y., Kijac, A. Z., Sligar, S. G., & Rienstra, C. M. (2006) · Biophysical Journal · doi:10.1529/biophysj.106.087072 · Cited by 87
Subfractions and Subpopulations of HDL: An Update
Rizzo, M., Otvos, J. D., Nikolić, D., Montalto, G., Toth, P. P., & Banach, M. (2014) · Current Medicinal Chemistry · doi:10.2174/0929867321666140414103455 · Cited by 84
Comparison of the Effects of High Doses of Rosuvastatin Versus Atorvastatin on the Subpopulations of High-Density Lipoproteins
Asztalos, B. F., Maulf, F. L., Dallal, G. E., Stein, E. A., Jones, P. H., Horvath, K. V., McTaggart, F., & Schaefer, E. J. (2007) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2006.09.117 · Cited by 84
Self-citation
Apolipoprotein structural organization in high density lipoproteins: belts, bundles, hinges and hairpins
Davidson, W. S., & Silva, R. G. D. (2005) · Current Opinion in Lipidology · doi:10.1097/01.mol.0000169349.38321.ad · Cited by 80
Protease inhibitor-based HAART, HDL, and CHD-risk in HIV-infected patients
Asztalos, B. F., Schaefer, E. J., Horvath, K. V., Cox, C. E., Skinner, S. C., Gerrior, J., Gorbach, S. L., & WANKE, C. A. (2005) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2005.04.013 · Cited by 80
Self-citation
High-density lipoprotein: Is it always atheroprotective?
Ansell, B. J., Fonarow, G. C., & Fogelman, A. M. (2006) · Current Atherosclerosis Reports · doi:10.1007/s11883-006-0038-4 · Cited by 80
Alterations in the High Density Lipoprotein Phenotype and HDL‐Associated Enzymes in Subjects with Metabolic Syndrome
Lagos, K. G., Filippatos, T. D., Tsimihodimos, V., Gazi, I. F., Rizos, C. V., Tselepis, A. D., Mikhailidis, D. P., & Elisaf, M. (2008) · Lipids · doi:10.1007/s11745-008-3251-9 · Cited by 74
Relation of gemfibrozil treatment and high-density lipoprotein subpopulation profile with cardiovascular events in the Veterans Affairs High-Density Lipoprotein Intervention Trial.
Asztalos, B. F., Collins, D., Horvath, K. V., Bloomfield, H. E., Robins, S. J., & Schaefer, E. J. (2008) · Metabolism · doi:10.1016/j.metabol.2007.08.009 · Cited by 71
Self-citation
Tailoring of Biomimetic High-Density Lipoprotein Nanostructures Changes Cholesterol Binding and Efflux
Luthi, A. J., Zhang, H., Kim, D., Giljohann, D. A., Mirkin, C. A., & Thaxton, C. S. (2011) · ACS Nano · doi:10.1021/nn2035457 · Cited by 73
Genetic and secondary causes of severe HDL deficiency and cardiovascular disease
Geller, A. S., Polisecki, E. Y., Diffenderfer, M. R., Asztalos, B. F., Karathanasis, S. K., Hegele, R. A., & Schaefer, E. J. (2018) · Journal of Lipid Research · doi:10.1194/jlr.m088203 · Cited by 74
Self-citation
Increase HDL-C level over the menopausal transition is associated with greater atherosclerotic progression
Khoudary, S. R. E., Wang, L., Brooks, M. M., Thurston, R. C., Derby, C. A., & Matthews, K. A. (2016) · Journal of clinical lipidology · doi:10.1016/j.jacl.2016.04.008 · Cited by 74
Relation of Increased Prebeta-1 High-Density Lipoprotein Levels to Risk of Coronary Heart Disease
Guey, L. T., Pullinger, C. R., Ishida, B. Y., O'Connor, P. M., Zellner, C., Francone, O. L., Laramie, J. M., Naya-Vigne, J. M., Siradze, K. A., Deedwania, P., et al. (2011) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2011.03.054 · Cited by 70
The complexity of HDL
Francis, G. A. (2010) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2010.08.009 · Cited by 69
High-Density Lipoprotein Particle Subclass Heterogeneity and Incident Coronary Heart Disease
Akinkuolie, A. O., Paynter, N. P., Padmanabhan, L., & Mora, S. (2013) · Circulation Cardiovascular Quality and Outcomes · doi:10.1161/circoutcomes.113.000675 · Cited by 69
Biogenesis and speciation of nascent apoA-I-containing particles in various cell lines
