Cited by 750Cardiac pacing and defibrillation studiesCardiac Arrhythmias and TreatmentsCardiac electrophysiology and arrhythmias

The DOI matches its Crossref record; 27 of the 28 references it cites were found in a registry or an index.

Atrial High Rate Episodes Detected by Pacemaker Diagnostics Predict Death and Stroke: Report of the Atrial Diagnostics Ancillary Study of the MOde Selection Trial (MOST)

Open access

Glotzer, Taya V., Hellkamp, Anne S., Zimmerman, John, Sweeney, Michael O., Yee, Raymond, Marinchak, Roger, Cook, James, Paraschos, Alexander, Love, John, Radoslovich, Glauco, Lee, Kerry L., Lamas, Gervasio A.·2003·Circulation

DOI 10.1161/01.cir.0000057981.70380.45

Open this paper in CoChat — free account Open PDF

Abstract

Background— Some current pacing systems can automatically detect and record atrial tachyarrhythmias that may be asymptomatic. We prospectively studied a 312-patient (pt) subgroup of MOST (MOde Selection Trial), a 2010-patient, 6-year randomized trial of DDDR versus VVIR pacing in sinus node dysfunction (SND). The purpose of the study was to correlate atrial high rate events (AHREs) detected by pacemaker diagnostics with clinical outcomes. Methods and Results— Pacemakers were programmed to log an AHRE when the atrial rate was >220 bpm for 10 consecutive beats. Analysis was confined to patients with at least 1 AHRE duration exceeding 5 minutes. The 312 patients were median age 74 years, 55% female, and 60% had a history of SVT. 160 of 312 (51.3%) patients enrolled had at least 1 AHRE >5 minutes duration over median follow-up of 27 months. Cox proportional hazards analysis assessed the relationship of AHREs with clinical events, adjusting for prognostic variables and baseline covariates. The presence of any AHRE was an independent predictor of the following: total mortality (hazard ratio AHRE versus no AHRE and 95% confidence intervals=2.48 [1.25, 4.91], P =0.0092); death or nonfatal stroke (2.79 [1.51, 5.15], P =0.0011); and atrial fibrillation (5.93 [2.88, 12.2], P =0.0001). There was no significant effect of pacing mode on the presence or absence of AHREs. Conclusions— AHRE detected by pacemakers in patients with SND identify patients that are more than twice as likely to die or have a stroke, and 6 times as likely to develop atrial fibrillation as similar patients without AHRE.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1161/01.cir.0000057981.70380.45

Cites

27 of 27 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Nonparametric Estimation from Incomplete Observations
Kaplan, E. L., & Meier, P. (1992) · Springer series in statistics · doi:10.1007/978-1-4612-4380-9_25 · Cited by 45,239
Regression Models and Life-Tables
Cox, D. R. (1972) · Journal of the Royal Statistical Society Series B: Statistical Methodology · doi:10.1111/j.2517-6161.1972.tb00899.x · Cited by 39,793
Nonparametric Estimation from Incomplete Observations
Kaplan, E. L., & Meier, P. (1958) · Journal of the American Statistical Association · doi:10.1080/01621459.1958.10501452 · Cited by 39,158
Regression Models and Life-Tables
Cox, D. R. (1992) · Springer Series in Statistics · doi:10.1007/978-1-4612-4380-9_37 · Cited by 26,297
The Statistical Analysis of Failure Time Data.
Aitkin, M. A., Kalbfleisch, J. D., & Prentice, R. L. (1981) · Biometrics · doi:10.2307/2530581 · Cited by 9,875
Impact of Atrial Fibrillation on the Risk of Death: The Framingham Heart Study
Benjamin, E. J., Wolf, P. A., D’Agostino, R. B., Silbershatz, H., Kannel, W. B., & Levy, D. (1998) · Circulation · doi:10.1161/01.cir.98.10.946 · Cited by 4,575
Risk Factors for Stroke and Efficacy of Antithrombotic Therapy in Atrial Fibrillation
(1994) · Archives of Internal Medicine · doi:10.1001/archinte.154.13.1449 · Cited by 2,643
Atrial Fibrillation: A Major Contributor to Stroke in the Elderly: The Framingham Study
Wolf, P. A. (1987) · Archives of Internal Medicine · doi:10.1001/archinte.1987.00370090041008 · Cited by 1,108
Ventricular Pacing or Dual-Chamber Pacing for Sinus-Node Dysfunction
Lamas, G. A., Lee, K. L., Sweeney, M. O., Silverman, R., León, A. R., Yee, R. K., Marinchak, R. A., Flaker, G., SCHRON, E. B., Orav, E. J., et al. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa013040 · Cited by 994
Self-citation
Pathophysiology and Prevention of Atrial Fibrillation
Allessie, M. A., Boyden, P. A., Camm, A. J., Kléber, A. G., Lab, M. J., Legato, M. J., Rosen, M. R., Schwartz, P. J., Spooner, P. M., Wagoner, D. R. V., et al. (2001) · Circulation · doi:10.1161/01.cir.103.5.769 · Cited by 724

Show all 28 references

Research works printed but not linked: 6

10.1161/circ.98.10.946 · DOI
10.1161/circ.101.8.878 · DOI
10.1161/circ.103.5.769 · DOI
10.1001/archinte.1994.00420130036007 · DOI
10.1161/circ.89.1.8281651 · DOI
10.1161/circ.88.3.8353866 · DOI

