The DOI matches its Crossref record.
Altered Patterns of Gene Expression in Response to Myocardial Infarction
Abstract
Abstract —The use of cDNA microarrays has made it possible to simultaneously analyze gene expression for thousands of genes. Microarray technology was used to evaluate the expression of >4000 genes in a rat model of myocardial infarction. More than 200 genes were identified that showed differential expression in response to myocardial infarction. Gene expression changes were monitored from 2 to 16 weeks after infarction in 2 regions of the heart, the left ventricle free wall and interventricular septum. A novel clustering program was used to identify patterns of expression within this large set of data. Unique patterns were revealed within the transcriptional responses that illuminate changes in biological processes associated with myocardial infarction.
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Citations
Cited by
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Travers, J. G., Kamal, F. A., Robbins, J., Yutzey, K. E., & Blaxall, B. C. (2016) · Circulation Research · doi:10.1161/circresaha.115.306565 · Cited by 1,596
Biomarkers of Cardiovascular Disease: Molecular Basis and Practical Considerations
Vasan, R. S. (2006) · Circulation · doi:10.1161/circulationaha.104.482570 · Cited by 1,212
Periostin induces proliferation of differentiated cardiomyocytes and promotes cardiac repair
Kühn, B., del Monte, F., Hajjar, R. J., Chang, Y.-S., Lebeche, D., Arab, S., & Keating, M. T. (2007) · Nature Medicine · doi:10.1038/nm1619 · Cited by 659
Rios, H., Koushik, S. V., Wang, H., Wang, J., Zhou, H.-M., Lindsley, A., Rogers, R., Chen, Z., Maeda, M., Kruzynska-Frejtag, A., et al. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.24.11131-11144.2005 · Cited by 373
Ramsey, S. A., Klemm, S. L., Zak, D. E., Kennedy, K. A., Thorsson, V., Li, B., Gilchrist, M., Gold, E. S., Johnson, C. D., Litvak, V., et al. (2008) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1000021 · Cited by 147
Metadata
- Authors
- Stanton, L. W., Garrard, L. J., Damm, D., Garrick, B. L., Lam, A., Kapoun, A. M., Zheng, Q., Protter, A. A., Schreiner, G. F., & White, R. T.
- Venue
- Circulation Research
- Published
- 2000-05-12
- Volume
- 86
- Issue
- 9
- Pages
- 939-945
- ISSN
- 0009-7330 (ISSN-L)
- 1524-4571
- OpenAlex
- W2151148996
- Cited by
- 367
- References
- 0
- FWCI
- 23.97
- Type
- journal article
- Language
- en
- Open access
- closed
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- Stanton, L. W., Garrard, L. J., Damm, D., Garrick, B. L., Lam, A., Kapoun, A. M., Zheng, Q., Protter, A. A., Schreiner, G. F., & White, R. T. (2000). Altered Patterns of Gene Expression in Response to Myocardial Infarction. Circulation Research. https://doi.org/10.1161/01.res.86.9.939
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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