Cited by 132Cardiac electrophysiology and arrhythmiasCardiac pacing and defibrillation studiesCardiac Arrhythmias and Treatments

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Natural history of chronic second-degree atrioventricular nodal block

Strasberg, B, Amat-Y-Leon, F, Dhingra, R C, Palileo, E, Swiryn, S, Bauernfeind, R, Wyndham, C, Rosen, K M·1981·Circulation

DOI 10.1161/01.cir.63.5.1043

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Abstract

This report details our experience with documented chronic second-degree atrioventricular (AV) nodal block (proximal to His [H]) in 56 patients. Forty-six men (82%) and 10 women (18%), ages 18-87 years, were studied. Nineteen of the patients (34%) had no organic heart disease (including seven trained athletes) and 37 (66%) had organic heart disease. ECGs in all patients demonstrated episodes of type I second-degree block; five patients also had periods of 2:1 block. Prospective follow-up patients with no organic heart disease (157-2280 days, mean 1395 +/- 636 days) revealed one patient with clear indication for permanent pacing because of bradyarrhythmic symptoms (permanently placed on day 220 of follow-up). Two patients died nonsuddenly. In patients with organic heart disease (prospective follow-up of 60-2950 days, mean 1347 +/- 825 days), pacemakers were implanted in 10 patients, primarily for treatment of congestive heart failure in eight and syncope in two. Sixteen patients died -- three suddenly, seven with congestive heart failure, two of an acute myocardial infarction and four of causes unrelated to cardiac disease. In summary, chronic second-degree AV nodal block has a relatively benign course in patients without organic heart disease. In patients with organic heart disease, prognosis is poor and related to the severity of underlying heart disease.

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Authors: Strasberg, B., Amat-Y-Leon, F., Dhingra, R. C., Palileo, E., Swiryn, S., Bauernfeind, R., Wyndham, C., & Rosen, K. M.
Affiliations: Bauerfeind (Germany) (DE)
Venue: Circulation
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 1981-05
Volume: 63
Issue: 5
Pages: 1043-1049
ISSN: 0009-7322 (ISSN-L)
1524-4539
DOI: 10.1161/01.cir.63.5.1043
OpenAlex: W1993507703
Cited by: 132
References: 20
Citations by year: 2026: 3 · 2024: 2 · 2023: 1 · 2022: 5 · 2021: 6 · 2020: 2 · 2019: 3 · 2018: 5 · 2017: 2 · 2016: 4 · 2015: 1 · 2014: 6 · 2013: 3 · 2012: 8
FWCI: 4.27
Type: journal article
Language: en
Open access: closed
Locations: Circulation (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac pacing and defibrillation studies
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Arrhythmias and Treatments
Keywords: second-degree atrioventricular block, organic heart disease, pacemaker implantation, congestive heart failure, syncope, sudden cardiac death, prognosis, natural history (disease), athletes
MeSH terms: Adolescent, Adult, Aged, Chronic Disease, Electrocardiography, Electrophysiology, Female, Heart Block, Heart Diseases, Humans, Male, Middle Aged, Pacemaker, Artificial, Syncope, Radiography, Thoracic

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Natural history of chronic second-degree atrioventricular nodal block

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