Sorted by citations

Items 301–400 of 749

Atrial Arrhythmia Burden on Long-Term Monitoring in Asymptomatic Patients Late After Atrial Fibrillation Ablation
Winkle, R. A., Mead, R. H., Engel, G., Kong, M. H., & Patrawala, R. A. (2012) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2012.05.012 · Cited by 20
Does atrial pacing lead to atrial fibrillation in patients with sick sinus syndrome? Insights from the DANPACE trial
Hjortshøj, S. P., Riahi, S., Nielsen, J. C., Skjøth, F., Lundbye‐Christensen, S., Andersen, H., & on behalf of the DANPACE Investigators (2013) · EP Europace · doi:10.1093/europace/eut306 · Cited by 20
Current and Emerging Uses of Insertable Cardiac Monitors
Tomson, T. T., & PASSMAN, R. S. (2016) · Cardiology in Review · doi:10.1097/crd.0000000000000129 · Cited by 20
Prognostic Significance of Atrial Arrhythmias in a Primary Prevention ICD Population
Gelder, I. C. V., Phan, H., Wilkoff, B. L., BROWN, M. L., Rogers, T. B., PETERSON, B. J., & Birgersdotter-Green, U. M. (2011) · Pacing and Clinical Electrophysiology · doi:10.1111/j.1540-8159.2011.03124.x · Cited by 20
Sinus and Paced P Wave Duration and Dispersion as Predictors of Atrial Fibrillation After Pacemaker Implantation in Patients with Isolated Sick Sinus Syndrome
KRISTENSEN, L., Nielsen, J. C., Mortensen, P. T., Christensen, P. D., Vesterlund, T., Pedersen, A. K., & Andersen, H. (2004) · Pacing and Clinical Electrophysiology · doi:10.1111/j.1540-8159.2004.00494.x · Cited by 18
Predictors of Atrial Antitachycardia Pacing Efficacy in Patients Affected by Brady‐Tachy Form of Sick Sinus Syndrome and Implanted with a DDDRP Device
Boriani, G., Padeletti, L., Santini, M., Gulizia, M. M., Capucci, A., Botto, G., Ricci, R. P., Molon, G., Accogli, M., Vicentini, A., et al. (2005) · Journal of Cardiovascular Electrophysiology · doi:10.1111/j.1540-8167.2005.40716.x · Cited by 20
Stroke in Patients with Atrial Fibrillation: Epidemiology, Screening, and Prognosis
Suomalainen, O., Martinez‐Majander, N., Broman, J., Mannismäki, L., Aro, A. L., Curtze, S., Pakarinen, S., Lehto, M., & Putaala, J. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm13010030 · Cited by 21
“Notably, bridging with low-molecular weight heparins cannot be recommended before starting OAC [120].”
BackgroundInfluential
New Oral Anticoagulants in Nonvalvular Atrial Fibrillation
Fatima, U., Kulkarni, A., Stapleton, D. D., & Kaluski, E. (2016) · Clinical Cardiology · doi:10.1002/clc.22582 · Cited by 19
Comparing mid‐term outcomes of Cox‐Maze procedure and pulmonary vein isolation for atrial fibrillation after concomitant mitral valve surgery: A systematic review
Sef, D., Trkulja, V., Raja, S. G., Hooper, J., & Turina, M. I. (2022) · Journal of Cardiac Surgery · doi:10.1111/jocs.16888 · Cited by 19
Atrial High Rate Episodes in Patients with Dual‐Chamber Cardiac Implantable Electronic Devices: Unmasking Silent Atrial Fibrillation
Benezet‐Mazuecos, J., Campal, J. M. R., & Farré, J. (2014) · Pacing and Clinical Electrophysiology · doi:10.1111/pace.12428 · Cited by 19
Modelling the health benefits and economic implications of implanting dual-chamber vs. single-chamber ventricular pacemakers in the UK
Jaime, J., Ward, A., & Möller, J. (2006) · EP Europace · doi:10.1093/europace/eul042 · Cited by 19
Permanent Pacemakers and Implantable Defibrillators
McPherson, C. A., & Manthous, C. A. (2004) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200402-211up · Cited by 19
Clinical Implications of Technological Advances in Screening for Atrial Fibrillation
Singh, N., Chun, S., Hadley, D., & Froelicher, V. F. (2018) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2018.01.007 · Cited by 19
Kardiologische Diagnostik nach zerebraler Ischämie
Laufs, U., Hoppe, U. C., Rosenkranz, S., Kirchhof, P. F., Böhm, M., Diener, H., Endres, M., Grond, M., Hacke, W., Meinertz, T., et al. (2010) · Der Nervenarzt · doi:10.1007/s00115-009-2901-3 · Cited by 18
“In der TRENDSStudie (2486 Patienten mit mindestens einen zusätzlichen Risikofaktor für einen Schlaganfall) und in einer Subanalyse der MOST-Studie war dagegen eine Episodendauer von >5 min Arrhythmien, die vom Schrittmacher als Vorhofflimmern klassifiziert wurden, mit einem erhöhten Risiko für ein thrombembolisches Er…”
Background
The Pacing to Avoid Cardiac Enlargement (PACE) Trial: Clinical Background, Rationale, Design, and Implementation
Fung, J. W., Chan, J. Y., Omar, R., Hussin, A., Zhang, Q., Yip, G. W., Lam, K. H., Fang, F., & Yu, C. (2007) · Journal of Cardiovascular Electrophysiology · doi:10.1111/j.1540-8167.2007.00862.x · Cited by 19
Clinical characteristics of atrial fibrillation detected by implanted devices and its association with ICD therapy
Aizawa, Y., Takatsuki, S., Negishi, M., Kashimura, S., Katsumata, Y., Nishiyama, T., Kimura, T., Nishiyama, N., Tanimoto, Y., Tanimoto, K., et al. (2014) · International Journal of Cardiology · doi:10.1016/j.ijcard.2014.01.067 · Cited by 18
Occult atrial fibrillation in ischemic stroke
Tayal, A. H., & Callans, D. J. (2010) · Neurology · doi:10.1212/wnl.0b013e3181e19559 · Cited by 18
Cardiological evaluation after cerebral ischaemia
Laufs, U., Hoppe, U. C., Rosenkranz, S., Kirchhof, P. F., Böhm, M., Diener, H., Endres, M., Grond, M., Hacke, W., Meinertz, T., et al. (2010) · Clinical Research in Cardiology · doi:10.1007/s00392-010-0200-4 · Cited by 18