Krimbou, L., Hassan, H. H., Blain, S., Rashid, S., Denis, M., Marcil, M., & Genest, J. J. (2005) · Journal of Lipid Research · doi:10.1194/jlr.m500038-jlr200 · Cited by 69
Plasma Levels of HDL Subpopulations and Remnant Lipoproteins Predict the Extent of Angiographically-Defined Coronary Artery Disease in Postmenopausal Women
Lamon‐Fava, S., Herrington, D. M., Reboussin, D. M., Sherman, M., Horvath, K. V., Cupples, L. A., White, C. C., Demissie, S., Schaefer, E. J., & Asztalos, B. F. (2008) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.107.157123 · Cited by 67
Self-citation
HDL and atherosclerosis: Insights from inherited HDL disorders
Calabresi, L., Gomaraschi, M., Simonelli, S., Bernini, F., & Franceschini, G. (2014) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2014.07.015 · Cited by 67
LDL and HDL subclasses and their relationship with Framingham risk score in middle-aged Serbian population
Vekić, J., Topić, A., Zeljković, A., Jelić‐Ivanović, Z., & Spasojević‐Kalimanovska, V. (2007) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2006.11.013 · Cited by 66
Characterization of high density lipoprotein particles in familial apolipoprotein A-I deficiency
Santos, R. D., Schaefer, E. J., Asztalos, B. F., Polisecki, E. Y., Wang, J., Hegele, R. A., Martinez, L. R. C., Miname, M. H., Rochitte, C. E., da Luz, P. L., et al. (2007) · Journal of Lipid Research · doi:10.1194/jlr.m700362-jlr200 · Cited by 65
Self-citation
Relationship between total cholesterol/high-density lipoprotein cholesterol ratio, triglyceride/high-density lipoprotein cholesterol ratio, and high-density lipoprotein subclasses
Jia, L., Long, S., Fu, M., Yan, B., Tian, Y., Xu, Y., & Gou, L. (2006) · Metabolism · doi:10.1016/j.metabol.2006.04.004 · Cited by 64
Genetic variants associated with fasting blood lipids in the U.S. population: Third National Health and Nutrition Examination Survey
Chang, M., Yesupriya, A., Ned, R. M., Mueller, P. W., & Dowling, N. F. (2010) · BMC Medical Genetics · doi:10.1186/1471-2350-11-62 · Cited by 65
ABCA1, ABCG1, and Cholesterol Homeostasis
Yu, X.-H., & Tang, C. (2022) · Advances in experimental medicine and biology · doi:10.1007/978-981-19-1592-5_7 · Cited by 72
Identification of Fibrin Clot-Bound Plasma Proteins
Talens, S., Leebeek, F. W. G., Demmers, J., & Rijken, D. C. (2012) · PLoS ONE · doi:10.1371/journal.pone.0041966 · Cited by 64
Cholesterol is Inefficiently Converted to Cholesteryl Esters in the Blood of Cardiovascular Disease Patients
Gerl, M. J., Vaz, W. L. C., Domingues, N. S., Klose, C. D., Surma, M. A., Sampaio, J. L., Almeida, M. S., Rodrigues, G., Gonçalves, P. D. A., Ferreira, J., et al. (2018) · Scientific Reports · doi:10.1038/s41598-018-33116-4 · Cited by 66
HDL and the menopause
Khoudary, S. R. E. (2017) · Current Opinion in Lipidology · doi:10.1097/mol.0000000000000432 · Cited by 66
Novel Apo E-Derived ABCA1 Agonist Peptide (CS-6253) Promotes Reverse Cholesterol Transport and Induces Formation of preβ-1 HDL In Vitro
Hafiane, A., Bielicki, J. K., Johansson, J. O., & Genest, J. (2015) · PLOS ONE · doi:10.1371/journal.pone.0131997 · Cited by 57
Prebeta-1 HDL and coronary heart disease
Kane, J. P., & Malloy, M. J. (2012) · Current Opinion in Lipidology · doi:10.1097/mol.0b013e328353eef1 · Cited by 61
HDL-apoA-I Exchange: Rapid Detection and Association with Atherosclerosis
Borja, M. S., Zhao, L., Hammerson, B., Tang, C., Yang, R., Carson, N., Fernando, G., Liu, X., Budamagunta, M. S., Genest, J. J., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0071541 · Cited by 62
Effects of Maximal Doses of Atorvastatin Versus Rosuvastatin on Small Dense Low-Density Lipoprotein Cholesterol Levels
Ai, M., Otokozawa, S., Asztalos, B. F., Nakajima, K., Stein, E. A., Jones, P. H., & Schaefer, E. J. (2007) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2007.08.035 · Cited by 60
