The DOI matches its Crossref record; 38 of the 38 references it cites were found in a registry or an index.
Emotional and Physical Precipitants of Ventricular Arrhythmia
Open accessAbstract
BACKGROUND: Observational studies have suggested that psychological stress increases the incidence of sudden cardiac death. Whether emotional or physical stressors can trigger spontaneous ventricular arrhythmias in patients at risk has not been systematically evaluated. METHODS AND RESULTS: Patients with implantable cardioverter-defibrillators (ICDs) were given diaries to record levels of defined mood states and physical activity, using a 5-point intensity scale, during 2 periods preceding spontaneously occurring ICD shocks (0 to 15 minutes and 15 minutes to 2 hours) and during control periods 1 week later. ICD-stored electrograms confirmed the rhythm at the time of shock. A total of 107 confirmed ventricular arrhythmias requiring shock were reported by 42 patients (33 men; mean age, 65 years; 78% had coronary artery disease) between August 1996 and September 1999. In the 15 minutes preceding shock, an anger level > or =3 preceded 15% of events compared with 3% of control periods (P<0.04; odds ratio, 1.83; 95% confidence intervals, 1.04 to 3.16) Other mood states (anxiety, worry, sadness, happiness, challenge, feeling in control, or interest) did not differ. Patients were more physically active preceding shock than in control periods. Anger and physical activity were independently associated with the preshock period. CONCLUSIONS: Anger and physical activity can trigger ventricular arrhythmias in patients with ICDs. Future investigations of therapies aimed at blocking a response to these stressors may decrease ventricular arrhythmias and shocks in these patients.
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“In addition, the adrenergic hyperactivation connected with intense emotions and anxiety can, in itself, predispose the patient to supraventricular and/or ventricular arrhythmias.25 -27”
From Management of patients with palpitations: a position paper from the European Heart Rhythm Association (2011) · cites this paper as [25]
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Zipes, D. P., Camm, A. J., Borggrefe, M., Buxton, A. E., CHAITMAN, B. R., FROMER, M. A., Gregoratos, G., Klein, G. J., Myerburg, R. J., Quiñones, M. A., et al. (2006) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2006.07.010 · Cited by 1,975
Zipes, D. P., Camm, A. J., Borggrefe, M., Buxton, A. E., Chaitman, B., Fromer, M., Gregoratos, G., Klein, G., Moss, A. J., Myerburg, R. J., et al. (2006) · Circulation · doi:10.1161/circulationaha.106.178233 · Cited by 1,080
Stress and Cardiovascular Disease: An Update on Current Knowledge
Steptoe, A., & Kivimäki, M. (2013) · Annual Review of Public Health · doi:10.1146/annurev-publhealth-031912-114452 · Cited by 879
PSYCHOSOCIAL FACTORS AND CARDIOVASCULAR DISEASES
Everson‐Rose, S. A., & Lewis, T. T. (2005) · Annual Review of Public Health · doi:10.1146/annurev.publhealth.26.021304.144542 · Cited by 838
Zipes, D. P., Camm, A. J., Borggrefe, M., Buxton, A. E., CHAITMAN, B. R., FROMER, M. A., Gregoratos, G., Klein, G. J., Moss, A. J., Myerburg, R. J., et al. (2006) · EP Europace · doi:10.1093/europace/eul108 · Cited by 741
Metadata
- Authors
- Lampert, R., Joska, T., Burg, M. M., Batsford, W. P., McPherson, C. A., & Jain, D.
- Affiliations
- Dartmouth College (US)
- Venue
- Circulation
- Published
- 2002-10
- Volume
- 106
- Issue
- 14
- Pages
- 1800-1805
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W2033555108
- Cited by
- 347
- References
- 38
- Citations by year
- 2026: 7 · 2025: 4 · 2024: 8 · 2023: 8 · 2022: 10 · 2021: 10 · 2020: 19 · 2019: 11 · 2018: 9 · 2017: 8 · 2016: 17 · 2015: 19 · 2014: 15 · 2013: 19 · 2012: 24
- FWCI
- 9.00
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Circulation (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac pacing and defibrillation studies
- Keywords
- ventricular arrhythmias, implantable cardioverter-defibrillator, sudden cardiac death, anger, emotional stress, physical activity, mood states, ICD shocks, coronary artery disease, arrhythmia triggers
- MeSH terms
- Affect, Aged, Anger, Arrhythmias, Cardiac, Electric Countershock, Emotions, Physical Exertion, Female, Heart Rate, Humans, Male, Stress, Psychological, Time Factors, Ventricular Fibrillation, Defibrillators, Implantable, Tachycardia, Ventricular, Ventricular Dysfunction
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