“contrast, in the TRENDS study (2,486 patients with at least one additional risk factor for stroke) and in a sub-analysis in the MOST study, arrhythmia lasting[5 min detected by the pacemaker as atrial fibrillation was associated with an increased risk of a thromboembolic event [72, 73].”
Method
Atrial high-rate episodes: a comprehensive review
Simu, G. R., Roşu, R., Cismaru, G. L., Puiu, M., Guşetu, G., Minciună, I., Istrătoaie, S., Tomoaia, R., Zdrenghea, D. T., & Pop, D. (2021) · Cardiovascular journal of South Africa/Cardiovascular journal of Southern Africa · doi:10.5830/cvja-2020-052 · Cited by 17
“than five to six minutes were associated with an increased risk of developing clinical AF.(18) Similar results were reported later by the ASSERT study, where 16% of patients with AHRE longer than six minutes developed clinical AF.”
BackgroundResultInfluential
Diving to the foot of an iceberg: The SEARCH for undiagnosed atrial fibrillation
Lane, D. A., & Potpara, T. (2014) · Thrombosis and Haemostasis · doi:10.1160/th14-05-0437 · Cited by 17
“5-fold increased risk of subsequent stroke (31-33).”
Can we rely on machines? Device-detected atrial high rates correspond well with atrial arrhythmias in cardiac resynchronization recipients
Jędrzejczyk‐Patej, E., Lenarczyk, R., Mazurek, M., Liberska, A., Przybylska-Siedlecka, K., Podolecki, T., Kowalczyk, J. P., Sokal, A., Leopold-Jadczyk, A., Kowalski, O., et al. (2015) · EP Europace · doi:10.1093/europace/euv095 · Cited by 17
Characteristics and Prognosis of Pacemaker-Identified New-Onset Atrial Fibrillation in Japanese People
Ogino, Y., Ishikawa, T., Ishigami, T., Matsumoto, K., Hosoda, J., Iguchi, K., Matsushita, H., Taguchi, Y., Horiguchi, Y., & Kimura, K. (2017) · Circulation Journal · doi:10.1253/circj.cj-16-1018 · Cited by 17
Interatrial septum versus right atrial appendage pacing for prevention of atrial fibrillation
Zhang, L., Jiang, H., Wang, W., Bai, J.-Y., Liang, Y., Su, Y., & Ge, J. (2017) · Herz · doi:10.1007/s00059-017-4589-7 · Cited by 17
Left Atrial Diameter and Atrial Ectopic Burden in Patients with Embolic Stroke of Undetermined Source: Risk Stratification of Atrial Fibrillation with Insertable Cardiac Monitor Analysis
Lee, J. H., Moon, I. T., Cho, Y., Kim, J. Y., Kang, J., Kim, B. J., Han, M., Oh, I., & Bae, H. (2021) · Journal of Clinical Neurology · doi:10.3988/jcn.2021.17.2.213 · Cited by 17
When Low-Risk Atrial Fibrillation Is Not So Low Risk
Steinberg, B. A., & Piccini, J. P. (2018) · JAMA Cardiology · doi:10.1001/jamacardio.2018.1205 · Cited by 17
The usefulness of minimal ventricular pacing and preventive AF algorithms in the treatment of PAF: the ‘MinVPace’ study
Veasey, R. A., Arya, A., Freemantle, N., Silberbauer, J., Patel, N., Lloyd, G., & Sulke, A. N. (2010) · Journal of Interventional Cardiac Electrophysiology · doi:10.1007/s10840-009-9461-0 · Cited by 16
“The presence of episodes as short as 5 min has been reported to be a powerful independent predictor of stroke, death and persistent AF [41], and it is interesting that the SAVEFig.”
Background
Usefulness of statins in preventing atrial fibrillation in patients with permanent pacemaker: a systematic review
Santangeli, P., Ferrante, G., Pelargonio, G., Russo, A. D., Casella, M., Bartoletti, S., Biase, L. D., Crea, F., & Natale, A. (2010) · EP Europace · doi:10.1093/europace/euq044 · Cited by 16
Improvement of P wave dispersion after cardiac resynchronization therapy for heart failure
Ding, L., Hua, W., Zhang, S., Chu, J., Chen, K., Wang, F., & Chen, X. (2009) · Journal of Electrocardiology · doi:10.1016/j.jelectrocard.2009.02.005 · Cited by 16
Asymptomatic atrial fibrillation in patients with atrial fibrillation and implanted pacemaker
Witkowski, M., Bissinger, A., Grycewicz, T., & Lubiński, A. (2016) · International Journal of Cardiology · doi:10.1016/j.ijcard.2016.10.097 · Cited by 16
The Impact of Atrial Fibrillation Clinical Subtype on Mortality
Leung, M., van Rosendael, P. J., Abou, R., Marsan, N. A., Leung, D. Y., Delgado, V., & Bax, J. J. (2017) · JACC. Clinical electrophysiology · doi:10.1016/j.jacep.2017.09.002 · Cited by 16
Pacemaker-detected atrial fibrillation burden and risk of ischemic stroke or thromboembolic events—A cohort study
Chu, S., Jiang, J., Wang, Y., Sheng, Q., Zhou, J., & Ding, Y. (2019) · Heart & Lung · doi:10.1016/j.hrtlng.2019.07.007 · Cited by 16
Altered Expression of Circadian Clock Genes in Patients with Atrial Fibrillation Is Associated with Atrial High-Rate Episodes and Left Atrial Remodeling
Chen, Y., Chuang, J., Wang, H., Chen, H., Liu, W., & Yang, M. (2021) · Diagnostics · doi:10.3390/diagnostics11010090 · Cited by 16
Sinus Node Dysfunction
Sathnur, N., Ebin, E. M., & Benditt, D. G. (2023) · Cardiology Clinics · doi:10.1016/j.ccl.2023.03.013 · Cited by 16
Minimizing right ventricular pacing: A new paradigm for cardiac pacing in sinus node dysfunction
Sweeney, M. O. (2007) · American Heart Journal · doi:10.1016/j.ahj.2007.01.019 · Cited by 16
Self-citation
Interatrial Mechanical Dyssynchrony Worsened Atrial Mechanical Function in Sinus Node Disease With or Without Paroxysmal Atrial Fibrillation