Self-citation
New insights into the biogenesis of human high-density lipoproteins
Krimbou, L., Marcil, M., & Genest, J. J. (2006) · Current Opinion in Lipidology · doi:10.1097/01.mol.0000226117.43178.7c · Cited by 57
Abnormal HDL subclasses distribution in overweight children with insulin resistance or type 2 diabetes mellitus
Pérez-Méndez, O. A., Torres‐Tamayo, M., Posadas‐Romero, C., Garcés, V. V., Carreón‐Torres, E., Mendoza-Peŕez, E., Urrutia, A. X. M., Huesca‐Gómez, C., Zamora‐González, J., & Aguilar-Herrera, B. E. (2006) · Clinica Chimica Acta · doi:10.1016/j.cca.2006.07.003 · Cited by 56
Association of oxidative stress and PON1 with LDL and HDL particle size in middle‐aged subjects
Vekić, J., Kotur‐Stevuljevic, J., Jelić‐Ivanović, Z., Spasić, S., Spasojević‐Kalimanovska, V., Topić, A., Zeljković, A., Stefanović, A., & Zunic, G. (2007) · European Journal of Clinical Investigation · doi:10.1111/j.1365-2362.2007.01849.x · Cited by 55
Mast cells promote atherosclerosis by inducing both an atherogenic lipid profile and vascular inflammation
Heikkilä, H. M., Trosien, J., Metso, J., Jauhiainen, M., Pentikäinen, M. O., Kovanen, P. T., & Lindstedt, K. A. (2009) · Journal of Cellular Biochemistry · doi:10.1002/jcb.22443 · Cited by 53
The relationship between high density lipoprotein subclass profile and plasma lipids concentrations
Tian, L., & Fu, M. (2010) · Lipids in Health and Disease · doi:10.1186/1476-511x-9-118 · Cited by 53
Time to ditch HDL-C as a measure of HDL function?
Ronsein, G. E., & Heinecke, J. W. (2017) · Current Opinion in Lipidology · doi:10.1097/mol.0000000000000446 · Cited by 51
High-Density Lipoprotein Particles, Cell-Cholesterol Efflux, and Coronary Heart Disease Risk
Asztalos, B. F., Horvath, K. V., & Schaefer, E. J. (2018) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.118.311117 · Cited by 50
Self-citation
Cholesteryl ester transfer protein inhibition, high-density lipoprotein metabolism and heart disease risk reduction
Schaefer, E. J., & Asztalos, B. F. (2006) · Current Opinion in Lipidology · doi:10.1097/01.mol.0000236364.63840.d8 · Cited by 49
Self-citation
Lipid and lipoprotein profiles and prevalence of dyslipidemia in Mexican adolescents
Posadas‐Sánchez, R., Posadas‐Romero, C., Zamora‐González, J., Mendoza-Peŕez, E., Cardoso-Saldaña, G. C., & Yamamoto-Kimura, L. T. (2007) · Metabolism · doi:10.1016/j.metabol.2007.07.009 · Cited by 48
Niacin: another look at an underutilized lipid-lowering medication
Creider, J. C., Hegele, R. A., & JOY, T. R. (2012) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2012.22 · Cited by 49
The effects of statins on high-density lipoproteins
Schaefer, E. J., & Asztalos, B. F. (2006) · Current Atherosclerosis Reports · doi:10.1007/s11883-006-0063-3 · Cited by 47
Self-citation
A moderate-fat diet containing pistachios improves emerging markers of cardiometabolic syndrome in healthy adults with elevated LDL levels
Holligan, S. D., West, S. G., Gebauer, S. K., Kay, C. D., & Kris‐Etherton, P. M. (2014) · British Journal Of Nutrition · doi:10.1017/s0007114514001561 · Cited by 46
Regulation of inflammatory and lipid metabolism genes by eicosapentaenoic acid-rich oil
Gillies, P. J., Bhatia, S. K., Belcher, L. A., Hannon, D. B., Thompson, J. T., & Heuvel, J. P. V. (2012) · Journal of Lipid Research · doi:10.1194/jlr.m022657 · Cited by 45
Glucoregulatory and Cardiometabolic Profiles of Almond vs. Cracker Snacking for 8 Weeks in Young Adults: A Randomized Controlled Trial
Dhillon, J., Thorwald, M. A., Cruz, N. D. L., Vu, E., Asghar, S. A., Kuse, Q., Rios, L. K. D., & Ortiz, R. M. (2018) · Nutrients · doi:10.3390/nu10080960 · Cited by 45
The lipoprotein subfraction profile: heritability and identification of quantitative trait loci
