The DOI matches its Crossref record; 35 of the 35 references it cites were found in a registry or an index.
Hyperuricemia and Incidence of Hypertension Among Men Without Metabolic Syndrome
Abstract
The aim of this project was to study the risk of developing hypertension over a 6-year follow-up in normotensive men with baseline hyperuricemia (serum uric acid >7.0 mg/dL) but without diabetes/glucose intolerance or metabolic syndrome. We analyzed the data on men without metabolic syndrome or hypertension at baseline from the Multiple Risk Factor Intervention Trial. These men (n=3073; age: 35 to 57 years) were followed for an average of 6 years by annual examinations. Follow-up blood pressure among those with baseline was consistently higher than among those with normal serum uric acid concentration. We used Cox regression models for adjustment for the effects of serum creatinine, body mass index, age, blood pressure, proteinuria, serum cholesterol and triglycerides, alcohol and tobacco use, risk factor interventions, and use of diuretics. In these models, normotensive men with baseline hyperuricemia had an 80% excess risk for incident hypertension (hazard ratio: 1.81; 95% CI: 1.59 to 2.07) compared with those who did not. Each unit increase in serum uric acid was associated with a 9% increase in the risk for incident hypertension (hazard ratio: 1.09; 95% CI: 1.02 to 1.17). We conclude that the hyperuricemia–hypertension risk relationship is present among normotensive middle-aged men without diabetes/glucose intolerance or metabolic syndrome.
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Chobanian, A. V., Bakris, G. L., Black, H. R., Cushman, W. C., Green, L. A., Izzo, J. L., Jones, D. W., Materson, B. J., Oparil, S., Wright, J. T., et al. (2003) · Hypertension · doi:10.1161/01.hyp.0000107251.49515.c2 · Cited by 13,271
The environment and disease: association or causation?
Hill, A. B. (2015) · Journal of the Royal Society of Medicine · doi:10.1177/0141076814562718 · Cited by 7,285
The Environment and Disease: Association or Causation?
Hill, A. B. (1965) · Proceedings of the Royal Society of Medicine · doi:10.1177/003591576505800503 · Cited by 6,974
Burt, V. L., Whelton, P., Roccella, E. J., Brown, C., Cutler, J. A., Higgins, M., Horan, M. J., & Labarthe, D. (1995) · Hypertension · doi:10.1161/01.hyp.25.3.305 · Cited by 2,998
A Note on Robust Variance Estimation for Cluster‐Correlated Data
Williams, R. L. (2000) · Biometrics · doi:10.1111/j.0006-341x.2000.00645.x · Cited by 2,501
Febuxostat Compared with Allopurinol in Patients with Hyperuricemia and Gout
Becker, M. A., Schumacher, H. R., Wortmann, R. L., MacDonald, P. A., Eustace, D., Palo, W. A., Streit, J., & Joseph-Ridge, N. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa050373 · Cited by 1,357
Self-citation- Statistical Models for Epidemiology
(2013) · Bayesian Methods in Epidemiology · doi:10.1201/b15382-9 · Cited by 1,346
Diagnosis and Classification of Diabetes Mellitus
American Diabetes Association (2006) · Diabetes Care · doi:10.2337/diacare.29.s1.06.s43 · Cited by 924
Mazzali, M., Kanellis, J., Han, L., Feng, L., Xia, Y.-Y., Chen, Q., Kang, D.-H., Gordon, K. L., Watanabe, S., Nakagawa, T., et al. (2002) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00283.2001 · Cited by 826
Masuo, K., Kawaguchi, H., Mikami, H., Ogihara, T., & Tuck, M. L. (2003) · Hypertension · doi:10.1161/01.hyp.0000091371.53502.d3 · Cited by 516
Cited by
Mancia, G., Kreutz, R., Brunström, M., Burnier, M., Grassi, G., Januszewicz, A., Muiesan, M. L., Tsioufis, K., Agabiti-Rosei, E., Algharably, E. A. E., et al. (2023) · Journal of Hypertension · doi:10.1097/hjh.0000000000003480 · Cited by 3,473
Johnson, R. J., Segal, M. S., Sautin, Y., Nakagawa, T., Feig, D. I., Kang, D.-H., Gersch, M. S., Benner, S., & Sánchez-Lozada, L. G. (2007) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/86.4.899 · Cited by 1,075
Richette, P., & Bardin, T. (2010) · The Lancet · doi:10.1016/s0140-6736(09)60883-7 · Cited by 915
Feig, D. I., Soletsky, B., & Johnson, R. J. (2008) · JAMA · doi:10.1001/jama.300.8.924 · Cited by 914
Uric Acid and Incident Kidney Disease in the Community
Weiner, D. E., Tighiouart, H., Elsayed, E. F., Griffith, J. L., Salem, D. N., & Levey, A. S. (2008) · Journal of the American Society of Nephrology · doi:10.1681/asn.2007101075 · Cited by 462
Metadata
- Authors
- Krishnan, E., Kwoh, C. K., Schumacher, H. R., & Kuller, L.
- Venue
- Hypertension
- Published
- 2007-02
- Volume
- 49
- Issue
- 2
- Pages
- 298-303
- ISSN
- 0194-911X (ISSN-L)
- 1524-4563
- OpenAlex
- W2126654035
- Cited by
- 293
- References
- 35
- FWCI
- 8.19
- Type
- journal article
- Language
- en
- Open access
- closed
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- Krishnan, E., Kwoh, C. K., Schumacher, H. R., & Kuller, L. (2007). Hyperuricemia and Incidence of Hypertension Among Men Without Metabolic Syndrome. Hypertension. https://doi.org/10.1161/01.hyp.0000254480.64564.b6
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