Wang, M., Lau, C., ZHANG, X. H., Siu, C., Lee, K. L., Yan, G., Yue, W. S., & Tse, H. (2009) · Journal of Cardiovascular Electrophysiology · doi:10.1111/j.1540-8167.2009.01547.x · Cited by 16
Self-citation
2021 ISHNE/HRS/EHRA/APHRS Collaborative Statement on mHealth in Arrhythmia Management: Digital Medical Tools for Heart Rhythm Professionals
Varma, N., Cygankiewicz, I., Turakhia, M. P., Heidbuchel, H., Hu, Y., Chen, L. Y., Couderc, J.-P., Cronin, E. M., Estep, J. D., Grieten, L., et al. (2021) · Cardiovascular Digital Health Journal · doi:10.1016/j.cvdhj.2020.11.004 · Cited by 16
“Device-detected, “subclinical” atrial high-rate episodes (AHRE) lasting 6 minutes to 24 hours are associated with increased stroke risk, but the absolute risk is considerably lower than expected based on risk factors alone (Glotzer 2003, Healey 2012, van Gelder 2017).”
Background
Overdrive Versus Conventional or Closed‐Loop Rate Modulation Pacing in the Prevention of Atrial Tachyarrhythmias in Brady‐Tachy Syndrome: On Behalf of the Burden II Study Group
PUGLISI, A., Favale, S., Scipione, P., Melissano, D., Pavía, L., ASCANI, F., ELIA, M., Scaccia, A., Sagone, A., Castaldi, B., et al. (2008) · Pacing and Clinical Electrophysiology · doi:10.1111/j.1540-8159.2008.01208.x · Cited by 15
Use of Smart Technology for the Early Diagnosis of Complications After Cardiac Surgery: The Box 2.0 Study Protocol
Biersteker, T. E., Boogers, M. J., van Wijngaarden, R. A. F. D. L., Groenwold, R. H. H., Trines, S. A. I. P., van Alem, A. P., Kirchhof, C. J. H. J., van Hof, N., Klautz, R. J. M., Schalij, M. J., et al. (2020) · JMIR Research Protocols · doi:10.2196/16326 · Cited by 15
“Recent studies have found that, when using AF detection devices, prolonged episodes of AF, atrial flutter, or atrial tachycardia (lasting over 5 minutes in the MOST study and over 6 minutes in the ASSERT study) are independently associated with an increased risk of stroke [47,48].”
Background
A Review of Biomarkers for Ischemic Stroke Evaluation in Patients With Non-valvular Atrial Fibrillation
Shang, L., Zhang, L., Guo, Y., Sun, H., Zhang, X., Bo, Y., Zhou, X., & Tang, B. (2021) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2021.682538 · Cited by 15
Emerging Implantable-Device Technology for Patients at the Intersection of Electrophysiology and Heart Failure Interdisciplinary Care
Mastoris, I., Spall, H. G. C. V., Sheldon, S. H., Pimentel, R., Steinkamp, L., Shah, Z. I., Al‐Khatib, S. M., Singh, J. P., & Sauer, A. J. (2021) · Journal of Cardiac Failure · doi:10.1016/j.cardfail.2021.11.006 · Cited by 15
Pacing-induced cardiomyopathy: pathophysiological insights through matrix metalloproteinases
Ahmed, F. Z., Khattar, R. S., Zaidi, A. M., Neyses, L., Oceandy, D., & Mamas, M. A. (2013) · Heart Failure Reviews · doi:10.1007/s10741-013-9390-y · Cited by 15
“Despite apparently preserved baseline LV systolic function, 9 % of those who receive chronic RV pacing may progress to develop significant pacing-induced LV dysfunction within 12-months of implantation, while others paced for many years do not [5, 17–19].”
Background
Randomized comparison between Ramp and Burst+ atrial antitachycardia pacing therapies in patients suffering from sinus node disease and atrial fibrillation and implanted with a DDDRP device
Gulizia, M. M., Mangiameli, S., Orazi, S., Chiarandà, G., Boriani, G., Piccione, G., Giovanni, N. D., Colletti, A., Puntrello, C., Butera, G., et al. (2006) · EP Europace · doi:10.1093/europace/eul055 · Cited by 15
Daily distribution of atrial arrhythmic episodes in sick sinus syndrome patients: implications for atrial arrhythmia monitoring
Capucci, A., Calcagnini, G., Mattei, E., Triventi, M., Bartolini, P., BIANCALANA, G., Gargaro, A., Puglisi, A., & Censi, F. (2012) · EP Europace · doi:10.1093/europace/eus038 · Cited by 15
Detection of Atrial Fibrillation by Permanent Pacemakers: Observations from the STOP AF Trial
Plummer, C., & McComb, J. M. (2003) · Cardiac Electrophysiology Review · doi:10.1023/b:cepr.0000023133.43829.9a · Cited by 15
Smart devices for a smart detection of atrial fibrillation
Benezet‐Mazuecos, J., García-Talavera, C. S., & Campal, J. M. R. (2018) · Journal of Thoracic Disease · doi:10.21037/jtd.2018.08.138 · Cited by 15
Continuous Cardiac Monitoring around Atrial Fibrillation Ablation: Insights on Clinical Classifications and End Points
Dekker, L., Pokushalov, E. A., Sanders, P., Lindborg, K. A., Maus, B., & Pürerfellner, H. (2016) · Pacing and Clinical Electrophysiology · doi:10.1111/pace.12897 · Cited by 14
Pacemaker Detected Prolonged Atrial High Rate Episodes – Incidence, Predictors And Implications; A Retrospective Observational Study
Mathen, P. G., & Chase, D. (2020) · Journal of the Saudi Heart Association · doi:10.37616/2212-5043.1064 · Cited by 14
2021 ISHNE / HRS / EHRA / APHRS Collaborative Statement on mHealth in Arrhythmia Management: Digital Medical Tools for Heart Rhythm Professionals
Varma, N., Cygankiewicz, I., Turakhia, M. P., Heidbüchel, H., Hu, Y., Chen, L. Y., Couderc, J., Cronin, E. M., Estep, J. D., Grieten, L., et al. (2021) · European Heart Journal - Digital Health · doi:10.1093/ehjdh/ztab001 · Cited by 17
Improving Atrial Fibrillation Detection in Patients with Implantable Cardiac Devices by Means of a Remote Monitoring and Management Application
