The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Stress (Heat Shock) Proteins: Molecular Chaperones in Cardiovascular Biology and Disease
Open accessAbstract
Abstract —How a cell responds to stress is a central problem in cardiovascular biology. Diverse physiological stresses (eg, heat, hemodynamics, mutant proteins, and oxidative injury) produce multiple changes in a cell that ultimately affect protein structures and function. Cells from different phyla initiate a cascade of events that engage essential proteins, the molecular chaperones, in decisions to repair or degrade damaged proteins as a defense strategy to ensure survival. Accumulative evidence indicates that molecular chaperones such as the heat shock family of stress proteins (HSPs) actively participate in an array of cellular processes, including cytoprotection. The versatility of the ubiquitous HSP family is further enhanced by stress-inducible regulatory networks, both at the transcriptional and posttranscriptional levels. In the present review, we discuss the regulation and function of HSP chaperones and their clinical significance in conditions such as cardiac hypertrophy, vascular wall injury, cardiac surgery, ischemic preconditioning, aging, and, conceivably, mutations in genes encoding contractile proteins and ion channels.
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Cites
Biochemistry of nitric oxide and its redox-activated forms
Stamler, J. S., Singel, D. J., & Loscalzo, J. (1992) · Science · doi:10.1126/science.1281928 · Cited by 2,744
Geisterfer-Lowrance, A. A. T., Kass, S., Tanigawa, G., Vosberg, H.-P., McKenna, W., Seidman, C. E., & Seidman, J. G. (1990) · Cell · doi:10.1016/0092-8674(90)90274-i · Cited by 1,380
Heat Shock Transcription Factors: Structure and Regulation
Wu, C. (1995) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cb.11.110195.002301 · Cited by 1,231
Sorger, P. K., & Pelham, H. R. B. (1988) · Cell · doi:10.1016/s0092-8674(88)91219-6 · Cited by 832
Lee, P. J., Jiang, B.-H., Chin, B. Y., Iyer, N. V., Alam, J., Semenza, G. L., & Choi, A. K. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.9.5375 · Cited by 782
Borkovich, K. A., Farrelly, F. W., Finkelstein, D. B., Taulien, J., & Lindquist, S. (1989) · Molecular and Cellular Biology · doi:10.1128/mcb.9.9.3919 · Cited by 641
Risk factors that attenuate the female coronary disease advantage
Kannel, W. B. (1995) · Archives of Internal Medicine · doi:10.1001/archinte.1995.00430010063008 · Cited by 381
Cited by
Kregel, K. C. (2002) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01267.2001 · Cited by 1,455
Ischemia–Reperfusion–induced Lung Injury
de Perrot, M., Liu, M., Waddell, T. K., & Keshavjee, S. (2003) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200207-670so · Cited by 962
Cardiomyocyte Grafting for Cardiac Repair: Graft Cell Death and Anti-Death Strategies
Zhang, M., Methot, D., Poppa, V., Fujio, Y., Walsh, K., & Murry, C. E. (2001) · Journal of Molecular and Cellular Cardiology · doi:10.1006/jmcc.2001.1367 · Cited by 878
Formation of Human Myocardium in the Rat Heart from Human Embryonic Stem Cells
Laflamme, M. A., Gold, J., Xu, C., Hassanipour, M., Rosler, E., Police, S., Muskheli, V., & Murry, C. E. (2005) · The American Journal of Pathology · doi:10.1016/s0002-9440(10)62041-x · Cited by 448
Yet, S.-F., Tian, R., Layne, M. D., Wang, Z. Y., Maemura, K., Solovyeva, M., Ith, B., Melo, L. G., Zhang, L., Ingwall, J. S., et al. (2001) · Circulation Research · doi:10.1161/hh1401.093314 · Cited by 420
Metadata
- Authors
- Benjamin, I. J., & McMillan, D. R.
- Venue
- Circulation Research
- Published
- 1998-07-27
- Volume
- 83
- Issue
- 2
- Pages
- 117-132
- ISSN
- 0009-7330 (ISSN-L)
- 1524-4571
- OpenAlex
- W2140735579
- Cited by
- 842
- References
- 7
- FWCI
- 12.16
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Benjamin, I. J., & McMillan, D. R. (1998). Stress (Heat Shock) Proteins: Molecular Chaperones in Cardiovascular Biology and Disease. Circulation Research. https://doi.org/10.1161/01.res.83.2.117
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
