The DOI matches its Crossref record; 20 of the 20 references it cites were found in a registry or an index.
Relation of Body Weight to Development of Coronary Heart Disease: The Framingham Study
Abstract
Interrelationships between weight change, serum cholesterol, blood pressure levels, and the risk of developing coronary heart disease have been explored in 5,127 men and women who have been followed over 12 years for signs of initial development of coronary heart disease. Antecedent relative weight and weight gain after age 25 years proved to be strongly related to risk of angina pectoris and sudden death but were unassociated with development of myocardial infarction. An excess risk of angina pectoris and sudden death appeared to exist in obese men both with and without elevations of blood pressure and serum cholesterol, indicating an independent contribution of obesity to the rate of development of these manifestations of coronary heart disease. Unless accompanied by an increase in blood pressure and serum cholesterol level, obesity appeared to play a negligible role in women. Subjects with both these predisposing factors and obesity had a pronounced increase in risk, greater than that associated with either factor alone. The data suggest that overweight may be instrumental in bringing out symptoms of angina pectoris or in precipitating sudden death by imposing an increased workload on a heart with an already compromised coronary circulation.
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Cites
Epidemiological approaches to heart disease: the Framingham study
Dawber, T. R., Meadors, G. F., & Moore, F. E. (1951) · American Journal of Public Health and the Nations Health · doi:10.2105/ajph.41.3.279 · Cited by 2,148
Self-citationKANNEL, W. B., DAWBER, T. R., KAGAN, A., REVOTSKIE, N., & STOKES, J. (1961) · Annals of Internal Medicine · doi:10.7326/0003-4819-55-1-33 · Cited by 1,837
Self-citationA Longitudinal Study of Coronary Heart Disease
PAUL, O., LEPPER, M. H., PHELAN, W. H., DUPERTUIS, G. W., MACMILLAN, A., MCKEAN, H., & PARK, H. (1963) · Circulation · doi:10.1161/01.cir.28.1.20 · Cited by 610
Coronary Heart Disease among Minnesota Business and Professional Men Followed Fifteen Years
KEYS, A., TAYLOR, H. L., BLACKBURN, H., BROZEK, J., ANDERSON, J. T., & SIMONSON, E. (1963) · Circulation · doi:10.1161/01.cir.28.3.381 · Cited by 296
Coronary artery disease in men eighteen to thirty-nine years of age
Yater, W. M., Traum, A. H., Brown, W. G., Fitzgerald, R. P., Geisler, M. A., & Wilcox, B. B. (1948) · American Heart Journal · doi:10.1016/0002-8703(48)90334-2 · Cited by 280
Blood volume, cardiac output, and distribution of systemic blood flow in extreme obesity.
Jk, A., Dennis, E. W., SMITH, W. G., Amad, K. H., DUNCAN, W. C., & AUSTIN, R. C. (1962) · PubMed · Cited by 264
Coronary artery disease in men eighteen to thirtynine years of age
Yater, W. M., Traum, A. H., Brown, W. G., Fitzgerald, R. P., Geisler, M. A., & Wilcox, B. B. (1948) · American Heart Journal · doi:10.1016/0002-8703(48)90235-x · Cited by 233
Stamler, J., Lindberg, H. A., Berkson, D. M., Shaffer, A., Miller, W., & Poindexter, A. (1960) · Journal of Chronic Diseases · doi:10.1016/0021-9681(60)90046-1 · Cited by 225
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Self-citationTHE RELATIONSHIP OF CORONARY THROMBOSIS TO CORONARY ATHEROSCLEROSIS AND ISCHEMIC HEART DISEASE
Spain, D. M., & BRADESS, V. A. (1960) · The American Journal of the Medical Sciences · doi:10.1097/00000441-196012000-00003 · Cited by 115
Cited by
Relation of Body Fat Distribution to Metabolic Complications of Obesity*
KISSEBAH, A. H., VYDELINGUM, N., MURRAY, R., EVANS, D. J., KALKHOFF, R. K., & ADAMS, P. W. (1982) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-54-2-254 · Cited by 1,909
Avenell, A., Broom, J., Brown, T., Poobalan, A., Aucott, L., Stearns, S., Smith, W., Jung, R., Campbell, M., & Grant, A. (2004) · Health Technology Assessment · doi:10.3310/hta8210 · Cited by 1,041
Obesity in anaesthesia and intensive care
Adams, J. P., & Murphy, P. G. (2000) · British Journal of Anaesthesia · doi:10.1093/bja/85.1.91 · Cited by 649
Cardiovascular Risk Factors. Insights From Framingham Heart Study
O'Donnell, C. J., & Elosua, R. (2008) · Revista Española de Cardiología (English Edition) · doi:10.1016/s1885-5857(08)60118-8 · Cited by 265
Powell, J. J., Tucker, L., Fisher, A. G., & Wilcox, K. (1994) · American Journal of Health Promotion · doi:10.4278/0890-1171-8.6.442 · Cited by 50
Metadata
- Authors
- KANNEL, W. B., LEBAUER, E. J., DAWBER, T. R., & MCNAMARA, P. M.
- Venue
- Circulation
- Published
- 1967-04
- Volume
- 35
- Issue
- 4
- Pages
- 734-744
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W1998524503
- Cited by
- 274
- References
- 20
- FWCI
- 17.83
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Relation of Body Weight to Development of Coronary Heart Disease: The Framingham Study. https://app.cochat.ai/papers/10.1161/01.cir.35.4.734
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- KANNEL, W. B., LEBAUER, E. J., DAWBER, T. R., & MCNAMARA, P. M. (1967). Relation of Body Weight to Development of Coronary Heart Disease: The Framingham Study. Circulation. https://doi.org/10.1161/01.cir.35.4.734
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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