The DOI matches its Crossref record; 53 of the 53 references it cites were found in a registry or an index.
Sphygmomanometrically Determined Pulse Pressure Is a Powerful Independent Predictor of Recurrent Events After Myocardial Infarction in Patients With Impaired Left Ventricular Function
Abstract
Background There is increasing evidence of a link between conduit vessel stiffness and cardiovascular events, although the association has never been tested in a large post–myocardial infarction patient population. Methods and Results We evaluated the relationship between baseline pulse pressure, measured by sphygmomanometry 3 to 16 days after myocardial infarction, and subsequent adverse clinical events in the 2231 patients enrolled in the SAVE Trial. Increased pulse pressure was associated with increased age, left ventricular ejection fraction, female sex, history of prior infarction, diabetes, and hypertension and use of digoxin and calcium channel blockers. Over a 42-month period, there were 503 deaths, 422 cardiovascular deaths, and 303 myocardial infarctions. Pulse pressure was significantly related to each of these end points as a univariate predictor. In a multivariate analysis, pulse pressure remained a significant predictor of total mortality (relative risk, 1.08 per 10 mm Hg increment in pulse pressure; 95% CI, 1.00 to 1.17; P <.05) and recurrent myocardial infarction (relative risk, 1.12; 95% CI, 1.01 to 1.23; P <.05) after control for age; left ventricular ejection fraction; mean arterial pressure; sex; treatment arm (captopril or placebo); smoking history; history of prior myocardial infarction, diabetes, or hypertension; and treatment with β-blockers, calcium channel blockers, digoxin, aspirin, or thrombolytic therapy. Conclusions These data provide strong evidence for a link between pulse pressure, which is related to conduit vessel stiffness, and subsequent cardiovascular events after myocardial infarction in patients with left ventricular dysfunction.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Pfeffer, M. A., Braunwald, E., Moyé, L. A., Basta, L., Brown, E. J., Cuddy, T. E., Davis, B. R., Geltman, E. M., Goldman, S., Flaker, G. C., et al. (1992) · New England Journal of Medicine · doi:10.1056/nejm199209033271001 · Cited by 5,911
Self-citationLevy, D., Garrison, R. J., Savage, D. D., Kannel, W. B., & Castelli, W. P. (1990) · New England Journal of Medicine · doi:10.1056/nejm199005313222203 · Cited by 5,699
Hemodynamic Patterns of Age-Related Changes in Blood Pressure: The Framingham Heart Study
Franklin, S. S., Gustin, W., Wong, N. D., Larson, M. G., Weber, M. A., Kannel, W. B., & Levy, D. (1997) · Circulation · doi:10.1161/01.cir.96.1.308 · Cited by 2,321
McDonald's Blood Flow in Arteries: Theoretical, Experimental and Clinical Principles
Vlachopoulos, C., O'Rourke, M., & Nichols, W. W. (2011) · doi:10.1201/b13568 · Cited by 1,613
Chen, C.-H., Nevo, E., Fetics, B., Pak, P. H., Yin, F. C. P., Maughan, W. L., & Kass, D. A. (1997) · Circulation · doi:10.1161/01.cir.95.7.1827 · Cited by 1,307
Nifedipine: Dose-Related Increase in Mortality in Patients With Coronary Heart Disease
Furberg, C. D., Psaty, B. M., & Meyer, J. V. (1995) · Circulation · doi:10.1161/01.cir.92.5.1326 · Cited by 1,173
Noninvasive determination of age-related changes in the human arterial pulse.
Kelly, R., Hayward, C., Avolio, A., & O'Rourke, M. (1989) · Circulation · doi:10.1161/01.cir.80.6.1652 · Cited by 1,141
CASALE, P. N., DEVEREUX, R. B., MILNER, M., ZULLO, G., HARSHFIELD, G. A., PICKERING, T. G., & LARAGH, J. H. (1986) · Annals of Internal Medicine · doi:10.7326/0003-4819-105-2-173 · Cited by 1,078
Avolio, A. P., Chen, S. G., Wang, R. P., Zhang, C. L., Li, M. F., & O'Rourke, M. F. (1983) · Circulation · doi:10.1161/01.cir.68.1.50 · Cited by 965
Experimental Subendocardial Ischemia in Dogs with Normal Coronary Arteries
BUCKBERG, G. D., FIXLER, D. E., ARCHIE, J. P., & HOFFMAN, J. I. E. (1972) · Circulation Research · doi:10.1161/01.res.30.1.67 · Cited by 845
Cited by
Laurent, S., Boutouyrie, P., Asmar, R., Gautier, I., Laloux, B., Guize, L., Ducimetiere, P., & Benetos, A. (2001) · Hypertension · doi:10.1161/01.hyp.37.5.1236 · Cited by 3,856
Arterial Stiffness and Cardiovascular Events: The Framingham Heart Study
Mitchell, G. F., Hwang, S.-J., Vasan, R. S., Larson, M. G., Pencina, M. J., Hamburg, N. M., Vita, J. A., Levy, D., & Benjamin, E. J. (2010) · Circulation · doi:10.1161/circulationaha.109.886655 · Cited by 2,225
Self-citationMechanisms, Pathophysiology, and Therapy of Arterial Stiffness
Zieman, S. J., Melenovsky, V., & Kass, D. A. (2005) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/01.atv.0000160548.78317.29 · Cited by 1,854
Is Pulse Pressure Useful in Predicting Risk for Coronary Heart Disease?: The Framingham Heart Study
Franklin, S. S., Khan, S. A., Wong, N. D., Larson, M. G., & Levy, D. (1999) · Circulation · doi:10.1161/01.cir.100.4.354 · Cited by 1,759
Pulse pressure—a review of mechanisms and clinical relevance
Dart, A. M., & Kingwell, B. A. (2001) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(01)01108-1 · Cited by 836
Metadata
- Authors
- Mitchell, G. F., Moyé, L. A., Braunwald, E., Rouleau, J.-L., Bernstein, V., Geltman, E. M., Flaker, G. C., Pfeffer, M. A., & Investigators, F. T. S.
- Venue
- Circulation
- Published
- 1997-12-16
- Volume
- 96
- Issue
- 12
- Pages
- 4254-4260
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W2125097212
- Cited by
- 531
- References
- 53
- FWCI
- 14.18
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Sphygmomanometrically Determined Pulse Pressure Is a Powerful Independent Predictor of Recurrent Events After Myocardial Infarction in Patients With Impaired Left Ventricular Function. https://app.cochat.ai/papers/10.1161/01.cir.96.12.4254
- The paper
- Mitchell, G. F., Moyé, L. A., Braunwald, E., Rouleau, J.-L., Bernstein, V., Geltman, E. M., Flaker, G. C., Pfeffer, M. A., & Investigators, F. T. S. (1997). Sphygmomanometrically Determined Pulse Pressure Is a Powerful Independent Predictor of Recurrent Events After Myocardial Infarction in Patients With Impaired Left Ventricular Function. Circulation. https://doi.org/10.1161/01.cir.96.12.4254
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