Zoppo, F., Facchin, D., Molon, G., Zanotto, G., Catanzariti, D., Rossillo, A., Baccillieri, S., MENARD, C., COMISSO, J., Gentili, A., et al. (2014) · Pacing and Clinical Electrophysiology · doi:10.1111/pace.12474 · Cited by 14
“Specifically, cardiologists were requested to state (1) whether, during the current evaluation, AF was considered clinically relevant; (2) whether the patient was then regarded as a candidate for OAC therapy; (3) whether OAC was proposed to the patient; and (4) whether any OAC contraindications applied.”
Background
Incidence and Characteristics of Far-Field R-Wave Sensing in Low Right Atrial Septum Pacing
Minamiguchi, H., Abe, H., Kohno, R., Oginosawa, Y., Tamura, M., Takeuchi, M., Nagatomo, T., & Otsuji, Y. (2011) · Circulation Journal · doi:10.1253/circj.cj-11-0745 · Cited by 14
“3 mV was significantly lowered by the implantation of bipolar atrial leads with narrow tip-ring interelectrode spacing, and (3) the presence of LVH on 12-lead ECG, and the use of bipolar atrial leads with a wide tip-ring interelectrode spacing were both independent predictors of FFRW sensing in the LAS region.”
Background
Prevalence of conduction delay of the right atrium in patients with SSS: implications for pacing site selection
Verlato, R., Zanon, F., Bertaglia, E., Turrini, P., Baccillieri, S., Baracca, E., Bongiorni, M. G., Zampiero, A., Zonzin, P., Pascotto, P., et al. (2007) · Journal of Cardiovascular Medicine · doi:10.2459/jcm.0b013e32801105c7 · Cited by 14
Clinical Impact of Oral Anticoagulation in Patients with Atrial High-rate Episodes
Marinheiro, R., Parreira, L., Amador, P., Lopes, C., Fernandes, A. S., Mesquita, D., Farinha, J., Fonseca, M., Duarte, T., & Caria, R. (2019) · Journal of Stroke and Cerebrovascular Diseases · doi:10.1016/j.jstrokecerebrovasdis.2018.12.019 · Cited by 14
Holter monitoring to detect silent atrial fibrillation in high-risk subjects: the Perugia General Practitioner Study
Salvatori, V., Becattini, C., Laureti, S., Baglioni, G., Germini, F., Grilli, P., Guercini, F., Filippucci, E., & Agnelli, G. (2015) · Internal and Emergency Medicine · doi:10.1007/s11739-015-1241-5 · Cited by 14
Charakterisierung der Vorhofflimmerlast mittels Wearables
Betz, K., Linz, D., Duncker, D., & Hillmann, H. A. K. (2024) · Herzschrittmachertherapie + Elektrophysiologie · doi:10.1007/s00399-024-00995-2 · Cited by 13
Comparison between left bundle branch area pacing and right ventricular pacing: ventricular electromechanical synchrony and risk of atrial high-rate episodes
Yang, W., Di, B., Peng, H., & Sun, Z.-J. (2024) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2024.1267076 · Cited by 13
“To some extent, AHREs are considered a precursor to further atrial arrhythmias such as AF (20 – 22).”
Background
Performance of Atrial Fibrillation Burden Trends for Stroke Risk Stratification
Piccini, J. P., Stanelle, E. J., Johnson, C. C., Hylek, E. M., Kanwar, R., Lakkireddy, D., Mittal, S., Peacock, J. M., Russo, A. M., Soderlund, D. M., et al. (2024) · Circulation Arrhythmia and Electrophysiology · doi:10.1161/circep.123.012394 · Cited by 14
Duration of atrial high-rate episodes and CHA2DS2-VASc score to predict cardiovascular and cerebrovascular events in patients with dual chamber permanent pacemakers
Chen, J., & Lu, W. (2020) · Journal of Cardiology · doi:10.1016/j.jjcc.2020.08.005 · Cited by 13
Novel Predictor for New-Onset Atrial High-Rate Episode in Patients With a Dual-Chamber Pacemaker
Nishinarita, R., Niwano, S., Oikawa, J., Saito, D., Sato, T., Matsuura, G., Arakawa, Y., Kobayashi, S., Shirakawa, Y., Horiguchi, A., et al. (2021) · Circulation Reports · doi:10.1253/circrep.cr-21-0096 · Cited by 13
Combined Effect of Homocysteine and Uric Acid to Identify Patients With High Risk for Subclinical Atrial Fibrillation
Wang, S., Wei, Y., Hidru, T. H., Li, D., Wang, N., Yang, Y., Wang, Y., Yang, X., & Xia, Y. (2021) · Journal of the American Heart Association · doi:10.1161/jaha.121.021997 · Cited by 13
Serial 7-Day Electrocardiogram Patch Screening for AF in High-Risk Older Women by the CHARGE-AF Score
Lin, J. Y., Larson, J. C., Schoenberg, J., Sepulveda, A., Tinker, L., Wheeler, M. T., Albert, C. M., Manson, J. E., Wells, G., Martin, L. W., et al. (2022) · JACC. Clinical electrophysiology · doi:10.1016/j.jacep.2022.08.024 · Cited by 13
Quality of Life in Cardiac Resynchronization Recipients: Association with Response and Impact on Outcome
Lenarczyk, R., Jędrzejczyk‐Patej, E., Mazurek, M., Szulik, M., Kowalski, O., Pruszkowska, P., Sokal, A., Średniawa, B., Boidol, J., Kowalczyk, J. P., et al. (2014) · Pacing and Clinical Electrophysiology · doi:10.1111/pace.12523 · Cited by 13
“AF history 9 (11) 4 (22) 11 (14) 2 (12) 10 (15) 3 (9)”
Influential
Remote Surveillance of Implantable Cardiac Devices
Orlov, M. V., Szombathy, T., CHAUDHRY, G. M., & Haffajee, C. I. (2009) · Pacing and Clinical Electrophysiology · doi:10.1111/j.1540-8159.2009.02412.x · Cited by 13
Relevance of Monitoring Atrial Fibrillation in Clinical Practice
Lewalter, T., & Boriani, G. (2012) · Arrhythmia & Electrophysiology Review · doi:10.15420/aer.2012.1.54 · Cited by 13
The Role of Continuous Monitoring in Atrial Fibrillation Management
Camm, A. J. (2011) · Arrhythmia & Electrophysiology Review · doi:10.15420/aer.2011.3.1.48 · Cited by 15
