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Cited by 357

The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.

Therapeutic Angiogenesis and Vasculogenesis for Ischemic Disease: Part I: Angiogenic Cytokines

Open access
Losordo, Douglas W., Dimmeler, Stefanie·2004·Circulation

Abstract

D eprivation of oxygen and nutrients provides a serious threat for tissue viability.Nature's response to the development of profound tissue ischemia includes the upregulation of angiogenic growth factors and mobilization of circulating cellular elements that together enable development of an accessory vasculature. 1 The involved paradigm, not surprisingly, recapitulates many aspects of embryonic circulatory development.Multiple angiogenic factors and inhibitors have been implicated in the formation and correct patterning of functional blood vessels.Although hampered by several ambiguous clinical trials, transfer of genes encoding for proangiogenic factors is still an important therapeutic option to induce vascular growth after critical ischemia.Recent studies provide further evidence that neovascularization is regulated by infiltrating circulation cells, including bone marrow-derived endothelial progenitor cells or inflammatory cells.The use of "cell therapy" for therapeutic vasculogenesis will be discussed in the second part of this review article.

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Crossref · 10.1161/01.cir.0000128595.79378.fa

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Metadata

Authors
Losordo, D. W., & Dimmeler, S.
Venue
Circulation
Published
2004-06
Volume
109
Issue
21
Pages
2487-2491
ISSN
  • 0009-7322 (ISSN-L)
  • 1524-4539
OpenAlex
W2112804253
Cited by
357
References
7
FWCI
8.86
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Therapeutic Angiogenesis and Vasculogenesis for Ischemic Disease: Part I: Angiogenic Cytokines. https://app.cochat.ai/papers/10.1161/01.cir.0000128595.79378.fa
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Losordo, D. W., & Dimmeler, S. (2004). Therapeutic Angiogenesis and Vasculogenesis for Ischemic Disease: Part I: Angiogenic Cytokines. Circulation. https://doi.org/10.1161/01.cir.0000128595.79378.fa

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.