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Cited by 786

The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.

Equations for Measuring Blood Flow by External Monitoring of Radioisotopes

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ZIERLER, KENNETH L.·1965·Circulation Research

Abstract

It is possible by external monitoring alone to measure blood flow per unit volume through any vascular bed accessible to external monitoring of the radioactive tracer if the tracer input function or if the quantity of tracer entering the system is known. The methods proposed exploit the fact that the mean transit time through the system is the flow per unit volume of distribution of tracer. The equations are free of assumptions that require solutions as exponentials or any other specified frequency function of transit times. If the input function is known, measurement of the concentration of tracer in blood leaving the part sensed by the external detector, combined with external detection of radioactivity, can lead to measurement of absolute blood flow.

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Metadata

Authors
ZIERLER, K. L.
Venue
Circulation Research
Published
1965-04
Volume
16
Issue
4
Pages
309-321
ISSN
  • 0009-7330 (ISSN-L)
  • 1524-4571
OpenAlex
W2071233005
Cited by
786
References
5
FWCI
35.06
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Equations for Measuring Blood Flow by External Monitoring of Radioisotopes. https://app.cochat.ai/papers/10.1161/01.res.16.4.309
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ZIERLER, K. L. (1965). Equations for Measuring Blood Flow by External Monitoring of Radioisotopes. Circulation Research. https://doi.org/10.1161/01.res.16.4.309

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.