Wearable and implantable diagnostic monitors in early assessment of atrial tachyarrhythmia burden
Healey, J. S., & Wong, J. A. (2018) · EP Europace · doi:10.1093/europace/euy246 · Cited by 14
Long-term (>10-year) clinical follow-up after young embolic stroke/TIA of undetermined source
Nassif, M., Annink, M. E., Yang, H., Rettig, T. C. D., Roos, Y. B. W. E. M., van den Brink, R., Tijssen, J. G. P., Mulder, B. J. M., de Winter, R. J., & Bouma, B. J. (2019) · International Journal of Stroke · doi:10.1177/1747493019884520 · Cited by 13
Diagnostic yield of chest and thumb ECG after cryptogenic stroke, Transient ECG Assessment in Stroke Evaluation (TEASE): an observational trial
Magnusson, P., Lyren, A., & Mattsson, G. (2020) · BMJ Open · doi:10.1136/bmjopen-2020-037573 · Cited by 14
NICE atrial fibrillation guideline snubs wearable technology: a missed opportunity?
Gala, A. R. P. B. E., Pope, M., Leo, M., Lobban, T., & Betts, T. R. (2022) · Clinical Medicine · doi:10.7861/clinmed.2021-0436 · Cited by 11
The Influence of Symptoms and Device Detected Atrial Tachyarrhythmias on Medical Management: Insights from A‐HIRATE
Ghali, J. K., Orlov, M. V., Araghi‐Niknam, M., Sherfesee, L., & Hettrick, D. A. (2007) · Pacing and Clinical Electrophysiology · doi:10.1111/j.1540-8159.2007.00772.x · Cited by 13
Evaluation of an algorithm‐guided photoplethysmography for atrial fibrillation burden using a smartwatch
Zhao, Z., Li, Q., Li, S., Guo, Q., Bo, X., Kong, X., Xia, S., Li, X., Dai, W., Guo, L., et al. (2024) · Pacing and Clinical Electrophysiology · doi:10.1111/pace.14951 · Cited by 12
2025 Clinical practice guidelines for Supraventricular tachycardias
Popov, S. V., Davtyan, K. V., Shubik, Y. V., Artyukhina, Е. А., Базаев, В. А., Batalov, R. E., Bokeria, L. A., Bubnova, M. G., Vygovsky, A. B., Sp, G., et al. (2025) · Russian Journal of Cardiology · doi:10.15829/1560-4071-2025-6448 · Cited by 12
Bayes’ Syndrome and the Opportunities for Early Anticoagulation
Baranchuk, A. M. (2017) · Northern Clinics of Istanbul · doi:10.14744/nci.2017.60251 · Cited by 11
Implantable Loop Recorders for Cryptogenic Stroke (Plus Real-World Atrial Fibrillation Detection Rate with Implantable Loop Recorders)
Musat, D. L., Milstein, N. S., & Mittal, S. (2018) · Cardiac Electrophysiology Clinics · doi:10.1016/j.ccep.2017.11.011 · Cited by 12
What to do with device‐detected atrial high‐rate episodes: Summary of the evidences
Mert, G. Ö., Kepez, A., Mert, K. U., & Görenek, B. (2021) · Pacing and Clinical Electrophysiology · doi:10.1111/pace.14428 · Cited by 11
Paroxysmal Atrial Fibrillation in Cryptogenic Stroke: an Overlooked Explanation?
Zhang, C., & Kasner, S. E. (2015) · Current Atherosclerosis Reports · doi:10.1007/s11883-015-0547-0 · Cited by 13
A Prospective Randomized Study to Assess the Efficacy of Rate and Site of Atrial Pacing on Long‐Term Development of Atrial Fibrillation
Lau, C., Wang, C., Ngarmukos, T., Kim, Y., Kong, C., Omar, R., Sriratanasathavorn, C., Munawar, M., Kam, R., LEE, K. L., et al. (2009) · Journal of Cardiovascular Electrophysiology · doi:10.1111/j.1540-8167.2009.01484.x · Cited by 12
Self-citation
How and When to Screen for Atrial Fibrillation after Stroke: Insights from Insertable Cardiac Monitoring Devices
Bridge, F., & Thijs, V. (2016) · Journal of Stroke · doi:10.5853/jos.2016.00150 · Cited by 12
Rhythm Control and Its Relation to Symptoms during the First Two Years after Radiofrequency Ablation for Atrial Fibrillation
Björkenheim, A., Brandes, A., Chemnitz, A., Magnuson, A., Edvardsson, N. G., & Poçi, D. (2016) · Pacing and Clinical Electrophysiology · doi:10.1111/pace.12916 · Cited by 12
Long-term monitoring to detect atrial fibrillation with the indwelling implantable cardiac monitors
Sanna, T. (2018) · International Journal of Stroke · doi:10.1177/1747493018790023 · Cited by 12
“4%.(10) Based on these observations, AHRE is often accepted as a surrogate for AF in the literature.”
Background
Evaluation of pacemaker telemetry as a diagnostic feature for detecting atrial tachyarrhythmias in patients with sick sinus syndrome
KRISTENSEN, L., Nielsen, J. C., Mortensen, P. T., PEDERSEN, A., & ANDERSEN, H. (2004) · EP Europace · doi:10.1016/j.eupc.2004.08.002 · Cited by 12
“However, even with atrial electrograms it is still not possible to differentiate exactly between AF, atrial flutter or atrial tachycardia, as the atrial lead only shows local atrial activity.”
Background
Predictive value of atrial high‐rate episodes for arterial stiffness and endothelial dysfunction in dual‐chamber pacemaker patients
Krishnamoorthy, S., Khoo, C. W., Lim, H. S., & Lip, G. Y. H. (2013) · European Journal of Clinical Investigation · doi:10.1111/eci.12182 · Cited by 12
Long-term reduction of atrial tachyarrhythmia recurrences in patients paced for bradycardia-tachycardia syndrome
Padeletti, L., Santini, M., Boriani, G., Botto, G., Gulizia, M. M., Molon, G., Luzzi, G., Senatore, G., Giraldi, F., Zolezzi, F., et al. (2005) · Heart Rhythm · doi:10.1016/j.hrthm.2005.07.011 · Cited by 12
Update on Bayés’ syndrome: the association between an interatrial block and supraventricular arrhythmias
Seoane, L., Cortes, M. M., & Conde, D. G. (2019) · Expert Review of Cardiovascular Therapy · doi:10.1080/14779072.2019.1577137 · Cited by 11
