The DOI matches its Crossref record; 126 of the 126 references it cites were found in a registry or an index.
Trafficking of G Protein–Coupled Receptors
Open accessAbstract
G protein–coupled receptors (GPCRs) play an integral role in the signal transduction of an enormous array of biological phenomena, thereby serving to modulate at a molecular level almost all components of human biology. This role is nowhere more evident than in cardiovascular biology, where GPCRs regulate such core measures of cardiovascular function as heart rate, contractility, and vascular tone. GPCR/ligand interaction initiates signal transduction cascades, and requires the presence of the receptor at the plasma membrane. Plasma membrane localization is in turn a function of the delivery of a receptor to and removal from the cell surface, a concept defined most broadly as receptor trafficking. This review illuminates our current view of GPCR trafficking, particularly within the cardiovascular system, as well as highlights the recent and provocative finding that components of the GPCR trafficking machinery can facilitate GPCR signaling independent of G protein activation.
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Role of CRF Receptor Signaling in Stress Vulnerability, Anxiety, and Depression
Hauger, R. L., Risbrough, V., Oakley, R. H., Olivares‐Reyes, J. A., & Dautzenberg, F. M. (2009) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2009.05011.x · Cited by 217
The physiological and pathophysiological functions of renal and extrarenal vasopressin V2 receptors
Juul, K. V., Bichet, D. G., Nielsen, S., & Nørgaard, J. P. (2014) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00604.2013 · Cited by 156
Conti, F., Sertic, S., Reversi, A., & Chini, B. (2009) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.90590.2008 · Cited by 113
Villar, V. A. M., Armando, I., Sanada, H., Frazer, L. C., Russo, C. M., Notario, P. M., Lee, H., Comisky, L., Russell, H. A., Yang, Y., et al. (2013) · The FASEB Journal · doi:10.1096/fj.12-208439 · Cited by 42
Aruna, K., Pal, S., Khanna, A., & Bhattacharyya, S. (2024) · The Journal of Membrane Biology · doi:10.1007/s00232-024-00326-z · Cited by 6
Metadata
- Authors
- Drake, M. T., Shenoy, S. K., & Lefkowitz, R. J.
- Venue
- Circulation Research
- Published
- 2006-09-15
- Volume
- 99
- Issue
- 6
- Pages
- 570-582
- ISSN
- 0009-7330 (ISSN-L)
- 1524-4571
- OpenAlex
- W2120401458
- Cited by
- 320
- References
- 126
- FWCI
- 6.38
- Type
- journal article
- Language
- en
- Open access
- bronze
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