The DOI matches its Crossref record; 60 of the 60 references it cites were found in a registry or an index.
The Transcription Factor NF-κB and the Regulation of Vascular Cell Function
Open accessAbstract
Abstract—A variety of pathophysiological situations that affect cells of the vasculature, including endothelial and smooth muscle cells, leads to the expression of genes such as adhesion molecules and chemokines that are dependent on members of the nuclear factor (NF)-κB family of transcription factors. The corresponding gene products mediate important biological functions such as immune and inflammatory reactions, smooth muscle cell proliferation, and angiogenesis. The beneficial and usually transient NF-κB–dependent gene expression may be exaggerated in pathological situations and results in damage to the vessel wall and impaired vascular cell function. In this review, we will capitalize on the favorable and adverse roles of NF-κB in the context of vascular disease, eg, chronic and localized inflammation, arteriosclerosis, and neoangiogenesis.
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Cites
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IKK-1 and IKK-2: Cytokine-Activated IκB Kinases Essential for NF-κB Activation
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Role of Transcriptional Activation of IκBα in Mediation of Immunosuppression by Glucocorticoids
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Evidence for a Potent Antiinflammatory Effect of Rosiglitazone
Mohanty, P., Aljada, A., Ghanim, H., Hofmeyer, D., Tripathy, D., Syed, T., Al-Haddad, W., Dhindsa, S., & Dandona, P. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-032103 · Cited by 379
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Metadata
- Authors
- de Martin, R., Hoeth, M., Hofer-Warbinek, R., & Schmid, J. A.
- Venue
- Arteriosclerosis, Thrombosis, and Vascular Biology
- Published
- 2000-11
- Volume
- 20
- Issue
- 11
- Pages
- E83-8
- ISSN
- 1079-5642 (ISSN-L)
- 1524-4636
- OpenAlex
- W2110277687
- Cited by
- 408
- References
- 60
- FWCI
- 5.73
- Type
- journal article
- Language
- en
- Open access
- bronze
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- de Martin, R., Hoeth, M., Hofer-Warbinek, R., & Schmid, J. A. (2000). The Transcription Factor NF-κB and the Regulation of Vascular Cell Function. Arteriosclerosis, Thrombosis, and Vascular Biology. https://doi.org/10.1161/01.atv.20.11.e83
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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