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Cited by 368

The DOI matches its Crossref record; 15 of the 15 references it cites were found in a registry or an index.

Alterations in the Local Myocardial Motion Pattern in Patients Suffering From Pressure Overload Due to Aortic Stenosis

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Stuber, M., Scheidegger, M. B., Fischer, S. E., Nagel, E., Steinemann, F., Hess, O. M., Boesiger, P.·1999·Circulation

Abstract

Background —MR tissue tagging allows the noninvasive assessment of the locally and temporally resolved motion pattern of the left ventricle. Alterations in cardiac torsion and diastolic relaxation of the left ventricle were studied in patients with aortic stenosis and were compared with those of healthy control subjects and championship rowers with physiological volume-overload hypertrophy. Methods and Results —Twelve aortic stenosis patients, 11 healthy control subjects with normal left ventricular function, and 11 world-championship rowers were investigated for systolic and diastolic heart wall motion on a basal and an apical level of the myocardium. Systolic torsion and untwisting during diastole were examined by use of a novel tagging technique (CSPAMM) that provides access to systolic and diastolic motion data. In the healthy heart, the left ventricle performs a systolic wringing motion, with a counterclockwise rotation at the apex and a clockwise rotation at the base. Apical untwisting precedes diastolic filling. In the athlete’s heart, torsion and untwisting remain unchanged compared with those of the control subjects. In aortic stenosis patients, torsion is significantly increased and diastolic apical untwisting is prolonged compared with those of control subjects or athletes. Conclusions —Torsional behavior as observed in pressure- and volume-overloaded hearts is consistent with current theoretical findings. A delayed diastolic untwisting in the pressure-overloaded hearts of the patients may contribute to a tendency toward diastolic dysfunction.

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Metadata

Authors
Stuber, M., Scheidegger, M. B., Fischer, S. E., Nagel, E., Steinemann, F., Hess, O. M., & Boesiger, P.
Venue
Circulation
Published
1999-07-27
Volume
100
Issue
4
Pages
361-368
ISSN
  • 0009-7322 (ISSN-L)
  • 1524-4539
OpenAlex
W2012826915
Cited by
368
References
15
FWCI
10.41
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Alterations in the Local Myocardial Motion Pattern in Patients Suffering From Pressure Overload Due to Aortic Stenosis. https://app.cochat.ai/papers/10.1161/01.cir.100.4.361
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Stuber, M., Scheidegger, M. B., Fischer, S. E., Nagel, E., Steinemann, F., Hess, O. M., & Boesiger, P. (1999). Alterations in the Local Myocardial Motion Pattern in Patients Suffering From Pressure Overload Due to Aortic Stenosis. Circulation. https://doi.org/10.1161/01.cir.100.4.361

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