Kaess, B. M., Fischer, M., Baessler, A., Stark, K. J., Huber, F., Kremer, W., Kalbitzer, H. R., Schunkert, H., Riegger, G. A. J., & Hengstenberg, C. (2007) · Journal of Lipid Research · doi:10.1194/jlr.m700338-jlr200 · Cited by 44
HDL‐3 is a Superior Predictor of Carotid Artery Disease in a Case‐Control Cohort of 1725 Participants
Kim, D. S., Burt, A., Rosenthal, E. A., Ranchalis, J., Eintracht, J. F., Hatsukami, T. S., Furlong, C. E., Marcovina, S. M., Albers, J. J., & Jarvik, G. P. (2014) · Journal of the American Heart Association · doi:10.1161/jaha.114.000902 · Cited by 45
Composition-function analysis of HDL subpopulations: influence of lipid composition on particle functionality
Niisuke, K., Kuklenyik, Z., Horvath, K. V., Gardner, M. S., Toth, C. A., & Asztalos, B. F. (2020) · Journal of Lipid Research · doi:10.1194/jlr.ra119000258 · Cited by 45
Self-citation
High-density lipoprotein subclasses are a potential intermediary between alcohol intake and reduced risk of cardiovascular disease: The Rancho Bernardo Study
Muth, N. D., Laughlin, G. A., von Mühlen, D. G., Smith, S. C., & Barrett-Connor, E. L. (2010) · British Journal Of Nutrition · doi:10.1017/s0007114510001595 · Cited by 42
The effect of chronic kidney disease on lipid metabolism
Di̇nçer, N., Dağel, T., Afşar, B., Covic, A. C., Ortíz, A., & Kanbay, M. (2018) · International Urology and Nephrology · doi:10.1007/s11255-018-2047-y · Cited by 42
LpA-I, LpA-I:A-II HDL and CHD-risk: The Framingham Offspring Study and the Veterans Affairs HDL Intervention Trial
Asztalos, B. F., Demissie, S., Cupples, L. A., Collins, D. E., Cox, C. E., Horvath, K. V., Bloomfield, H. E., Robins, S. J., & Schaefer, E. J. (2005) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2005.10.018 · Cited by 42
Self-citation
Effect of insulin analog initiation therapy on LDL/HDL subfraction profile and HDL associated enzymes in type 2 diabetic patients
Aslan, I., Küçüksayan, E., & Aslan, M. (2013) · Lipids in Health and Disease · doi:10.1186/1476-511x-12-54 · Cited by 40
Fenofibrate, HDL, and cardiovascular disease in Type-2 diabetes: The DAIS trial
Tsunoda, F., Asztalos, I. B., Horvath, K. V., Steiner, G. A., Schaefer, E. J., & Asztalos, B. F. (2016) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2016.01.028 · Cited by 40
Self-citation
Dysfunctional high-density lipoprotein: an updated review
Ouyang, F. W., Chiang, H., Hsu, W., Tsai, M.-H., Huang, C.-Y., Remaley, A. T., Akyol, Ö., & Chen, C. (2025) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2025.1713387 · Cited by 40
High-density lipoprotein subpopulation profiles in lipoprotein lipase and hepatic lipase deficiency
Tani, M., Horvath, K. V., Lamarche, B., Couture, P., Burnett, J. R., Schaefer, E. J., & Asztalos, B. F. (2016) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2016.08.014 · Cited by 39
Self-citation
Influence of HDL particles on cell-cholesterol efflux under various pathological conditions
Asztalos, B. F., Horvath, K. V., Mehan, M. R., Yokota, Y., & Schaefer, E. J. (2017) · Journal of Lipid Research · doi:10.1194/jlr.m075648 · Cited by 39
Self-citation
Increasing High-Density Lipoprotein Cholesterol, Inhibition of Cholesteryl Ester Transfer Protein, and Heart Disease Risk Reduction
Schaefer, E. J., & Asztalos, B. F. (2007) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2007.08.010 · Cited by 40
Self-citation
Comparison of high-density and low-density lipoprotein cholesterol subclasses and sizes in asian indian women with caucasian women from the framingham offspring study
Bhalodkar, N. C., Blum, S., Rana, T., Kitchappa, R., Bhalodkar, A., & Enas, E. A. (2005) · Clinical Cardiology · doi:10.1002/clc.4960280510 · Cited by 38
HDL proteomics: pot of gold or Pandora’s box?