“Several studies have proved a good correlation between AHRE and AF, and some are already considering it a surrogate [41].”
Background
Significance and Management Strategies for Patients with Asymptomatic Atrial Fibrillation.
Majos, E., & Dąbrowski, R. (2015) · PubMed Central · doi:10.4022/jafib.1169 · Cited by 11
Can we predict new AF occurrence in single-chamber ICD patients? Insights from an observational investigation
Biffi, M., Ziacchi, M., Ricci, R. P., Facchin, D., Morani, G., Landolina, M., Lunati, M., Iacopino, S., Capucci, A., Bianchi, S., et al. (2016) · International Journal of Cardiology · doi:10.1016/j.ijcard.2016.12.126 · Cited by 11
WITHDRAWN: 2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation
Calkins, H. G., Hindricks, G., Cappato, R., Kim, Y., Saad, E., Aguinaga, L., Akar, J. G., Badhwar, V., Brugada, J., Camm, A. J., et al. (2017) · Journal of Arrhythmia · doi:10.1016/j.joa.2017.07.001 · Cited by 11
Atrial fibrillation case finding in over 65 s with cardiovascular risk factors – Results of initial Scottish clinical experience
Grubb, N. R., Elder, D. H. J., Broadhurst, P., Reoch, A., Tassie, E., & Neilson, A. R. (2019) · International Journal of Cardiology · doi:10.1016/j.ijcard.2019.03.062 · Cited by 11
Thromboembolic risks associated with paroxysmal and persistent atrial fibrillation in Asian patients: a report from the Chinese atrial fibrillation registry
Wang, Y., Ma, C., Du, X., He, L., Li, J., Wang, G., Wen, D., Dong, J., Pan, J., & Lip, G. Y. H. (2019) · BMC Cardiovascular Disorders · doi:10.1186/s12872-019-1260-7 · Cited by 11
Concomitant surgical ablation for treatment of atrial fibrillation in patients undergoing cardiac surgery
Dominici, C., & Chello, M. (2022) · Reviews in Cardiovascular Medicine · doi:10.31083/j.rcm2303101 · Cited by 11
Assessment of Left Atrial Structure and Function by Echocardiography in Atrial Fibrillation
Ji, M., He, L., Gao, L., Lin, Y., Xie, M., & Li, Y. (2022) · Diagnostics · doi:10.3390/diagnostics12081898 · Cited by 12
“The more time spent in paroxysmal AF each day is associated with higher risk of thromboembolism [77].”
Background
An Update On Insertable Cardiac Monitors: Examining the Latest Clinical Evidence and Technology for Arrhythmia Management
Olsen, F. J., Biering‐Sørensen, T., & Krieger, D. W. (2015) · Future Cardiology · doi:10.2217/fca.15.15 · Cited by 11
Paroxysmal atrial fibrillation after ischemic stroke: how should we hunt for it?
Abdul‐Rahim, A. H., & Lees, K. R. (2013) · Expert Review of Cardiovascular Therapy · doi:10.1586/erc.13.21 · Cited by 11
Methods, accuracy and clinical implications of atrial fibrillation detection by cardiac implantable electronic devices
Solari, D., Bertero, E., Miceli, R., Brunelli, C., Ameri, P., & Canepa, M. (2017) · International Journal of Cardiology · doi:10.1016/j.ijcard.2016.12.189 · Cited by 11
Stroke prevention in atrial fibrillation: Closing the gap
Pokorney, S. D., Gersh, B. J., Ahmad, A., Al‐Khatib, S. M., Blank, M. J., Coylewright, M. J., DiBattiste, P. M., Healey, J. S., Hedrich, O., Hylek, E. M., et al. (2018) · American Heart Journal · doi:10.1016/j.ahj.2018.10.004 · Cited by 11
Analyses of risk factors and prognosis for new-onset atrial fibrillation in elderly patients after dual-chamber pacemaker implantation.
Chen, X.-L., Ren, X., Liang, Z., Han, Z.-H., Zhang, T., & Luo, Z. (2018) · Europe PMC (PubMed Central) · doi:10.11909/j.issn.1671-5411.2018.10.008 · Cited by 11
Efficacy of Catheter Ablation for Atrial Fibrillation in Patients with a Permanent Pacemaker for Sick Sinus Syndrome
Wu, J., Dong, J., Sang, C., Tang, R., Li, X., & Ma, C. (2013) · Internal Medicine · doi:10.2169/internalmedicine.52.0982 · Cited by 11
“Recent studies have shown that atrial fibrillation (AF) is the most frequent tachyarrhythmia in patients with a permanent PM, occurring in up to 65% of patients with a PM for the treatment of SSS (2, 3).”
Background
The Effect of Bipole Tip-to-Ring Distance in Atrial Electrodes upon Atrial Tachyarrhythmia Sensing Capability in Modern Dual-Chamber Pacemakers
Silberbauer, J., Arya, A., Veasey, R. A., Boodhoo, L. E., KAMALVAND, K., O’NUNAIN, S., Hildick‐Smith, D., Paul, V., Patel, N., Lloyd, G., et al. (2009) · Pacing and Clinical Electrophysiology · doi:10.1111/j.1540-8159.2009.02576.x · Cited by 11
Forecasting imminent atrial fibrillation in long-term electrocardiogram recordings
Rooney, S. R., Kaufman, R., Murugan, R., KASHANI, K. B., Pinsky, M. R., Al‐Zaiti, S. S., Dubrawski, A. W., Clermont, G., & Miller, J. K. (2023) · Journal of Electrocardiology · doi:10.1016/j.jelectrocard.2023.08.011 · Cited by 13
Does asymptomatic atrial fibrillation exist?
Carneiro, H. A., & Knight, B. P. (2023) · Journal of Cardiovascular Electrophysiology · doi:10.1111/jce.16108 · Cited by 11
“89 In the TRENDS study (A Prospective Study of the Clinical Significance of Atrial Arrhythmias Detected by Implanted Device Diagnostics), a high burden of AHRE (defined as daily burden of ≥ 5.5 h in the preceding 30 ‐ day period) doubled the risk of thromboembolism.”
BackgroundInfluential
Remote Monitoring of Cardiovascular Implantable Electronic Devices: New Questions Raised
Joglar, J. A. (2009) · Pacing and Clinical Electrophysiology · doi:10.1111/j.1540-8159.2009.02546.x · Cited by 10

