The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Regional Cerebral low in Man Determined by Intral-artrial Injection of Radioactive Inert Gas
Abstract
The intra-arterial injection of a radioactive inert gas is described for measurement of regional cerebral blood flow in man from externally recorded clearance curves. The stochastic analysis for calculating the average cerebral blood flow in ml/100 g/min is compared to an analysis of the curve into two compartments with fast and slow clearance rates representing flow in grey and white cerebral matter respectively. An estimate of the relative weight of the grey matter in the cerebral region counted from brain is also obtained. A detailed description is given of the experimental procedure using krypton 85 or xenon 133 as the tracer gas. A brief injection time and short time constant in the recording ratemeter are important for obtaining a correct estimate of the maximal height of the curve. Mono-exponential extrapolation beyond the time of observation (usually 15 minutes) is employed. The practical procedure for calculating the results according to the stochastic and compartmental models are described with particular emphasis on the simple "10 minutes-average-flow-value, " CBF (10) which corresponds directly to the results of the classical Kety-Schmidt inert gas inhalation method for measurement of the average blood flow of the whole brain.
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Citations
Cites
Catheter Replacement of the Needle in Percutaneous Arteriography: A new technique
Seldinger, S. I. (1953) · Acta Radiologica · doi:10.3109/00016925309136722 · Cited by 3,270
Kety, S. S., & Schmidt, C. F. (1948) · Journal of Clinical Investigation · doi:10.1172/jci101994 · Cited by 2,059
THE THEORY AND APPLICATIONS OF THE EXCHANGE OF INERT GAS AT THE LUNGS AND TISSUES
KETY, S. S. (1951) · Pharmacological Reviews · doi:10.1016/s0031-6997(25)07246-1 · Cited by 1,663
On the Theory of the Indicator-Dilution Method for Measurement of Blood Flow and Volume
Meier, P., & Zierler, K. L. (1954) · Journal of Applied Physiology · doi:10.1152/jappl.1954.6.12.731 · Cited by 1,274
Regional Blood Flow of the Cerebral Cortex Determined by Krypton85
INGVAR, B. D. H., & LASSEN, N. A. (1962) · Acta Physiologica Scandinavica · doi:10.1111/j.1748-1716.1962.tb02356.x · Cited by 300
Self-citationRegional cerebral blood flow in man determined by krypton 85
Lassen, N. A., Høledt-Hasmussen, K., Søremen, S. C., Skinhøj, E., Cronquist, S., Bodforss, B., Eng, E., & Ingvar, D. H. (1963) · Neurology · doi:10.1212/wnl.13.9.719 · Cited by 290
Self-citationThe Cerebral Blood Flow in Man Determined by the Use of Radioactive Krypton
LASSEN, N. A., & MUNCK, O. (1955) · Acta Physiologica Scandinavica · doi:10.1111/j.1748-1716.1955.tb01191.x · Cited by 264
Self-citationInhaltsberechnungen der Rinden- und Marksubstanz des Grosshirns durch planimetrische Messungen
Jaeger, R. (1914) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/bf02028457 · Cited by 22
Cited by
Responses of cerebral arteries and arterioles to acute hypotension and hypertension
Kontos, H. A., Wei, E. P., Navari, R. M., Levasseur, J. E., Rosenblum, W. I., & Patterson, J. L. (1978) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1978.234.4.h371 · Cited by 699
Regional Blood Flow in the Cerebral Cortex, Measured Simultaneously by Heat and Inert Gas Clearance
Betz, E., Ingvar, D. H., Lassen, N. A., & Schmahl, F. W. (1966) · Acta Physiologica Scandinavica · doi:10.1111/j.1748-1716.1966.tb03280.x · Cited by 320
Self-citationPASZTOR, E., SYMON, L., DORSCH, N. W. C., & BRANSTON, N. M. (1973) · Stroke · doi:10.1161/01.str.4.4.556 · Cited by 320
Regional Cerebral Blood Flow in Acute Apoplexy: The "Luxury Perfusion Syndrome" of Brain Tissue
Høedt-Rasmussen, K. (1967) · Archives of Neurology · doi:10.1001/archneur.1967.00470270049007 · Cited by 271
Self-citationMadsen, P. L., Hasselbalch, S. G., Hagemann, L. P., Olsen, K. S., Bülow, J., Holm, S., Wildschiødtz, G., Paulson, O. B., & Lassen, N. A. (1995) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.1995.60 · Cited by 264
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Metadata
- Authors
- Høedt-Rasmussen, K., Sveinsdottir, E., & Lassen, N. A.
- Venue
- Circulation Research
- Published
- 1966-03
- Volume
- 18
- Issue
- 3
- Pages
- 237-247
- ISSN
- 0009-7330 (ISSN-L)
- 1524-4571
- OpenAlex
- W2159462894
- Cited by
- 422
- References
- 8
- FWCI
- 40.30
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Regional Cerebral low in Man Determined by Intral-artrial Injection of Radioactive Inert Gas. https://app.cochat.ai/papers/10.1161/01.res.18.3.237
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- Høedt-Rasmussen, K., Sveinsdottir, E., & Lassen, N. A. (1966). Regional Cerebral low in Man Determined by Intral-artrial Injection of Radioactive Inert Gas. Circulation Research. https://doi.org/10.1161/01.res.18.3.237
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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