The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.
Antibiotic Prophylaxis for Permanent Pacemaker Implantation: A Meta-Analysis
Open accessAbstract
Background —Infection remains a serious complication after permanent pacemaker implantation. Antibiotic prophylaxis is frequently prescribed at the time of insertion to reduce its incidence, although results of well-designed, controlled studies are lacking. Methods and Results —We performed a meta-analysis of all available randomized trials to evaluate the effectiveness of antibiotic prophylaxis to reduce infection rates after permanent pacemaker implantation. Reports of trials were identified through a Medline, Embase, Current Contents, and an extensive bibliography search. Trials that met the following criteria were included: (1) prospective, randomized, controlled, open or blind trials; (2) patients assigned to a systemic antibiotic group or a control group; (3) end point events related to any infection after pacemaker implantation: wound infection, septicemia, pocket abscess, purulent secretion, right infective endocarditis, inflammatory signs, a positive culture, septic pulmonary embolism, or repeat operation for an infective complication. Seven trials met the inclusion criteria. They included 2023 patients with established permanent pacemaker implantation (new implants or replacements). The incidence of end point events in control groups ranged from 0% to 12%. The meta-analysis suggested a consistent protective effect of antibiotic pretreatment ( P =.0046; common odds ratio: 0.256, 95% confidence interval: 0.10 to 0.656). Conclusions —Results of the present meta-analysis suggest that systemic antibiotic prophylaxis significantly reduces the incidence of potentially serious infective complications after permanent pacemaker implantation. They support the use of prophylactic antibiotics at the time of pacemaker insertion to prevent short-term pocket infection, skin erosion or septicemia.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The combination of estimates from different experiments
Cochran, W. G. (1954) · Biometrics · doi:10.2307/3001666 · Cited by 5,380
The Timing of Prophylactic Administration of Antibiotics and the Risk of Surgical-Wound Infection
Classen, D. C., Evans, R. S., Pestotnik, S. L., Horn, S. D., Menlove, R. L., & Burke, J. P. (1992) · New England Journal of Medicine · doi:10.1056/nejm199201303260501 · Cited by 1,739
A general parametric approach to the meta‐analysis of randomized clinical trials
Whitehead, A., & Whitehead, J. (1991) · Statistics in Medicine · doi:10.1002/sim.4780101105 · Cited by 750
Systemic Infection Related to Endocarditis on Pacemaker Leads: Clinical Presentation and Management
Klug, D., Lacroix, D., Savoye, C., Goullard, L., Grandmougin, D., Hennequin, J. L., Kacet, S., & Lekieffre, J. (1997) · Circulation · doi:10.1161/01.cir.95.8.2098 · Cited by 593
Pacemaker Endocarditis Report of 44 Cases and Review of the Literature
Arber, N., Pras, E., Copperman, Y., Schapiro, J. M., Meiner, V., Lossos, I. S., Militianu, A., Hassin, D., Pras, E., Shai, A., et al. (1994) · Medicine · doi:10.1097/00005792-199411000-00003 · Cited by 251
Permanent pacemaker infections: Characterization and management
Choo, M. H., Holmes, D. R., Gersh, B. J., Maloney, J. D., Merideth, J., Pluth, J. R., & Trusty, J. (1981) · The American Journal of Cardiology · doi:10.1016/0002-9149(81)90088-6 · Cited by 177
Nonvalvular Infections of the Cardiovascular System
Kearney, R. A., Eisen, H. J., & Wolf, J. E. (1994) · Annals of Internal Medicine · doi:10.7326/0003-4819-121-3-199408010-00010 · Cited by 142
Hill, P. E. (1987) · Pacing and Clinical Electrophysiology · doi:10.1111/j.1540-8159.1987.tb04521.x · Cited by 137
Considerations for the meta-analysis of randomized clinical trials
Boissel, J., Blanchard, J., Panak, E., Peyrieux, J., & Sacks, H. S. (1989) · Controlled Clinical Trials · doi:10.1016/0197-2456(89)90067-6 · Cited by 119
Barold, S. S. (1985) · Futura Pub. Co. eBooks · Cited by 67
Cited by
Guideline for Prevention of Surgical Site Infection, 1999
Mangram, A. J., Horan, T. C., Pearson, M. L., Silver, L. C., Jarvis, W. R., & The Hospital Infection Control Practices Advisory Committee (1999) · Infection Control & Hospital Epidemiology · doi:10.1086/501620 · Cited by 4,595
Clinical practice guidelines for antimicrobial prophylaxis in surgery
Bratzler, D. W., Dellinger, E. P., Olsen, K. M., Perl, T. M., Auwaerter, P. G., Bolon, M. K., Fish, D. N., Napolitano, L. M., Sawyer, R. G., Slain, D., et al. (2013) · American Journal of Health-System Pharmacy · doi:10.2146/ajhp120568 · Cited by 2,591
Guidelines on the prevention, diagnosis, and treatment of infective endocarditis (new version 2009)
Endorsed by the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) and by the International Society of Chemotherapy (ISC) for Infection and Cancer, Habib, G., Hoen, B., Tornos, P., Thuny, F., Prendergast, B., Vilacosta, I., Moreillon, P., de Jesus Antunes, M., Thilen, U., et al. (2009) · European Heart Journal · doi:10.1093/eurheartj/ehp285 · Cited by 2,014
Self-citation2021 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy
Glikson, M., Nielsen, J. C., Kronborg, M. B., Michowitz, Y., Auricchio, A., Barbash, I. M., Barrabés, J. A., Boriani, G., Braunschweig, F., Brignole, M., et al. (2021) · European Heart Journal · doi:10.1093/eurheartj/ehab364 · Cited by 2,019
Egger, M., Jüni, P., Bartlett, C., Holenstein, F., & Sterne, J. (2003) · Health Technology Assessment · doi:10.3310/hta7010 · Cited by 1,181
Metadata
- Authors
- Da Costa, A., Kirkorian, G., Cucherat, M., Delahaye, F., Chevalier, P., Cerisier, A., Isaaz, K., & Touboul, P.
- Venue
- Circulation
- Published
- 1998-05-12
- Volume
- 97
- Issue
- 18
- Pages
- 1796-1801
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W1987671633
- Cited by
- 362
- References
- 14
- FWCI
- 7.29
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Antibiotic Prophylaxis for Permanent Pacemaker Implantation: A Meta-Analysis. https://app.cochat.ai/papers/10.1161/01.cir.97.18.1796
- The paper
- Da Costa, A., Kirkorian, G., Cucherat, M., Delahaye, F., Chevalier, P., Cerisier, A., Isaaz, K., & Touboul, P. (1998). Antibiotic Prophylaxis for Permanent Pacemaker Implantation: A Meta-Analysis. Circulation. https://doi.org/10.1161/01.cir.97.18.1796
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