Authors: Glotzer, T. V., Hellkamp, A. S., Zimmerman, J., Sweeney, M. O., Yee, R., Marinchak, R., Cook, J., Paraschos, A., Love, J., Radoslovich, G., Lee, K. L., & Lamas, G. A.
Affiliations: Brigham and Women's Hospital (US)
ORCID: Glotzer, Taya V.
Hellkamp, Anne S.
Zimmerman, John
Yee, Raymond
Lamas, Gervasio A.
Venue: Circulation
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2003-04
Volume: 107
Issue: 12
Pages: 1614-1619
ISSN: 0009-7322 (ISSN-L)
1524-4539
DOI: 10.1161/01.cir.0000057981.70380.45
OpenAlex: W2149989524
Cited by: 750
References: 28
Citations by year: 2026: 16 · 2025: 21 · 2024: 31 · 2023: 26 · 2022: 23 · 2021: 50 · 2020: 38 · 2019: 50 · 2018: 52 · 2017: 64 · 2016: 56 · 2015: 46 · 2014: 44 · 2013: 32 · 2012: 34
FWCI: 12.56
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Circulation (publishedVersion)
PubMed (publishedVersion)
Funders: Medtronic
National Institutes of Health (5u01hl053973-05, 5u01hl055981-05)
National Heart, Lung, and Blood Institute (HL 53973, U01HL049804, U01 HL 53973, U01-HL-49804, U01-HL-55981)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac pacing and defibrillation studies
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Arrhythmias and Treatments
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
Keywords: atrial high-rate episodes, atrial tachyarrhythmia, sick sinus syndrome, DDDR pacing, VVIR pacing, mode choice, atrial fibrillation, mortality, stroke, prognostic factors, asymptomatic arrhythmia
MeSH terms: Adult, Aged, Arrhythmias, Cardiac, Arrhythmia, Sinus, Atrial Fibrillation, Cardiac Pacing, Artificial, Female, Heart Atria, Humans, Male, Middle Aged, Electrocardiography, Ambulatory, Stroke

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Atrial High Rate Episodes Detected by Pacemaker Diagnostics Predict Death and Stroke: Report of the Atrial Diagnostics Ancillary Study of the MOde Selection Trial (MOST)

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks