The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Elements of a Paracrine Tubular Renin-Angiotensin System Along the Entire Nephron
Abstract
Abstract —The renin-angiotensin system is a major regulator of body sodium, predominantly through the actions of intrarenal angiotensin II of unclear origin. We show that polarized epithelium of the proximal tubule synthesizes and secretes angiotensinogen at its apical side and that the protein can be detected in urine as a function of dietary sodium. Furthermore, we demonstrate that renin is expressed and secreted in a restricted nephron segment, the connecting tubule, also in a sodium-dependent fashion. A paracrine renin-angiotensin system operating along the entire nephron may contribute to long-term arterial pressure regulation by integrating distant tubular sodium-reabsorbing functions.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Larson, D. M., Wrobleski, M. J., Sagar, G. D., Westphale, E. M., & Beyer, E. C. (1997) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1997.272.2.c405 · Cited by 126
Cited by
Regulation of Intrarenal Angiotensin II in Hypertension
Navar, L. G., Harrison-Bernard, L. M., Nishiyama, A., & Kobori, H. (2002) · Hypertension · doi:10.1161/hy0202.103821 · Cited by 375
The renin-angiotensin-aldosterone system, glucose metabolism and diabetes
Giacchetti, G., Sechi, L. A., Rilli, S., & Carey, R. M. (2005) · Trends in Endocrinology & Metabolism · doi:10.1016/j.tem.2005.02.003 · Cited by 267
Ariza, A. C., Deen, P. M. T., & Robben, J. H. (2012) · Frontiers in Endocrinology · doi:10.3389/fendo.2012.00022 · Cited by 211
Lavoie, J. L., Lake-Bruse, K. D., & Sigmund, C. D. (2004) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00402.2003 · Cited by 94
Expression of Renin-Angiotensin System Components in the Taste Organ of Mice
Shigemura, N., Takai, S., Hirose, F., Yoshida, R., Sanematsu, K., & Ninomiya, Y. (2019) · Nutrients · doi:10.3390/nu11092251 · Cited by 65
Metadata
- Authors
- Rohrwasser, A., Morgan, T., Dillon, H. F., Zhao, L., Callaway, C. W., Hillas, E., Zhang, S., Cheng, T., Inagami, T., Ward, K., Terreros, D. A., & Lalouel, J.-M.
- Venue
- Hypertension
- Published
- 1999-12
- Volume
- 34
- Issue
- 6
- Pages
- 1265-1274
- ISSN
- 0194-911X (ISSN-L)
- 1524-4563
- OpenAlex
- W2164145533
- Cited by
- 292
- References
- 1
- FWCI
- 4.53
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Elements of a Paracrine Tubular Renin-Angiotensin System Along the Entire Nephron. https://app.cochat.ai/papers/10.1161/01.hyp.34.6.1265
- The paper
- Rohrwasser, A., Morgan, T., Dillon, H. F., Zhao, L., Callaway, C. W., Hillas, E., Zhang, S., Cheng, T., Inagami, T., Ward, K., Terreros, D. A., & Lalouel, J.-M. (1999). Elements of a Paracrine Tubular Renin-Angiotensin System Along the Entire Nephron. Hypertension. https://doi.org/10.1161/01.hyp.34.6.1265
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
