The DOI matches its Crossref record; 47 of the 47 references it cites were found in a registry or an index.
Risk factors and atherosclerotic lesions. A review of autopsy studies
Open accessAbstract
This review assesses the current status of knowledge concerning the relationship of risk factors to atherosclerotic lesions. Risk factors for atherosclerotic lesions per se need not necessarily be identical to those related to clinically overt coronary heart disease (CHD). This review is based on 1) autopsy studies where information risk factors was gathered in a retrospective fashion; and 2) autopsy studies where information on risk factors was gathered prospectively. In spite of differences in study designs and grading methods among the studies, the general findings were similar. Elevated serum cholesterol and blood pressure are positively and significantly related to atherosclerotic lesions. High density lipoprotein cholesterol is inversely related to coronary and probably also to cerebral atherosclerosis. Almost all studies indicate a significant association between cigarette smoking and degree of aortic atherosclerosis; a positive relationship between smoking and coronary atherosclerosis is found between obesity or physical activity and the degree of atherosclerosis. Data from the Community Pathology Study in New Orleans indicate that the average extent of coronary atherosclerosis in a population may be subject to changes within a relatively short period of time; these changes might be expected to parallel changes in risk factors in the population.
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Cites
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Sorted by citations
Inflammation and Atherosclerosis
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Metadata
- Authors
- Solberg, L. A., & Strong, J. P.
- Affiliations
- Oslo University Hospital (NO)
- Venue
- Arteriosclerosis: An Official Journal of the American Heart Association, Inc.
- Published
- 1983-05
- Volume
- 3
- Issue
- 3
- Pages
- 187-198
- ISSN
- 0276-5047 (ISSN-L)
- OpenAlex
- W2168514834
- Cited by
- 371
- References
- 47
- Citations by year
- 2026: 2 · 2025: 5 · 2023: 1 · 2022: 5 · 2021: 6 · 2020: 2 · 2019: 5 · 2018: 2 · 2017: 7 · 2016: 6 · 2015: 4 · 2014: 4 · 2013: 9 · 2012: 11
- FWCI
- 2.37
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Arteriosclerosis An Official Journal of the American Heart Association Inc (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (HL-08974)
- U.S. Public Health Service
- National Heart, Lung, and Blood Institute (HL08974)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipoproteins and Cardiovascular Health
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Keywords
- atherosclerosis, cardiovascular risk factors, coronary artery disease, serum cholesterol, blood pressure, HDL cholesterol, cigarette smoking, obesity, physical activity, aortic atherosclerosis, cerebral atherosclerosis, autopsy studies
- MeSH terms
- Adult, Aged, Aorta, Arteriosclerosis, Autopsy, Cerebral Arteries, Cholesterol, Coronary Disease, Coronary Vessels, Diastole, Female, Humans, Hypertension, Lipoproteins, HDL, Cholesterol, HDL, Louisiana, Male, Middle Aged, Norway, Risk, Sex Factors, Smoking, Systole, Triglycerides, Diabetes Complications
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