Reilly, M. P., & Tall, A. R. (2007) · Journal of Clinical Investigation · doi:10.1172/jci31608 · Cited by 38
Tanshinone IIA affects the HDL subfractions distribution not serum lipid levels: Involving in intake and efflux of cholesterol
Jia, L., Zhang, N., Xu, Y., Chen, W., Zhu, M.-L., Song, N., Ren, L., Cao, H., Wang, J., & Yang, G. (2016) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2016.01.001 · Cited by 37
Association of HDL-C and apolipoprotein A-I with the risk of type 2 diabetes in subjects with impaired fasting glucose
Hwang, Y., Ahn, H. Y., Park, H., & Park, C. (2014) · European Journal of Endocrinology · doi:10.1530/eje-14-0195 · Cited by 37
Predictive value of different HDL particles for the protection against or risk of coronary heart disease
Rye, K., & Barter, P. J. (2011) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2011.10.012 · Cited by 36
The “beta-clasp” model of apolipoprotein A-I — A lipid-free solution structure determined by electron paramagnetic resonance spectroscopy
Lagerstedt, J. O., Budamagunta, M. S., Liu, G. S., DeValle, N., Voss, J. C., & Oda, M. N. (2012) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2011.12.010 · Cited by 36
Reduced HDL function in children and young adults with type 1 diabetes
Heier, M., Borja, M. S., Brunborg, C., Seljeflot, I., Margeirsdottir, H. D., Hanssen, K. F., Dahl‐Jørgensen, K., & Oda, M. N. (2017) · Cardiovascular Diabetology · doi:10.1186/s12933-017-0570-2 · Cited by 38
Clinical presentation, laboratory values, and coronary heart disease risk in marked high-density lipoprotein-deficiency states.
Santos, R. D., Asztalos, B., Martinez, L., Miname, M., Polisecki, E., & Schaefer, E. (2008) · Journal of Clinical Lipidology · doi:10.1016/j.jacl.2008.06.002 · Cited by 40
Self-citation
Effects of intensive atorvastatin and rosuvastatin treatment on apolipoprotein B-48 and remnant lipoprotein cholesterol levels
Otokozawa, S., Ai, M., van Himbergen, T. M., Asztalos, B. F., Tanaka, A., Stein, E. A., Jones, P. H., & Schaefer, E. J. (2008) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2008.11.001 · Cited by 36
Self-citation

Authors: Asztalos, B. F., Cupples, L. A., Demissie, S., Horvath, K. V., Cox, C. E., Batista, M. C., & Schaefer, E. J.
Affiliations: Boston University (US)
ORCID: Asztalos, Bela F.
Cupples, L. Adrienne
Demissie, Serkalem
Batista, Marcelo C.
Schaefer, Ernst J.
Venue: Arteriosclerosis, Thrombosis, and Vascular Biology
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2004-11
Volume: 24
Issue: 11
Pages: 2181-2187
ISSN: 1079-5642 (ISSN-L)
1524-4636
DOI: 10.1161/01.atv.0000146325.93749.a8
OpenAlex: W2103507414
Cited by: 298
References: 30
Citations by year: 2025: 9 · 2024: 5 · 2023: 8 · 2022: 7 · 2021: 4 · 2020: 5 · 2019: 4 · 2018: 16 · 2017: 10 · 2016: 17 · 2015: 14 · 2014: 17 · 2013: 23 · 2012: 27
FWCI: 15.79
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Arteriosclerosis Thrombosis and Vascular Biology (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health (n01hc038038-022)
National Heart, Lung, and Blood Institute (HC 38038, HL54776, HL 64738, N01-HC, N01-HC-38038, R01HL054776, R01HL064738)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipoproteins and Cardiovascular Health
Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Cholesterol and Lipid Metabolism
Life Sciences › Biochemistry, Genetics and Molecular Biology › Clinical Biochemistry › Paraoxonase enzyme and polymorphisms
Keywords: high-density lipoprotein, HDL subpopulations, coronary artery disease, HDL cholesterol, apolipoprotein A-I, HDL heterogeneity, cardiovascular risk, Framingham Offspring Study, men
MeSH terms: Coronary Disease, Humans, Male, Prospective Studies, Risk Factors, Time, Prevalence, Apolipoprotein A-I, Observation

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

High-density lipoprotein subpopulation profile and coronary heart disease prevalence in male participants of the Framingham Offspring Study.

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks